Results 81 to 90 of about 5,211 (236)
Molecular aspects and comparative genomics of bacteriophage endolysins [PDF]
, 2013 Phages are recognized as the most abundant and diverse entities on the planet. Their diversity is predominantly determined by their dynamic adaptation capacities, when confronted with different selective pressures in an endless cycle of co-evolution with
Azeredo, Joana +7 more
core +1 more source
Untersuchungen zum Ursprung der Substratspezifität von Enzymen der Amidohydrolase‐Superfamilie
Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.Umfassende Analysen zweier Enzymklassen aus der Amidohydrolase‐Superfamilie (AHS) ergaben, dass die Katalyse über eine 1,4‐ bzw. 1,6‐nukleophile konjugierte Addition abläuft und diese Eigenschaft die Substratspezifität bestimmt. Obwohl alle Substrate und Produkte vollständig achiral sind, führt dieser mechanistische Unterschied zu einer invertierten ...
Lukas Drexler +3 more
wiley +1 more source
Chemical approaches to sphingolipid research [PDF]
, 2015 Podeu consultar el llibre complet a: http://hdl.handle.net/2445 ...
Abad Saiz, José Luis +3 more
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Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy [PDF]
, 2010 Heritable changes in gene expression that are not based upon alterations in the DNA sequence are defined as epigenetics. The most common mechanisms of epigenetic regulation are the methylation of CpG islands within the DNA and the modification of amino ...
Björn Hackanson +3 more
core +2 more sources
, 2005 Canavan disease (CD) is an autosomal recessive disorder, characterized by spongiform degeneration of the white matter of the brain. Aspartoacylase (ASPA) hydrolyses N-acetylaspartic acid to aspartate and acetate.
Surendran, Sankar
core
Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds
ChemMedChem, Volume 21, Issue 2, January 2026.Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley +1 more source
Multilayered Organization of Jasmonate Signalling in the Regulation of Root Growth. [PDF]
, 2015 Physical damage can strongly affect plant growth, reducing the biomass of developing organs situated at a distance from wounds. These effects, previously studied in leaves, require the activation of jasmonate (JA) signalling.
Acosta, I.F. +8 more
core +4 more sources
Probing the pan-genome of Listeria monocytogenes: new insights into intraspecific niche expansion and genomic diversification [PDF]
, 2010 Bacterial pathogens often show significant intraspecific variations in ecological fitness, host preference and pathogenic potential to cause infectious disease. The species of Listeria monocytogenes, a facultative intracellular pathogen and the causative
Adam M Phillippy +4 more
core +2 more sources
Salmonella typhimurium's transthyretin-like protein is a host-specific factor important in fecal survival in chickens. [PDF]
, 2012 The transthyretin-like protein (TLP) from Salmonella enterica subspecies I is a periplasmic protein with high level structural similarity to a protein found in mammals and fish.
Hennebry, Sarah C +8 more
core +4 more sources
mBioConjugative type 4 secretion systems (T4SSs) are the main driver for the spread of antibiotic resistance genes and virulence factors in bacteria.
Wei-Sheng Sun +4 more
doaj +1 more source