Results 31 to 40 of about 737,653 (267)

Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2018
Four human (h) carbonic anhydrase isoforms (CA, EC 4.2.1.1), hCA I, II, IV, and VII, were investigated for their activation profile with piperazines belonging to various classes, such as N-aryl-, N-alkyl-, N-acyl-piperazines as well as 2,4-disubstituted ...
Andrea Angeli   +4 more
doaj   +1 more source

Synthesis of Both Ionic Species of Ammonium Dithiocarbamate Derived Cholic Acid Moieties

open access: yesMolecules, 2011
The reaction of 3-aminopropylamide of cholic acid with CS2 produced a bile acid derivative of dithiocarbamic acid which further formed an ammonium salt with another molecule of 3-aminopropylamide of cholic acid.
Erkki Kolehmainen, Juha Koivukorpi
doaj   +1 more source

Boundary of the Range of Transient Random Walk [PDF]

open access: yes, 2016
We study the boundary of the range of simple random walk on $\mathbb{Z}^d$ in the transient regime $d\ge 3$. We show that volumes of the range and its boundary differ mainly by a martingale. As a consequence, we obtain a bound on the variance of order $n\
Asselah, Amine, Schapira, Bruno
core   +2 more sources

Solidity of type III Bernoulli crossed products

open access: yes, 2016
We generalize a theorem of Chifan and Ioana by proving that for any, possibly type III, amenable von Neumann algebra $A_0$, any faithful normal state $\varphi_0$ and any discrete group $\Gamma$, the associated Bernoulli crossed product von Neumann ...
Marrakchi, Amine
core   +2 more sources

Cyclic Comonomers for the Synthesis of Carboxylic Acid and Amine Functionalized Poly(l-Lactic Acid)

open access: yesMolecules, 2015
Degradable aliphatic polyesters such as poly(lactic acid) are widely used in biomedical applications, however, they lack functional moieties along the polymer backbone that are amenable for functionalization reactions or could be the basis for ...
Markus Heiny, V. Prasad Shastri
doaj   +1 more source

Some Incipient Techniques For Improving Efficiency in Computational Mechanics [PDF]

open access: yes, 2008
This contribution presents a review of different techniques available for alleviating simulation cost in computational mechanics. The first one is based on a separated representation of the unknown fields; the second one uses a model reduction based on ...
AMMAR, Amine, CHINESTA, Francisco
core   +9 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Effect of catalase on the growth performance, antioxidation, and microbial metabolism of weaned rabbits

open access: yesCzech Journal of Animal Science, 2023
The present study aimed to investigate the effect of catalase (CAT) on the growth performance, antioxidation, and microbial metabolism of weaned rabbits. Dietary treatments consisted of control and CAT supplementation at 100 (T1), 150 (T2), and 200 IU/kg
Ning Liu   +3 more
doaj   +1 more source

Solid amine compounds as sorbents for carbon dioxide: A concept [PDF]

open access: yes, 1972
Solid amine compounds were examined as possible absorbents for removal of carbon dioxide in life support systems of type which may be employed in high altitude aircraft, spacecraft, or submarines.
Heimlich, P. F.   +2 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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