Results 41 to 50 of about 447,214 (305)
An investigation of nucleophilic substitution reactions of 2,3-dichloro-1,4-naphthoquinone with various nucleophilic reagents [PDF]
Journal of the Serbian Chemical Society, 2015 Novel N- , N,S- and N,O- substituted naphthoquinone compounds were prepared by the reactions of 2,3-dichloro-1,4-naphthoquinone (1) and the corresponding nucleophiles in the presence of chloroform and triethylamine or ethanol solution of Na2CO3.
Ibis Cemil +3 more
doaj +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
, 2020 The mild and efficient hydroxytrifluoromethylation of alkenes with bromotrifluoromethane (CF3Br) and atmospheric oxygen mediated by cobalt-tertiary amine is described.
Wu Fan +15 more
core +1 more source
Uncovering the active species in amine-mediated CO2 reduction to CO on Ag [PDF]
, 2023 Electrochemical reactive capture of CO2, which integrates CO2 capture with its conversion directly from amine and other capture solutions, is of growing interest but introduces considerable complexity to the electrochemical process due to the wide range ...
Mohamed Kheireddine, Aroua +13 more
core +2 more sources
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Near-infrared clusteroluminescence in amine-capped polyesters [PDF]
, 2023 Near-infrared (NIR) luminophores has many advantages in practical applications, however, the fabrication of NIR clusteroluminogens (CLgens) from nonconjugated luminescent polymers is still a big challenge owing to uncontrollable structures and ...
Liu, Bin +10 more
core +2 more sources
, 2016 Amine-Promoted Disproportionation and Redistribution of Trichlorosilane: Formation of Tetradecachlorocyclohexasilane ...
Beon-Kyu Kim (2979168) +3 more
core +2 more sources
Detecting Electron Transport of Amino Acids by Using Conductance Measurement
Sensors, 2017 The single molecular conductance of amino acids was measured by a scanning tunneling microscope (STM) break junction. Conductance measurement of alanine gives out two conductance values at 10−1.85 G0 (1095 nS) and 10−3.7 G0 (15.5 nS), while similar ...
Wei-Qiong Li +8 more
doaj +1 more source