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Expression of Amine Oxidase Proteins in Adrenal Cortical Neoplasm and Pheochromocytoma [PDF]

open access: yesBiomedicines, 2023
We delved into the expression of amine oxidase family proteins and their potential significance in adrenal gland neoplasm. Tissue microarrays were prepared for 132 cases of adrenal cortical neoplasm (ACN) consisting of 115 cases of adrenal cortical ...
Eun Kyung Kim, Ja Seung Koo
doaj   +2 more sources

Semicarbazide-Sensitive Amine Oxidase (SSAO) and Lysyl Oxidase (LOX) Association in Rat Aortic Vascular Smooth Muscle Cells [PDF]

open access: yesBiomolecules, 2022
Vascular smooth muscle cells (VSMCs) are the main stromal cells in the medial layer of the vascular wall. These cells produce the extracellular matrix (ECM) and are involved in many pathological changes in the vascular wall. Semicarbazide-sensitive amine
Vesna Manasieva   +5 more
doaj   +2 more sources

Zinc-α2-glycoprotein as an inhibitor of amine oxidase copper-containing 3 [PDF]

open access: yesOpen Biology, 2020
Zinc-α2-glycoprotein (ZAG) is a major plasma protein whose levels increase in chronic energy-demanding diseases and thus serves as an important clinical biomarker in the diagnosis and prognosis of the development of cachexia.
Matthias Romauch
doaj   +2 more sources

Methylxanthines Inhibit Primary Amine Oxidase and Monoamine Oxidase Activities of Human Adipose Tissue [PDF]

open access: yesMedicines, 2020
Background: Methylxanthines including caffeine and theobromine are widely consumed compounds and were recently shown to interact with bovine copper-containing amine oxidase.
Wiem Haj Ahmed   +8 more
doaj   +2 more sources

HPLC–UV assay for the evaluation of inhibitors of plasma amine oxidase using crude bovine plasma [PDF]

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2019
Recently, we have described a method for evaluation of plasma amine oxidase (PAO) inhibitors, which monitors the formation of 6-(5-phenyl-2H-tetrazol-2-yl)hexanal from the corresponding amine substrate by HPLC with UV-detection using purified bovine PAO.
Kira Mergemeier   +2 more
doaj   +2 more sources

Amine oxidase copper-containing 3 (AOC3) inhibition: a potential novel target for the management of diabetic retinopathy [PDF]

open access: yesInternational Journal of Retina and Vitreous, 2021
Background Diabetic retinopathy (DR), a microvascular complication of diabetes, is the leading cause of visual impairment in people aged 20–65 years and can go undetected until vision is irreversibly lost.
David S. Boyer   +5 more
doaj   +2 more sources

Hydralazine Attenuates Lipopolysaccharide-Induced Murine Myocardial Dysfunction by Inhibition of Semicarbazide-Sensitive Amine Oxidase [PDF]

open access: yesAntioxidants
Sepsis-induced myocardial dysfunction (SIMD) is a fatal complication with limited therapeutic options. Semicarbazide-sensitive amine oxidase (SSAO) contributes to oxidative stress and leukocyte recruitment, yet its role in SIMD remains unexplored.
Zejian Kuang   +5 more
doaj   +2 more sources

Hansenula polymorpha: An attractive model organism for molecular studies of peroxisome biogenesis and function [PDF]

open access: yes, 1992
In wild-type Hansenula polymorpha the proliferation of peroxisomes is induced by various unconventional carbon- and nitrogen sources. Highest induction levels, up to 80% of the cytoplasmic volume, are observed in cells grown in methanol-limited chemostat
Harder, W.,   +3 more
core   +13 more sources

Amine oxidases as important agents of pathological processes of rhabdomyolysis in rats [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2016
In this study we have tested an idea on the important role of amine oxidases (semicarbazide-sensitive amine oxidase, diamine oxidase, polyamine oxidase) as an additional source of oxidative/carbonyl stress under glycerol-induced rhabdomyolysis, since the
O. O. Gudkova   +2 more
doaj   +1 more source

Properties of a cryptic lysyl oxidase from haloarchaeon Haloterrigena turkmenica [PDF]

open access: yesPeerJ, 2019
Background Lysyl oxidases (LOX) have been extensively studied in mammals, whereas properties and functions of recently found homologues in prokaryotic genomes remain enigmatic. Methods LOX open reading frame was cloned from Haloterrigena turkmenica in an
Nikolay B. Pestov   +6 more
doaj   +2 more sources

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