Results 271 to 280 of about 71,396 (331)

Characterization of the Preprocessed Copper Site Equilibrium in Amine Oxidase and Assignment of the Reactive Copper Site in Topaquinone Biogenesis

open access: green, 2019
Charles N. Adelson   +9 more
openalex   +2 more sources

Deciphering Pigmented Rice Varieties as Sustainable and Unexplored Valuable Sources of Bioactive Components With Health‐Related Properties and Technological Applications—A Systematic Review

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT The interest in pigmented grains has grown substantially in recent years. Pigmented rice is crucial for diversifying agricultural production and promoting healthier, more balanced diets. This systematic review updates and discusses literature published between 2019 and 2024 on the bioactive compounds in pigmented rice, their potential health ...
Adolfo Pinheiro de Oliveira   +2 more
wiley   +1 more source

Competition between binding partners of yeast Pex3 affects peroxisome biology

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 175-195, January 2026.
Pex3 is a peroxisomal membrane protein (PMP) that specifically recruits several binding partners. In the yeast Hansenula polymorpha, Atg30 (pexophagy), Inp1 (inheritance) and Pex19 (receptor for new PMPs) associate with Pex3. Overexpression of any of these proteins affects peroxisomal processes because these proteins compete for binding to Pex3.
Eline M. F. de Lange   +5 more
wiley   +1 more source

A guide to building the matrisome interactome: from computational predictions to experimental validation

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 42-70, January 2026.
This guide proposes a roadmap combining state‐of‐the‐art computational and experimental approaches (including biophysical, biochemical, and imaging techniques) to identify, characterize, and contextualize extracellular matrix (ECM) protein interactions.
Leanna Leverton   +4 more
wiley   +1 more source

Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale

open access: yesGeriatrics &Gerontology International, Volume 26, Issue 1, January 2026.
ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi   +4 more
wiley   +1 more source

Comparative Investigation of Cytotoxic Effects of Structurally Diverse Small Molecules and In Silico Analysis of 1‐Acetyl‐4‐(4‐Hydroxyphenyl)piperazine

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT This study assessed the anticancer activity of boron‐containing and structurally diverse small molecules in 4T1 breast cancer and Caco‐2 colon adenocarcinoma cells. Initial screening showed that five boronic acids lacked significant cytotoxicity, underscoring the structural specificity required for boron‐mediated bioactivity.
Azmi Yerlikaya   +2 more
wiley   +1 more source

Quantitative Treatments for Explaining the Mechanism and Kinetics of Catalytic Electron Transfers in Murburn Processes, Particularly Involving Heme Enzymes Like (Per)oxidases and P450s

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
The seminal Michaelis–Menten theorization for biological catalysis was based on “transition state” (TS), involving the formation of a topologically complementary substrate (S) and enzyme (E) complex (ES) at the “active site” of the latter. Rudolph Marcus put forth the theory of outer sphere electron transfer (ET) in a “donor–acceptor” TS complex, which
Kelath Murali Manoj   +4 more
wiley   +1 more source

Amine oxidase inhibitors

Progress in Cardiovascular Diseases, 1960
Several years ago it was observed that iproniazid (nicotinic isopropylhydrazide) used in the treatment of tuberculous patients produced a euphoria in those who were depressed. This chance observation opened a whole realm of study. Iproniazid is now recognized not only as an antibiotic but as one of a large class of psychostimulant or psychoenergizers ...
  +5 more sources

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