Results 91 to 100 of about 3,229,837 (311)

The d-amino acid oxidase of Neurospora [PDF]

open access: yes, 1944
Among artificially produced mutants of the mold Neurospora have been found strains lacking the ability to synthesize specific amino acids (1, 2). In the course of biochemical and genetic studies of this group of mutants it was observed that some of the ...
Horowitz, N. H.
core  

Determination Of Amino Acid Composition Of Broсcoli Cabbage Protein [PDF]

open access: yes, 2018
A wide range of fresh fruits and vegetables grown in different geographical areas and represented in International trade networks has changed the consumers' approaches to their choice.
Belinska, S. (Svitlana)   +3 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Oxidant-Mediated Protein Amino Acid Conversion

open access: yesAntioxidants, 2019
Biological oxidation plays important roles in the pathogenesis of various diseases and aging. Carbonylation is one mode of protein oxidation. It has been reported that amino acids that are susceptible to carbonylation are arginine (Arg), proline (Pro ...
Yuichiro J. Suzuki
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Editorial: Exploring and expanding the protein universe with non-canonical amino acids

open access: yesFrontiers in Molecular Biosciences, 2023
Gustavo Fuertes   +2 more
doaj   +1 more source

The L-amino acid oxidase of Neurospora [PDF]

open access: yes, 1951
In 1944 one of us described a D-amino acid oxidase in extracts of Neurospora crassa (1). Except for slight activity against L-glutamate, no oxidation of L-amino acids was observed.
Horowitz, N. H., Thayer, Philip S.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Lysosomal Amino Acid Efflux Assay

open access: yesBio-Protocol, 2014
As the cellular “recycling” organelle, lysosomes break down proteins into amino acids, which are then transported into cytosol for reuse by various amino acid transporters.
Chunlei Cang, Dejian Ren
doaj   +1 more source

Seasonal Response of Workers of the Allegheny Mound Ant, \u3ci\u3eFormica Exsectoides\u3c/i\u3e (Hymenoptera: Formicidae) to Artificial Honeydews of Varying Nutritional Content [PDF]

open access: yes, 2018
Field colonies of Allegheny mound ants, Formica exsectoides, were tested at monthly intervals throughout the summer to assess their preference for artificial honeydews containing varying compositions of sugars and amino acids.
Bristow, C. M, Yanity, E.
core   +2 more sources

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