Results 181 to 190 of about 9,329,573 (350)

Amino Acid Nutrition in Poultry: A Review. [PDF]

Animals (Basel)
Alabi T, Adedokun S.
europepmc   +1 more source

Branched-chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control

Nature Metabolism, 2019
S. Solon-Biet, V. Cogger, T. Pulpitel, Devin Wahl, Ximonie Clark, Elena E Bagley, Gabrielle C Gregoriou, A. Senior, Qiao-Ping Wang, A. Brandon, Ruth Perks, J. O’Sullivan, Y. Koay, K. Bell‐Anderson, M. Kebede, Belinda Yau, Clare Atkinson, G. Svineng, Tim Dodgson, J. A. Wali, M. Piper, Paula Juricic, L. Partridge, A. Rose, D. Raubenheimer, G. Cooney, D. L. Le Couteur, S. Simpson   +27 more
semanticscholar   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Rethinking dynamics: static amino acid PET parameters vs. dynamic amino acid PET parameters for the detection of tumor progression in patients with post-treatment glioma. [PDF]

Front Nucl Med
Henssen D, Rullmann M, Schildan A, Striepe S, Schürer M, Scherlach C, Jähne K, Stassart R, Sabri O, Seidel C, Hesse S.   +10 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Molecular Complexity Constrained Early Amino Acid Recruitment into the Genetic Code. [PDF]

Genome Biol Evol
Hashmi SA, Chok H, Cabrera R, Blanco C.
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

5‑Amino-5-deoxyshikimic Acid as a Versatile γ‑Amino Acid for Peptidomimetic Synthesis. [PDF]

ACS Omega
Suć Sajko J, Pahović F, Jerić I.
europepmc   +1 more source

Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

Science, 2017
Monther Abu-Remaileh, Gregory A. Wyant, Choah Kim, N. N. Laqtom, M. Abbasi, Sze Ham Chan, Elizaveta Freinkman, D. Sabatini   +7 more
semanticscholar   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source