Results 221 to 230 of about 3,446,513 (355)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Editorial: Aromatic Amino Acid Metabolism

Frontiers in Molecular Biosciences, 2019
Qian Han, Robert S. Phillips, Jianyong Li   +2 more
doaj   +1 more source

A key amino acid site associated with rhodopsin mammal evolution to diurnal vision. [PDF]

Sci Rep
Fernández-Sampedro MA, Ramon E, Aguileta G, Bosch-Presegué L, Garriga P.   +4 more
europepmc   +1 more source

Helical l –Leu‐Based Peptides Having Chiral Five‐Membered Carbocyclic Ring Amino Acids with an Ethylene Acetal Moiety

, 2017
Yurie Koba, Atsushi Ueda, Makoto Oba, Mitsunobu Doi, Yosuke Demizu, Masaaki Kurihara, Masakazu Tanaka   +6 more
openalex   +2 more sources

Potential effects of supplementation with amino acids, choline or sialic acid on cognitive development in young infants [PDF]

, 2003
Colombo J-P, C Garcia-Rodenas, Guesry PR, Rey J   +3 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Amino acid metabolic reprogramming drives pathogenesis and therapy in hematologic malignancies. [PDF]

Discov Oncol
Ren D, Liu R, Li W, Li L, Lv X, Xia X, Lei X.   +6 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Protein activities driven by amino acid composition. [PDF]

J Biol Chem
Cascarina SM, Ross ED.
europepmc   +1 more source

Designing better diffracting crystals of biotin carboxyl carrier protein fromPyrococcus horikoshiiby a mutation based on the crystal-packing propensity of amino acids [PDF]

, 2017
Kazunori Yamada, N. Kunishima, Yoshinori Matsuura, K. Nakai, Hisashi Naitow, Yoshinori Fukasawa, Kentaro Tomii   +6 more
openalex   +1 more source