Results 251 to 260 of about 1,017,471 (305)

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Laser‐Based Sculpturing of Embedded Ultrathin Metal‐Oxide Nanopores for Enhanced Biomolecular Sensing

open access: yesAdvanced Functional Materials, EarlyView.
Controlled laser‐drilling of embedded HfO2 membranes creates three layer nanopores with Gaussian‐shaped cavities sculptured in the supporting layers. These embedded solid‐state nanopores slow DNA translocation by 12‐fold compared to SiNx pores, enabling high‐resolution, label‐free detection of short DNAs, RNAs, and proteins.
Jostine Joby   +4 more
wiley   +1 more source
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Amino acid compositions of proteinoids

Archives of Biochemistry and Biophysics, 1963
Abstract Proteinoids prepared by thermal copolymerization of 18 common amino acids have been analyzed. Conditions for quantitative recovery of the total amino acids following hydrolysis have been established. The effects of various amino acid reaction mixtures upon the composition of the polymers obtained have been studied.
S W, FOX   +3 more
openaire   +2 more sources

Amino-acid Composition of Crotoxin

Nature, 1951
THE first snake-venom prepared in the pure crystalline form was crotoxin from Crotalus terr. terr. as described in 1938; at that time only its cystine and methionine contents were quantitatively determined1. This protein, with a molecular weight of 30,0002, proved to be homogeneous3 in the ultra-centrifuge2 as well as by electrophoresis4.
K H, SLOTTA, J, PRIMOSIGH
openaire   +2 more sources

Amino-Acid Composition of Salmine

Nature, 1949
A DETAILED chemical analysis of the amino-acid composition of salmine (from a commercial source) was presented by Block and Boiling1, who used chemical and microbiological techniques. The amino-acids found were arginine, alanine, isoleucine, proline, serine and valine. Tristram2 confirmed the presence of these, and in addition demonstrated that glycine
D, HAMER, D L, WOODHOUSE
openaire   +2 more sources

Amino acid composition of mycobacteria

Archives of Biochemistry and Biophysics, 1956
Abstract The amino acid composition of ten strains of mycobacteria cultured on chemically defined media has been determined by microbiological assay. It was found that glutamic acid is the most abundant amino acid, and that the relative order of abundance of the other amino acids differs somewhat from that of other microorganisms or vertebrates ...
B, GINSBURG, S L, LOVETT, M S, DUNN
openaire   +2 more sources

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