Results 71 to 80 of about 5,782,728 (313)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

THE AMINO ACID COMPOSITION OF CRYSTALLINE PEPSIN [PDF]

open access: yesThe Journal of General Physiology, 1959
The amino acid composition of twice recrystallized pepsin (Worthington Biochemical Corporation) has been determined chromatographically on columns of Amberlite IR 120 resin. The results of the analyses obtained on four different preparations indicate a close agreement in their amino acid composition. Pepsin is unique in that it has a great predominance
O O, BLUMENFELD, G E, PERLMANN
openaire   +2 more sources

Amino acid composition and conservation in three potential motifs.

open access: yes, 2023
Amino acid composition and conservation in three potential motifs.
Chen Song (216175)   +7 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Effect of Processing Methods on Amino Acid and Fatty Acid Composition of Parkia biglobosa Seeds

open access: yesApplied Sciences
Parkia biglobosa (PB) is among the various underexploited nutritious plants. A comparative study was conducted on the effect processing PB has on the amino and fatty acid composition.
Foluso Oluwagbemiga Osunsanmi   +4 more
doaj   +1 more source

Amino Acid Composition of Thymus Nucleohistone.

open access: yesExperimental Biology and Medicine, 1953
Summary1. Two samples of histone isolated from bovine thymus nuclei have been analyzed for their content of 18 amino acids by microbiological methods. Approximately 98% of the total N of the protein was accounted for by 16 amino acids. 2. Xo tryptophan was found in the thymus nucleohistone samples. 3.
M D, MORRIS, H A, HARPER
openaire   +2 more sources

Effect of oxygen tension on the amino acid utilisation of human embryonic stem cells

open access: yes, 2014
Background/aims: human embryonic stem cells (hESCs) are a potential source of cells for treatment of many degenerative diseases, but in culture have a propensity to spontaneously differentiate, possibly due to suboptimal conditions. Culture at low oxygen
Christensen, David R.   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Dietary glutamine modulates egg albumen and yolk composition in laying quails: effects of age

open access: yesPoultry Science
This study evaluated the effects of dietary l -glutamine (Gln) supplementation on egg composition and amino acid profiles in laying Japanese quail (Coturnix japonica). A total of 320 birds were assigned to four dietary treatments containing 0.0%, 0.5%, 1.
Ewa Tomaszewska   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy