Results 191 to 200 of about 224,227 (220)
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 1987
The transport of glycine and L-lysine into murine P388 leukemia cells has been examined. Glycine transport appears to be shared by both systems A and ASC in P388 cells. Glycine transport is Na+-dependent and is effectively blocked by alpha-(methylamino)isobutyric acid, threonine and alanine but only a marginal reduction in transport is seen with 100 ...
P, Lazarus, L C, Panasci
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The transport of glycine and L-lysine into murine P388 leukemia cells has been examined. Glycine transport appears to be shared by both systems A and ASC in P388 cells. Glycine transport is Na+-dependent and is effectively blocked by alpha-(methylamino)isobutyric acid, threonine and alanine but only a marginal reduction in transport is seen with 100 ...
P, Lazarus, L C, Panasci
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Journal of Cellular Physiology, 1993
AbstractThe uptake of L‐leucine and L‐lysine into vascular smooth muscle cells cultured from the aortas of rats has been investigated. Both amino acids are taken up by saturable systems that are independent of the presence of a ·Na+ gradient and can be stimulated in trans by neutral bulky amino acids for leucine and cationic amino acids for lysine ...
B C, Low, I K, Ross, M R, Grigor
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AbstractThe uptake of L‐leucine and L‐lysine into vascular smooth muscle cells cultured from the aortas of rats has been investigated. Both amino acids are taken up by saturable systems that are independent of the presence of a ·Na+ gradient and can be stimulated in trans by neutral bulky amino acids for leucine and cationic amino acids for lysine ...
B C, Low, I K, Ross, M R, Grigor
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Biochemistry, 1993
Two-microelectrode voltage clamp was used to measure membrane currents resulting from flux of cationic amino acids in Xenopus oocytes expressing the cloned dual-function ecotropic murine leukemia virus receptor/system y+ transporter. At membrane potentials ranging from +20 mV to -120 mV, arginine influx obeyed Michaelis-Menten kinetics.
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Two-microelectrode voltage clamp was used to measure membrane currents resulting from flux of cationic amino acids in Xenopus oocytes expressing the cloned dual-function ecotropic murine leukemia virus receptor/system y+ transporter. At membrane potentials ranging from +20 mV to -120 mV, arginine influx obeyed Michaelis-Menten kinetics.
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Journal of Membrane Biology, 2001
The functional properties of the transport of lysine across the chicken erythrocyte membrane were investigated. The animal population studied (male Leghorn chickens, 6-14 weeks old) was found to consist of two groups presenting either low (LT, 19 individuals) or high transport rates (HT, 20 individuals).
M, Vargas, R, Devés
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The functional properties of the transport of lysine across the chicken erythrocyte membrane were investigated. The animal population studied (male Leghorn chickens, 6-14 weeks old) was found to consist of two groups presenting either low (LT, 19 individuals) or high transport rates (HT, 20 individuals).
M, Vargas, R, Devés
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The FASEB Journal, 2005
ABSTRACT The transport of arginine has been characterized in human airway Calu‐3 cells. As assessed with RT‐PCR, Calu‐3 cells express the genes for several transporters, such as the system y + ‐related SLC7A1, SLC7A2 , and
ROTOLI, Bianca Maria +4 more
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ABSTRACT The transport of arginine has been characterized in human airway Calu‐3 cells. As assessed with RT‐PCR, Calu‐3 cells express the genes for several transporters, such as the system y + ‐related SLC7A1, SLC7A2 , and
ROTOLI, Bianca Maria +4 more
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Pfl�gers Archiv European Journal of Physiology, 1992
Lysine influx (2 microM) into activated human B and T lymphocytes through transport systems y+ and y+L was measured. In activated T cells very substantial activation of system y+ was detected; system y+L was also activated in these cells but with a slower time course and to a smaller extent.
C A, Boyd, D H, Crawford
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Lysine influx (2 microM) into activated human B and T lymphocytes through transport systems y+ and y+L was measured. In activated T cells very substantial activation of system y+ was detected; system y+L was also activated in these cells but with a slower time course and to a smaller extent.
C A, Boyd, D H, Crawford
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 1991
Transport systems y+, asc and ASC exhibit dual interactions with dibasic and neutral amino acids. For conventional Na(+)-dependent neutral amino acid system ASC, side chain amino and guanido groups bind to the Na+ site on the transporter. The topographically equivalent recognition site on related system asc binds harmaline (a Na(+)-site inhibitor) with
J D, Young, D A, Fincham, C M, Harvey
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Transport systems y+, asc and ASC exhibit dual interactions with dibasic and neutral amino acids. For conventional Na(+)-dependent neutral amino acid system ASC, side chain amino and guanido groups bind to the Na+ site on the transporter. The topographically equivalent recognition site on related system asc binds harmaline (a Na(+)-site inhibitor) with
J D, Young, D A, Fincham, C M, Harvey
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Biochemistry, 1995
Injection of mRNA isolated from human placental choriocarcinoma cells (JAR) into Xenopus laevis oocytes induced the transport of the neutral amino acid leucine as well as the transport of the cationic amino acid arginine. The induced transport of leucine was predominantly Na(+)-dependent, whereas that of arginine was Na(+)-independent.
Y J, Fei +3 more
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Injection of mRNA isolated from human placental choriocarcinoma cells (JAR) into Xenopus laevis oocytes induced the transport of the neutral amino acid leucine as well as the transport of the cationic amino acid arginine. The induced transport of leucine was predominantly Na(+)-dependent, whereas that of arginine was Na(+)-independent.
Y J, Fei +3 more
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Nephron Experimental Nephrology, 2007
<i>Background:</i> Nitric oxide (NO), a key endogenous mediator involved in the maintenance of platelet function, is synthesized from the amino acid <i>L</i>-arginine. We have shown that <i>L</i>-arginine transport in platelets is rate-limiting for NO synthesis.
Mariana Alves de Sá Siqueira +7 more
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<i>Background:</i> Nitric oxide (NO), a key endogenous mediator involved in the maintenance of platelet function, is synthesized from the amino acid <i>L</i>-arginine. We have shown that <i>L</i>-arginine transport in platelets is rate-limiting for NO synthesis.
Mariana Alves de Sá Siqueira +7 more
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Nephron. Experimental nephrology, 2008
Nitric oxide (NO), a key endogenous mediator involved in the maintenance of platelet function, is synthesized from the amino acid L-arginine. We have shown that L-arginine transport in platelets is rate-limiting for NO synthesis. A disturbance in the L-arginine-NO pathway in platelets was previously described in chronic renal failure (CRF) patients ...
Siqueira, M A D +7 more
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Nitric oxide (NO), a key endogenous mediator involved in the maintenance of platelet function, is synthesized from the amino acid L-arginine. We have shown that L-arginine transport in platelets is rate-limiting for NO synthesis. A disturbance in the L-arginine-NO pathway in platelets was previously described in chronic renal failure (CRF) patients ...
Siqueira, M A D +7 more
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