Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II [PDF]
, 2005 MCoTl-I and MCoTl-II from the seeds of Momordica cochinchinensis are inhibitors of trypsin-like proteases and the only known members of the large family of squash inhibitors that are cyclic and contain an additional loop connecting the amino- and the ...
Avrutina, Olga +6 more
core +1 more source
A micromethod for the determination of glycocyamine in biological fluids and tissue extracts [PDF]
, 1941 In the two following communications (1, 2) evidence is presented that glycocyamine is a normal precursor of creatine in the animal body. These studies required a satisfactory micromethod for the determination of glycocyamine.
Borsook, Henry, Dubnoff, Jacob W.
core
The cell cycle program of polypeptide labeling in Chlamydomonas reinhardtii [PDF]
, 1977 The cell cycle program of polypeptide labeling in syndhronous cultures of wild-type Chlamydomonas reinhardtii was analyzed by pulse-labeling cells with 35SO4 = or [3H]arginine at different cell cycle stages.
Hill, Kim R. +2 more
core +5 more sources
Signaling from blood vessels to CNS axons through nitric oxide [PDF]
, 2006 Brain function is usually perceived as being performed by neurons with the support of glial cells, the network of blood vessels situated nearby serving simply to provide nutrient and to dispose of metabolic waste.
Bartus, K +6 more
core +1 more source
Efficacy and Mechanism EvaluationBackground Nutrition is essential for preterm brain development. Optimal nutrition is dependent upon gastrointestinal health. Primary objective To form a multiprofessional collaboration to design the world’s first neonatal precision-medicine platform ...
Neena Modi +17 more
doaj +1 more source
Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancer. [PDF]
, 2014 BackgroundPancreatic ductal adenocarcinoma has proven to be one of the most chemo-resistant among all solid organ malignancies. Several mechanisms of resistance have been described, though few reports of strategies to overcome this chemo-resistance have ...
Bold, Richard J +3 more
core +2 more sources
Vascular Function Intervention Trial in sickle cell disease (V-FIT): Trial Protocol [PDF]
, 2014 This protocol outlines procedures for capturing participant information as part of the V-FIT study. The protocol should not be used as a guide for the treatment of other participants; every care was taken in its drafting, but corrections or amendments ...
Cox, Sharon +3 more
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The hydrolysis of N-benzoyl-L-argininamide by crystalline trypsin [PDF]
, 1949 A reinvestigation of the kinetics of hydrolysis of N-benzoyl-n-argininamide by crystalline trypsin has led to the conclusion that the hydrolysis products enter into the over-all reaction as ...
Harmon, Kent M., Niemann, Carl
core
Mitochondria and neuroprotection in stroke: Cationic arginine-rich peptides (CARPs) as a novel class of mitochondria-targeted neuroprotective therapeutics [PDF]
, 2018 Stroke is the second leading cause of death globally and represents a major cause of devastating long-term disability. Despite sustained efforts to develop clinically effective neuroprotective therapies, presently there is no clinically available ...
Anderton, Ryan S +4 more
core +1 more source
Proteomic analysis of cortical neuronal cultures treated with poly-arginine peptide-18 (R18) and exposed to glutamic acid excitotoxicity [PDF]
, 2019 Poly-arginine peptide-18 (R18) has recently emerged as a highly effective neuroprotective agent in experimental stroke models, and is particularly efficacious in protecting cortical neurons against glutamic acid excitotoxicity.
Anderton, Ryan S +4 more
core +1 more source