Results 11 to 20 of about 500,496 (206)
Modification of arginine residues using dicarbonyl compounds is a common method to identify functional or reactive arginine residues in proteins.
Jayanta K. Chakrabarty (5900138) +9 more
core +3 more sources
Differential impact of L-arginine deprivation on the activation and effector functions of T cells and macrophages. [PDF]
The metabolism of the amino acid L-arginine is emerging as a crucial mechanism for the regulation of immune responses. Here, we characterized the impact of L-arginine deprivation on T cell and macrophage (MPhi) effector functions: We show that whereas L ...
Corset, C +20 more
core +1 more source
L-arginine deprivation impairs Leishmania major-specific T-cell responses. [PDF]
The amino acid L-arginine plays a crucial role in the regulation of immune responses. We have recently shown that uncontrolled replication of Leishmania parasites at the site of pathology correlates with high levels of arginase activity in nonhealing ...
Markus Munder +7 more
core +1 more source
Bioinformatic evaluation of L-arginine catabolic pathways in 24 cyanobacteria and transcriptional analysis of genes encoding enzymes of L-arginine catabolism in the cyanobacterium Synechocystis sp. PCC 6803 [PDF]
Schriek S, Rückert C, Staiger D, Pistorius EK, Michel K-P. Bioinformatic evaluation of L-arginine catabolic pathways in 24 cyanobacteria and transcriptional analysis of genes encoding enzymes of L-arginine catabolism in the cyanobacterium Synechocystis ...
Klaus-Peter Michel +14 more
core +1 more source
Plasma arginine vasopressin concentrations in epileptics under monotherapy [PDF]
Plasma arginine vasopressin concentrations were determined by radio-immunoassay in 112 adult epileptics who were taking carbamazepine, phenytoin, primidone, or sodium valproate in long-term monotherapy, and in 19 controls.
Rascher, W. +5 more
core +1 more source
Objective: to study the effect of the ursodeoxycholic acid and L-arginine combination on the background of basic therapy on the structural and functional state of the heart and indicators of the autonomic nervous system in patients with coronary heart ...
N. S. Mykhailovska, L. Ye. Miniailenko
doaj +1 more source
Immune metabolic regulation shapes the host-pathogen interaction during infection with Mycobacterium tuberculosis (Mtb), the pathogen of human tuberculosis (TB). Several immunometabolites generated by metabolic remodeling in macrophages are implicated in
Jin Kyung Kim +5 more
doaj +1 more source
Arginine is a dibasic, cationic, semiessential amino acid with numerous roles in cellular metabolism. It serves as an intermediate in the urea cycle and as a precursor for protein, polyamine, creatine and nitric oxide (NO) biosynthesis. Arginine is conditionally essential since it becomes necessary under periods of growth and after recovery after ...
openaire +2 more sources
L-Arginine has attracted major interest because it has been identified as the natural substrate of nitric oxide synthase and is now recognized as a major player in the regulation of biological function. The arginine paradox refers to the phenomenon that exogenous L-arginine causes NO-mediated biological effects despite the fact that nitric oxide ...
NAKAKI, Toshio, HISHIKAWA, Keiichi
openaire +3 more sources
Preclinical evidence of a direct pro-survival role of arginine deprivation in multiple myeloma
Multiple myeloma grows by establishing multiple interactions with bone marrow cells. These include expansion of myeloid-derived suppressor cells, which drive immunoevasion via mechanisms that include arginase-1-driven depletion of L-arginine, thus ...
Matteo Trudu +11 more
doaj +1 more source

