Results 11 to 20 of about 490,412 (303)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant-state stabilization. [PDF]

open access: yesMol Oncol
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
Kwon SH, Lee JM.
europepmc   +2 more sources

Arginine and Immunity [PDF]

open access: yesThe Journal of Nutrition, 2007
For many years, dietary arginine supplementation, often combined with other substances, has been used as a mechanism to boost the immune system. Considerable controversy, however, exists as to the benefits and indications of dietary arginine due in part to a poor understanding of the role played by this amino acid in maintaining immune function ...
Petar J, Popovic   +2 more
openaire   +2 more sources

Bioinformatic evaluation of L-arginine catabolic pathways in 24 cyanobacteria and transcriptional analysis of genes encoding enzymes of L-arginine catabolism in the cyanobacterium Synechocystis sp. PCC 6803 [PDF]

open access: yes, 2007
Schriek S, Rückert C, Staiger D, Pistorius EK, Michel K-P. Bioinformatic evaluation of L-arginine catabolic pathways in 24 cyanobacteria and transcriptional analysis of genes encoding enzymes of L-arginine catabolism in the cyanobacterium Synechocystis ...
Klaus-Peter Michel   +14 more
core   +1 more source

L-arginine deprivation impairs Leishmania major-specific T-cell responses. [PDF]

open access: yes, 2009
The amino acid L-arginine plays a crucial role in the regulation of immune responses. We have recently shown that uncontrolled replication of Leishmania parasites at the site of pathology correlates with high levels of arginase activity in nonhealing ...
Markus Munder   +7 more
core   +1 more source

Plasma arginine vasopressin concentrations in epileptics under monotherapy [PDF]

open access: yes, 1983
Plasma arginine vasopressin concentrations were determined by radio-immunoassay in 112 adult epileptics who were taking carbamazepine, phenytoin, primidone, or sodium valproate in long-term monotherapy, and in 19 controls.
Rascher, W.   +5 more
core   +1 more source

Differential impact of L-arginine deprivation on the activation and effector functions of T cells and macrophages. [PDF]

open access: yes, 2008
The metabolism of the amino acid L-arginine is emerging as a crucial mechanism for the regulation of immune responses. Here, we characterized the impact of L-arginine deprivation on T cell and macrophage (MPhi) effector functions: We show that whereas L ...
Corset, C   +20 more
core   +1 more source

The effects of acute arginine supplementation on 10 mile cycling time trial performance in young adult males [PDF]

open access: yes, 2012
L-arginine is one of the most metabolically versatile amino acids in the human body, most notably serving as the pre-cursor for the biosynthesis of nitric oxide (NO).
Gill, Sam
core   +2 more sources

Arginine-Selective Chemical Labeling Approach for Identification and Enrichment of Reactive Arginine Residues in Proteins

open access: yes, 2018
Modification of arginine residues using dicarbonyl compounds is a common method to identify functional or reactive arginine residues in proteins.
Jayanta K. Chakrabarty (5900138)   +9 more
core   +3 more sources

The arginine paradox.

open access: yesFolia Pharmacologica Japonica, 2002
L-Arginine has attracted major interest because it has been identified as the natural substrate of nitric oxide synthase and is now recognized as a major player in the regulation of biological function. The arginine paradox refers to the phenomenon that exogenous L-arginine causes NO-mediated biological effects despite the fact that nitric oxide ...
NAKAKI, Toshio, HISHIKAWA, Keiichi
openaire   +3 more sources

Arginine and Cancer [PDF]

open access: yesThe Journal of Nutrition, 2004
Arginine is a dibasic, cationic, semiessential amino acid with numerous roles in cellular metabolism. It serves as an intermediate in the urea cycle and as a precursor for protein, polyamine, creatine and nitric oxide (NO) biosynthesis. Arginine is conditionally essential since it becomes necessary under periods of growth and after recovery after ...
openaire   +2 more sources

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