Results 31 to 40 of about 388,707 (260)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Arginine-Mediated Liver Immune Regulation and Antioxidant Defense in Largemouth Bass (Micropterus salmoides): Multi-Omics Insights into Metabolic Remodeling During Nocardia seriolae Infection

Antioxidants
The liver of fish is an essential metabolic organ that also serves an immune regulatory role. In this study, we constructed a model of largemouth bass (Micropterus salmoides) infected with Nocardia seriolae by injection to explore the immune and ...
Yu-Long Sun, Shuai-Liang Zhang, Feng-Feng Zhou, Yuan-Xin Qian, Yang He, Run-Zhe Zhang, Fen Dong, Qiang Chen, Han-Ying Xu, Ji-Teng Wang, Yu-Ting Deng, Tao Han   +11 more
doaj   +1 more source

Cationic Arginine-Rich Peptides (CARPs): A Novel Class of Neuroprotective Agents With a Multimodal Mechanism of Action

Frontiers in Neurology, 2020
There are virtually no clinically available neuroprotective drugs for the treatment of acute and chronic neurological disorders, hence there is an urgent need for the development of new neuroprotective molecules.
Bruno P. Meloni, Bruno P. Meloni, Bruno P. Meloni, Frank L. Mastaglia, Frank L. Mastaglia, Neville W. Knuckey, Neville W. Knuckey, Neville W. Knuckey   +7 more
doaj   +1 more source

Arginine Requirement and the Arginine Content of Casein

Poultry Science, 1964
Abstract Much has been written concerning the high arginine requirement of chicks fed diets based on casein as the source of protein. The peculiar amino acid balance of casein, as suggested by studies from this laboratory (Fisher, Shapiro and Griminger, 1960), may in part explain this phenomenon. We now wish to draw attention to a recently published
H. Fisher, P. Griminger
openaire   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Arginine inhibits cross-kingdom interactions and synergistic cariogenicity between Streptococcus mutans and Candida albicans

Frontiers in Cellular and Infection Microbiology
IntroductionStreptococcus mutans and Candida albicans are common pathogenic organisms from the oral microbial community, and are associated with the pathogenesis of caries.
Hong-yu Gao, Hao Yang, Hong-mei Wang, Hao-ming Li, Yan-song Ma, Yu-xing Bai   +5 more
doaj   +1 more source

Amino Acids As Mediators of Metabolic Cross Talk between Host and Pathogen

Frontiers in Immunology, 2018
The interaction between host and pathogen decidedly shapes the outcome of an infection, thus understanding this interaction is critical to the treatment of a pathogen-induced infection.
Wenkai Ren, Wenkai Ren, Ranjith Rajendran, Yuanyuan Zhao, Bie Tan, Guoyao Wu, Fuller W. Bazer, Guoqiang Zhu, Yuanyi Peng, Xiaoshan Huang, Jinping Deng, Yulong Yin   +11 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Myofibrillar Protein Profile of the Breast Muscle in Turkeys as a Response to the Variable Ratio of Limiting Amino Acids in Feed

Agriculture
The effects of the different dietary levels of Arginine (Arg) in low- and high-methionine (Met) diets on the meat quality and myofibrillar protein profile of breast muscles from turkeys were determined.
Paweł Konieczka, Wiesław Przybylski, Danuta Jaworska, Elżbieta Żelechowska, Piotr Sałek, Dominika Szkopek, Aleksandra Drażbo, Krzysztof Kozłowski, Jan Jankowski   +8 more
doaj   +1 more source

Arginine 37 of Glycine Linker Dictates Regulatory Function of HapR

Frontiers in Microbiology, 2020
HapR is designated as a high cell density quorum sensing master regulatory protein of Vibrio cholerae. It is a member of the TetR family protein and functions both as an activator and a repressor by directly communicating with cognate promoters, thus ...
Manjula Ekka, Abhisek Mondal, Richa Singh, Himanshu Sen, Saumen Datta, Saumya Raychaudhuri   +5 more
doaj   +1 more source