Background: Pyridoxine-dependent epilepsy (PDE) is identified as a rare neurometabolic disease marked by biallelic pathogenic mutations of the ALDH7A1 gene.
Ali Jafari +5 more
doaj +1 more source
Antimicrobial activity of many AMPs can be improved by lysine-to-arginine substitution due to a more favourable interaction of arginine guanidinium moiety with bacterial membranes.
Bruna Agrillo +14 more
doaj +1 more source
Non-equivalence of key positively charged residues of the free fatty acid 2 receptor in the recognition and function of agonist versus antagonist ligands [PDF]
Short chain fatty acids (SCFAs) are produced in the gut by bacterial fermentation of poorly digested carbohydrates. A key mediator of their actions is the G protein-coupled Free Fatty Acid 2 (FFA2) receptor and this has been suggested as a therapeutic ...
Hansen, Anders Højgaard +6 more
core +2 more sources
Anti-atherosclerotic and cardiovascular protective benefits of Brazilian nuts
Brazil nuts are rich in magnesium, selenium, arginine and other amino acids, dietary fiber, tocopherols (vitamin E), phytosterols, linoleic acid, linolenic acid, sitosterols, monounsaturated and polyunsaturated fatty acids, polyphenols and other amino ...
Carlos K B Ferrari
doaj +1 more source
Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome [PDF]
Objective: Previous studies have shown the importance of somatic mutations and arginine residues in the complementarity-determining regions (CDRs) of pathogenic anti-double-stranded DNA (anti-dsDNA) antibodies in human and murine lupus, and in studies of
Giles, I. +7 more
core +1 more source
On the Prediction of In Vitro Arginine Glycation of Short Peptides Using Artificial Neural Networks
One of the hallmarks of diabetes is an increased modification of cellular proteins. The most prominent type of modification stems from the reaction of methylglyoxal with arginine and lysine residues, leading to structural and functional impairments of ...
Ulices Que-Salinas +4 more
doaj +1 more source
EFFECT OF INOCLATION LOCAL AND COMMERCIAL CHICKEN EGGS WITH ARGININE AMINO ACID ON THE DEVELOPMENT OF BURSA OF FABRICIUS [PDF]
The present study emphasizes the importance of in Ovo feeding strategies, particularly the supplementation of fertilized eggs with amino acids such as L-arginine to enhance the Bursa of Fabricius development.
Shangaberry Aziz +5 more
doaj +1 more source
Effect of Basic Amino Acids on Folic Acid Solubility
To prevent neural tube defects and other cardiovascular diseases in newborns, folic acid (FA) is recommended in pregnant women. A daily dose of 600 µg FA consumption is widely prescribed for women during pregnancy and 400 µg for women with childbearing ...
Karen Pérez-Carreón +5 more
doaj +1 more source
A micromethod for the determination of arginine [PDF]
Micromethods for the determination of arginine based on the use of the Sakaguchi reagent have been described (14). This reagent gives a strong color with glycocyamine, arginine, and other monosubstituted guanidine derivatives.
Dubnoff, Jacob W.
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

