Results 11 to 20 of about 43,145,716 (262)

Systems biology of the qa gene cluster in Neurospora crassa. [PDF]

PLoS ONE, 2011
An ensemble of genetic networks that describe how the model fungal system, Neurospora crassa, utilizes quinic acid (QA) as a sole carbon source has been identified previously.
Xiaojia Tang, Wubei Dong, James Griffith, Roger Nilsen, Allison Matthes, Kevin B Cheng, Jaxk Reeves, H-Bernd Schuttler, Mary E Case, Jonathan Arnold, David A Logan   +10 more
doaj   +1 more source

L-arginine attenuates Interleukin-1β (IL-1β) induced Nuclear Factor Kappa-Beta (NF-κB) activation in Caco-2 cells. [PDF]

PLoS ONE, 2017
BACKGROUND:Specific nutrients like L-arginine (L-Arg) ameliorate intestinal inflammation, however the exact mechanisms of this effect are unclear. We hypothesized the anti-inflammatory effects of L-Arg require active transport and metabolism by inducible
Qinghe Meng, Mitchell Cooney, Natesh Yepuri, Robert N Cooney   +3 more
doaj   +1 more source

The Influence of Branched-Chain Amino Acid Supplementation on Fatigue and Tryptophan Metabolism After Acute and Chronic Exercise in Older Adults: Protocol for a Pilot Randomized Controlled Trial

JMIR Research Protocols, 2023
BackgroundFatigue is a strong predictor of negative health outcomes in older adults. Kynurenine, a metabolite of tryptophan, is strongly associated with fatigue.
Ronna N Robbins, Tiffany Cortes, Jason C O'Connor, Rozmin Jiwani, Monica C Serra   +4 more
doaj   +1 more source

A mutation in amino acid permease AAP6 reduces the amino acid content of the Arabidopsis sieve elements but leaves aphid herbivores unaffected [PDF]

, 2010
The aim of this study was to investigate the role of the amino acid permease gene AAP6 in regulating phloem amino acid composition and then to determine the effects of this altered diet on aphid performance.
Gattolin, S., Gattolin, S, Bale, J.S., Barrett, D.A., Hunt, E., Newbury, John, Pritchard, Jeremy, Hunt, E, Bale, Jeffrey, Pritchard, J., Newbury, Henry, Tseng, H., Tseng, HM, Barrett, DA, Newbury, H. J., Pritchard, J. (Jeremy), Tseng, Hua-Ming, Bale, J. S. (Jeffrey S.), Hunt, E. (Emma), Gattolin, Stefano, Barrett, D. A. (David A.)   +20 more
core   +2 more sources

SLC7A7 is a prognostic biomarker correlated with immune infiltrates in non-small cell lung cancer

Cancer Cell International, 2021
Background SLC7A7 (solute carrier family 7, amino acid transporter light chain, y + L system, member 7) is a critical gene in the regulation of cationic amino acid transport.
Wumin Dai, Jianguo Feng, Xiao Hu, Yongyi Chen, Qing Gu, Wangang Gong, Tingting Feng, Jie Wu   +7 more
doaj   +1 more source

Transport of Amino Acids Across the Blood-Brain Barrier

Frontiers in Physiology, 2020
The blood-brain-barrier (BBB), present in brain capillaries, constitutes an essential barrier mechanism for normal functioning and development of the brain.
Rosa Zaragozá
doaj   +1 more source

The AAP gene family for amino acid permeases contributes to development of the cyst nematode Heterodera schachtii in roots of Arabidopsis [PDF]

, 2013
The beet cyst nematode Heterodera schachtii is able to infect Arabidopsis plants and induce feeding sites in the root. These syncytia are the only source of nutrients for the nematodes throughout their life and are a nutrient sink for the host plant.
Elashry, Abdelnaser, Siddique, Shahid, Koch, Wolfgang, Kreil, David, Okumoto, Sakiko, Bohlmann, Holger   +5 more
core   +1 more source

The catalytic subunit of the system L1 amino acid transporter (Slc7a5) facilitates nutrient signalling in mouse skeletal muscle [PDF]

, 2014
The System L1-type amino acid transporter mediates transport of large neutral amino acids (LNAA) in many mammalian cell-types. LNAA such as leucine are required for full activation of the mTOR-S6K signalling pathway promoting protein synthesis and cell ...
Adel F M Ibrahim, Yun-Bo Shi, Mitchell, Fiona E., Grant English (527945), Peter M Taylor, Taylor Peter M., Poncet, Nadège, Fiona E Mitchell, Ibrahim Adel F. M., English, Grant, J. Simon C Arthur (527946), Nadège Poncet, Victoria A McGuire, Yun-Bo Shi (193634), Arthur J. Simon C, McGuire Victoria A., Adel F. M. Ibrahim (188343), Grant English, Taylor, Peter M., Ibrahim, Adel F. M., Poncet Nadège, Nadège Poncet (527942), Victoria A. McGuire (527944), Peter M. Taylor (527947), McGuire, Victoria A., English Grant, Arthur, J. Simon C; id_orcid, Mitchell Fiona E., Shi Yun-Bo, Fiona E. Mitchell (527943), Shi, Yun-Bo, J Simon C Arthur   +31 more
core   +1 more source

Function of SLC7A7 in T-Cell Acute Lymphoblastic Leukemia

Cellular Physiology and Biochemistry, 2018
Background/Aims: Y+LAT1 protein, encoded by the SLC7A7 gene (a member of the SLC7 family), forms the cationic amino acid transport system y+L (system y+L). This system transports cationic amino acids such as arginine and lysine out of the cell. Arginine,
Xiaohui Ji, Xiaoyun Yang, Nan Wang, Meiyun Kang, Yaping Wang, Liucheng Rong, Yongjun Fang, Yao Xue   +7 more
doaj   +1 more source

Root phloem-specific expression of the plasma membrane amino acid proton co-transporter AAP3 [PDF]

, 2004
Amino acids are regarded as the nitrogen ‘currency’ of plants. Amino acids can be taken up from the soil directly or synthesized from inorganic nitrogen, and then circulated in the plant via phloem and xylem.
Sakiko Okumoto, Leister, D., Frommer, Wolf B., Wolf B. Frommer, Okumoto, Sakiko, FISCHER, Wolf N, Stierhof, York Dieter, Stierhof, Y., Fischer, W., Wolfgang Koch, Koch, W., FROMMER, Wolf B, Mechthild Tegeder, Fischer, Wolf N., Leister, Dario, Wolf N. Fischer, Koch, Wolfgang, Okumoto, S., Tegeder, Mechthild, Dario Leister, Tegeder, M., Biehl, A., York Dieter Stierhof, Alexander Biehl, Biehl, Alexander, Frommer, W.   +25 more
core   +2 more sources