Results 171 to 180 of about 212,752 (309)

Asymmetric synthesis of unnatural L-amino acids using thermophilic aromatic L-amino acid transaminase

, 2006
Aromatic L-amino acid transaminase is an enzyme that is able to transfer the amino group from L-glutamate to unnatural aromatic a-keto acids to generate alpha-ketog luta rate and unnatural aromatic L-amino acids, respectively. Enrichment culture was used
Kim, Byung-Gee, Seo, Joo-Hyun, Cho, Byung-Kwan, Lee, Chang-Soo, Kim, Juhan   +4 more
core  

Localizable Fluorescent Metal Ion Indicators With Tunable Colors

Advanced Science, EarlyView.
A modular platform enables the generation of fluorescent metal ion indicators with tunable emission colors and precise subcellular localization. Conjugation to self‐labeling proteins yields bright, color‐tunable potassium probes that permit wash‐free live‐cell imaging, revealing dynamic potassium efflux in stimulated neurons.
Ming‐Ming Wang, De‐en Sun, Klara Gries, Kai Johnsson   +3 more
wiley   +1 more source

Indole-3-acetic acid production is rare among gut bacteria and reflects OFOR-driven amino acid oxidation in acetogens. [PDF]

Gut Microbes
DeFeo ME, Liu Y, Zhou Z, Higginbottom SK, Dodd D.   +4 more
europepmc   +1 more source

AROMATIC AMINO ACIDS IN THE BRAIN [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1974
openaire   +1 more source

Dynamic Regulation of Supramolecular Chirality in an Amphiphilic Dimeric Macrocycle Through Azobenzene‐Based Photoisomerization

Advanced Science, EarlyView.
A stimuli‐responsive supramolecular system has been rationally designed enabling hierarchical control over supramolecular handedness. This hybrid architecture retains orthogonal host‐guest properties and displays unique amphiphilicity‐directed chiral self‐assembly.
Minzan Zuo, Yi Shi, Xueqi Tian, Tao Zhang, Jianmin Jiao, Yuhong Shen, Yutong Xie, Jianwen Wei, Xiao‐Yu Hu   +8 more
wiley   +1 more source

Increased serum phenylalanine and tyrosine concentration related to inflammation in patients with primary angiitis of the central nervous system. [PDF]

Biochem Biophys Rep
Feng N, Wang-Chang J, Wu F, Su H, Zhao Y, Sun L, Zhao S, Chang H, Li H.   +8 more
europepmc   +1 more source

Selective Recognition of Aromatic Amino Acids by a Molecular Cleft in Water

The development of water-soluble hosts for the selective recognition of aromatic amino acids is highly desirable and may serve as a tool to facilitate drug discovery and enable fabrication of sensors for point-of-care monitoring in the context of ...
Keller, Joël F., Mayor, Marcel, Valášek, Michal   +2 more
core   +1 more source

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source

Aromatic lactic acid production by <i>Bifidobacterium longum</i> subsp. <i>infantis</i> is determined by cell density, substrate availability, and pH <i>in vitro</i>. [PDF]

Appl Environ Microbiol
Plenge TG, Pedersen M, Laursen MF.
europepmc   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source