Results 41 to 50 of about 8,648 (155)

Engineered exosomes improve myocardial cell membrane integrity and heart function in dystrophic cardiomyopathy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Schematic diagram of the manufacturing process of exosomes‐cardiac homing peptide (Exo‐CHP) and its therapeutic effects for Duchenne muscular dystrophy (DMD) cardiomyopathy. Abstract Background Duchenne muscular dystrophy (DMD)‐associated cardiomyopathy is a leading causes of premature death, yet treatment options remain limited.
Qihong Wu, Yiyuan Xue, Kun Zhang, Ke Xu, Ting Xu, Hang Fu, Suming Zhang, Meng Zhang, Ran Sun, Sophelia Hoi Shan Chan, Linyuhan Zhou, Xiaotang Cai, Yingkun Guo, Huayan Xu   +13 more
wiley   +1 more source

Current Insight into Human Ornithine Aminotransferase: A Review

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 8, Page 1431-1441, August 2026.
ABSTRACT Human ornithine aminotransferase (hOAT) is a mitochondrial matrix pyridoxal‐5′‐phosphate enzyme (PLP) that catalyzes the reversible transfer of the δ‐amino group of L‐ornithine (L‐Orn) to α‐ketoglutarate (α‐KG) yielding glutamate‐5‐semialdehyde (GSA) and glutamate. GSA is prone to cyclize to Δ1‐pyrroline‐5‐carboxylate.
Fulvio Floriani, Carla Borri Voltattorni, Riccardo Montioli   +2 more
wiley   +1 more source

OsMYB306‐OsRAV11 Regulates Resistance of Rice to Striped Stem Borer by Modulating Serotonin Biosynthesis

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4951-4965, August 2026.
ABSTRACT Striped stem borer (SSB; Chilo suppressalis Walker) is one of the most destructive pests in rice production. Previous studies have demonstrated that SSB infestation induces transcription of OsT5H (tryptamine‐5‐hydroxylase) and biosynthesis of serotonin, a newly recognised phytohormone, and that disruption of serotonin biosynthesis ...
Jia‐Run Zhang, Long Wang, Yang‐Fan Chen, Xiao‐Hao Guo, Meng Jiang, Yuan‐Yuan Tan, Qing Wang, Qiu Qian, Angharad M. R. Gatehouse, Qing‐Yao Shu   +9 more
wiley   +1 more source

Synthesis and Properties of Cross‐Shaped Donor–Acceptor Dyes: Tunable Emission From Visible to Near‐Infrared in Solution and Solid‐State

European Journal of Organic Chemistry, Volume 29, Issue 27, 17 July 2026.
A comprehensive investigation (synthesis, electrochemistry, photophysics, and theory) of seven new cross‐shaped dyes based on N,N,N’,N’‐tetraphenyl‐1,4‐phenylenediamine cores substituted with different electron‐withdrawing groups, reveals tunable emission properties spanning the visible to near‐infrared range, both in solution and in the solid state ...
Benjamin Mourot, Gabriel Canard, Michel Giorgi, Olivier Siri, Denis Jacquemin, Simon Pascal   +5 more
wiley   +1 more source

Investigating the Inhibitory Properties of Diazo and Pyrazole‐Carboxamide‐Linked Benzenesulfonamides Against Carbonic Anhydrase Isoforms I, II, IX, and XII

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Hybrid diazo‐ and pyrazole‐carboxamide benzenesulfonamides emerge as highly potent and selective inhibitors of tumor‐associated carbonic anhydrases. A 3,4‐dichloro‐substituted derivative achieves sub‐2 nM inhibition of hCA IX and displays promising anticancer activity, revealing a valuable scaffold for the development of next‐generation cancer‐targeted
Suleyman Akocak, Nebih Lolak, Andrea Ammara, Gökçenur Gürbüz, Ibrahim Bozgeyik, Demet Taşdemir, Hamada Hashem, Stefan Bräse, Claudiu T. Supuran   +8 more
wiley   +1 more source

Transamination between ω‐amino acids, α,ω‐diamino acids and pyridoxal phosphate: Formation of aldimines

FEBS Letters, 1976
Der Garabedian, A.M., Der Garabedian, M.A.   +1 more
openaire   +1 more source

EDA Complex-Mediated C(sp³)-H Cross-Dehydrogenative Coupling Enables Synthesis of Noncanonical <i>α</i>,<i>β</i>-Diamino Acids. [PDF]

European J Org Chem
Sachidanandan K, Stenftenagel C, Joshy A, Cluff AM, Laulhé S.   +4 more
europepmc   +1 more source

Construction of Phospholipid-Like Vesicles by Aqueous Aminolysis of Acyl Thioesters With Diamino Acids. [PDF]

Chemistry
Souto-Trinei FA, Lomba-Riego L, Brea RJ.
europepmc   +1 more source

iDeepLC: Chemical Structure Information Yields Improved Retention Time Prediction of Peptides with Unseen Modifications. [PDF]

Anal Chem
Nameni A, Declercq A, Gabriels R, Devreese R, Degroeve S, De Maesschalck A, Dhaenens M, Chiva C, Sabidó E, Martens L, Bouwmeester R.   +10 more
europepmc   +1 more source

Design of Phosphine-Heteroarenesulfonamide Ligands as Dinuclear Silver Catalysts for Enantioselective Construction of α,β-Diamino Acids. [PDF]

J Am Chem Soc
Iizuka Y, Okajima S, Ueno Y, Takehara T, Suzuki T, Maeda S, Nakamura S.   +6 more
europepmc   +1 more source