Results 131 to 140 of about 2,550,027 (311)

On Amino-acids [PDF]

Biochemical Journal, 1918
openaire   +2 more sources

Amino acid requirements and amino acid supply in the sheep [PDF]

Proceedings of the Nutrition Society, 1973
D. G. Armstrong, E. F. Annison
openaire   +2 more sources

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

PCLPred: identifying plant chloride transport-related proteins using reduced amino acid alphabets and N-peptide composition

Amino Acids
Chloride transport-related proteins play critical roles in coordinating ion cycling, maintaining cellular homeostasis, and enabling plants to dynamically adapt to environmental changes, particularly under salt stress conditions.
Ge Bai, Lijia Liu, Hui Zhang, Ruimei Geng, Yong Li, Dahai Yang, Mingliang Fei, Tao Pang, Hao Wang, Aiguo Yang, He Xie, Hao Eang   +11 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Spider peptides from Brachypelma smithi with slightly different amino acids at their C-terminal loops exert different insecticidal activities

Amino Acids
The insecticidal molecules of spiders persistently evolve to ensure rapid paralysis of their prey, and the best molecules are transmitted to their progeny.
Herlinda Clement, Lilu Corrales-García, Víctor Carpanta, Galilea Jaimes, Pavel Andrei Montero-Domínguez, Elia Diego-García, Gerardo Corzo   +6 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Spermidine in Colorectal cancer: friend or foe?

Amino Acids
Colorectal cancer (CRC) is a leading cause of cancer-related mortality, and its incidence is rising among individuals, especially young, underscoring the need for novel therapeutic strategies.
Sonia Coni, Rosa Bordone, Luca Campea, Shohei Ohno, Gianluca Canettieri, Enzo Agostinelli   +5 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

A systematic review and meta-analysis of clinical trials on the effects of glutamine supplementation on gut permeability in adults

Amino Acids
The gastrointestinal tract's epithelial barrier plays a crucial role in maintaining health. This study aims to investigate the impact of glutamine supplementation on intestinal permeability, considering its importance for immune function and nutrient ...
Fatemeh Abbasi, Mohammad Mehdi Haghighat Lari, Gholamreza Reza Khosravi, Elahe Mansouri, Nastaran Payandeh, Alireza Milajerdi   +5 more
doaj   +1 more source