Results 191 to 200 of about 2,550,027 (311)

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Associations between serum amino acids and genetic liability to depression in the LURIC cohort. [PDF]

BMC Psychiatry
Krämer RM, Delgado GE, Kleber ME, Duerschmied D, März W, Moissl-Blanke AP.   +5 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Obituary: in memory of the scientific career of Professor Roger C Harris

Amino Acids
Wim Derave, Paul Greenhaff, Pat Harris, Jay Hoffman, Kent Sahlin, Craig Sale, Bryan Saunders, David Snow   +7 more
doaj   +1 more source

Vibrational Spectra, Conformations, and Optical Rotation of Aqueous Amino Acids: Zwitterions of L-Alanine and L-Valine. [PDF]

Chemphyschem
Katsyuba SA, Burganov TI, Gerasimova TP, Froitzheim T, Grimme S.   +4 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Carnitine, Amino Acids, Vitamins, and Hematological Status in Children with Classical Phenylketonuria: A Case-Control Study. [PDF]

Nutrients
Arslan S, Dişci E.
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Amino Acids-Potential Biomarkers of Histological Features for MASLD in Pediatric Obesity. [PDF]

Int J Mol Sci
Zamosteanu D, Filip N, Lozneanu L, Giusca SE, Badulescu OV, Pertea M, Filip A, Ungureanu C, Morosan E, Cojocaru E.   +9 more
europepmc   +1 more source

Amino Acid Analyzer [PDF]

Science, 1973
openaire   +2 more sources