Results 11 to 20 of about 2,101 (171)

Early matrine intervention of gut microbiota for type 2 diabetes prevention

iMetaOmics, EarlyView.
How matrine influences gut microbiota imbalance to prevent the progression of diabetes remains unclear. We conduct experiments using mice to simulate the stages of diabetes development and matrine intervention. Combined with amplicon sequencing, we find that the gut microbiota of diabetic mice continuously changes with the progression of the disease ...
Zhexue Sun, Hujie Lyu, Hailang Xu, Xianjin Qin, Wei Li   +4 more
wiley   +1 more source

Spraying drones: efficacy of integrating an avian repellent with drone hazing to elicit blackbird flock dispersal and abandonment of sunflower fields

Wildlife Biology, EarlyView.
Multiple management strategies exist to combat bird damage to agriculture. We explored combining two tools, drones as frightening devices and an avian repellent, to assess effectiveness of an integrated method to deter large flocks on complex landscapes. We evaluated the ability of a spraying drone (DJI Agras MG‐1P) deploying Avian Control (i.e. active
Jessica L. Duttenhefner, Timothy J. Greives, Page E. Klug   +2 more
wiley   +1 more source

Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling

Cell Proliferation, EarlyView.
This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava, Sidharth Bhasin, Poonam Sharma, Omkar Mahadeo Desai, Kshitiz Yadav, Ayushma, Rohan Chakraborty, Suhel Parvez, Rajesh Ramachandran, Shilpi Minocha   +9 more
wiley   +1 more source

Teleost‐specific ictacalcins exhibit similar structural organization, cation‐dependent activation, and transcriptional regulation as human S100 proteins

The FEBS Journal, EarlyView.
Calcium‐binding S100 proteins are important mediators of inflammation in humans. Distant members of this family have been recently discovered in teleost fish but their resemblance to human proteins has not been explored yet. This study demonstrates that zebrafish‐specific S100i1 and S100i2 (ictacalcins) possess identical structural organization and ...
Liz Hernández, Théo Paris, Maria Demou, Catherine Birck, Christina Begon‐Pescia, Juan Francisco Rodríguez Vidal, Sylwia D. Tyrkalska, Charlotte Bureau, Catherine Gonzalez, Juliette Gracia, Etienne Lelièvre, Victoriano Mulero, Mai Nguyen‐Chi, Laure Yatime   +13 more
wiley   +1 more source

The physiological response of juvenile diploid and triploid Arctic charr Salvelinus alpinus to exhaustive exercise

Journal of Fish Biology, EarlyView.
Abstract Triploidy is an effective tool for producing sterile fishes but often results in impaired performance in commercial aquaculture. In light of this, our study compared the physiological response to exhaustive exercise in juvenile diploid and triploid Arctic charr Salvelinus alpinus, a polar species with great potential for aquaculture.
John D. Clark, Tillmann J. Benfey
wiley   +1 more source

Rapid Clearance of Tetracapsuloides bryosalmonae Spores by Freshwater Sponge Ephydatia muelleri: Potential Implications for Controlling Proliferative Kidney Disease in Salmonids

Journal of Fish Diseases, EarlyView.
ABSTRACT Host–parasite interactions are influenced by both abiotic and biotic factors. While abiotic drivers, particularly temperature, have received considerable attention in recent years due to global climate change, the role of biotic factors remains comparatively underexplored.
Lauri Saks, Lilian Pukk, Siim Kahar, Magnus Lauringson, Anti Vasemägi   +4 more
wiley   +1 more source

A Multimodal Approach to Identify Metallothionein Metal Inducers in Nile Tilapia: Insights From Molecular Docking and Hepatocyte Exposure

Journal of Applied Toxicology, Volume 46, Issue 2, Page 590-600, February 2026.
ABSTRACT Many human activities contribute to the pollution of aquatic ecosystems, primarily through agricultural, industrial, mining, and domestic discharges into water bodies. Fish, being highly sensitive to environmental changes, serve as valuable models for monitoring the health of these ecosystems.
Jessica Zablocki da Luz, Tugstênio Lima de Souza, Aliciane de Almeida Roque, Micheli de Marchi, Roberta Pozzan, Camila Confortin, Iracema Opuskevitch, Fernando Cesar Alves da Silva Ferreira, Ciro Alberto de Oliveira Ribeiro, Francisco Filipak Neto   +9 more
wiley   +1 more source

Shorter Recruitment Periods and Higher Fecundity in High‐Latitude Populations of the Oryzias latipes Species Complex

Population Ecology, Volume 68, Issue 1, January 2026.
We report seasonal changes in gonad weight and juvenile proportion in the wild medaka populations from different latitudes. Additionally, the relationship between body size and egg number indicates a larger fecundity in high‐latitudinal populations, supporting life history adaptations in these environments with shorter reproductive seasons. ABSTRACT In
Shingo Fujimoto, Iki Murase, Hirozumi Kobayashi, Bayu K. A. Sumarto, Mitsuharu Yagi, Kazunori Yamahira   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, Volume 600, Issue 2, Page 251-266, January 2026.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins

Developmental Dynamics, Volume 255, Issue 1, Page 86-105, January 2026.
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming, Fang Liu, Hannah R. Moran, Robert L. Lalonde, Megan Adams, Nicole K. Restrepo, Parnal Joshi, Stephen C. Ekker, Karl J. Clark, Iddo Friedberg, Saulius Sumanas, Chunyue Yin, Christian Mosimann, Jeffrey J. Essner, Maura McGrail   +14 more
wiley   +1 more source