Results 21 to 30 of about 2,101 (171)

Machine Learning‐based Diagnostic Potential of Bipolar Disorder Using Gut Microbiota Signatures

open access: yesIET Systems Biology, Volume 20, Issue 1, January/December 2026.
Bipolar disorder (BD) has been linked to gut microbiota dysbiosis through the microbiota–gut–brain axis. Using 16S rRNA sequencing and machine learning, we found reduced microbial diversity, altered composition and identified 35 microbial biomarkers that enabled highly accurate BD diagnosis (AUC up to 0.95).
Hang Li   +6 more
wiley   +1 more source

Shared and Unique Patterns of Genomic Differentiation and Introgression Between Japanese Stickleback Species Across Three Sympatric Sites

open access: yesMolecular Ecology, Volume 35, Issue 2, January 2026.
ABSTRACT Hybridization and introgression frequently occur even between distantly related species. A central question in speciation research is which genomic regions act as barriers to gene flow and how genome‐wide differentiation persists despite hybridization between species.
Genta Okude   +7 more
wiley   +1 more source

Inhibitory effect of oestradiol on the cardiac KV7.1/KCNE1 channel is species dependent

open access: yesExperimental Physiology, Volume 111, Issue 1, Page 54-68, 1 January 2026.
Abstract Oestradiol (17β‐E2) is reported to prolong the cardiac action potential duration and QT interval, in part by affecting cardiac ion channels. Previous studies found inhibiting 17β‐E2 effects on the repolarizating cardiac KV7.1/KCNE1 channel, or its native current, in heterologous expression systems or tissue from animal species.
Veronika A. Linhart   +2 more
wiley   +1 more source

Mechanism of CO2 and NH3 transport through human aquaporin 1: Evidence for parallel CO2 pathways

open access: yesThe Journal of Physiology, Volume 604, Issue 1, Page 336-365, 1 January 2026.
Abstract figure legend The figure illustrates the permeation pathways for CO2, NH3 and H2O through AQP1. The panel on the left, with the wild‐type protein under control conditions, CO2 moves through monomeric pores (2 of 4 shown) but predominantly via an alternate pathway (perhaps the central pore of the tetramer).
Raif Musa‐Aziz   +4 more
wiley   +1 more source

Functional Characterisation of Microbial Communities Related to Black Stain Formation in Lascaux Cave

open access: yesEnvironmental Microbiology Reports, Volume 17, Issue 6, December 2025.
Excessive anthropization can lead to black stain alterations on cave walls. The present work reports the first metagenomic analysis of black stains threatening artwork in Lascaux Cave. Findings show new microbial taxa and genetic potential associated with black stains.
Zélia Bontemps   +3 more
wiley   +1 more source

Genetic and phenotypic comparison of natural and translocated populations of a pond‐breeding amphibian

open access: yesConservation Science and Practice, Volume 7, Issue 12, December 2025.
The translocations resulted in populations that do not differ much from natural populations in their genetic structure and fitness‐related life history traits. Abstract Translocations are a commonly used method in conservation practice and are often viewed as successful if a new population persists.
José F. Meléndez‐Cal‐y‐Mayor   +6 more
wiley   +1 more source

An Allele of Glutamate Formiminotransferase Triggers 5‐Methyl‐Tetrahydrofolate‐to‐MeFox Conversion and Facilitates Folate Biofortification in Maize

open access: yesAdvanced Science, Volume 12, Issue 42, November 13, 2025.
This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian   +15 more
wiley   +1 more source

Durable Etched Silicon Powder‐Supported Palladium Catalyst for Continuous Flow Hydrogenation and Reductive Alkylation

open access: yesChemistry–Methods, Volume 5, Issue 11, November 2025.
Etched silicon powder‐supported Pd is developed as a durable and efficient catalyst for continuous flow hydrogenation and reductive alkylation. This study develops a novel heterogeneous palladium catalyst immobilized on etched silicon powder, demonstrating high efficiency and long‐term stability under continuous flow conditions.
Zhenzhong Zhang   +4 more
wiley   +1 more source

Trans‐Synaptic Virus Tracing Reveals Reciprocal Connections of the Interpeduncular Nucleus With the Mood, Exteroceptive, Interoceptive, and Motor Control Systems

open access: yesJournal of Comparative Neurology, Volume 533, Issue 11, November 2025.
The interpeduncular nucleus (IPN) in zebrafish plays a pivotal role in directional decision‐making, social conflict, and fear responses. The anterograde and retrograde connections of the dorsal and intermediate IPN are revealed through the use of monosynaptic and trans‐synaptic viral tracers.
Audrey K. Wong   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy