Results 41 to 50 of about 4,314 (255)
Extended metal-organic solids based on benzenepolycarboxylic and aminobenzoic acids [PDF]
This article describes the recent results obtained in our laboratory on the interaction of polyfunctional ligands with divalent alkaline earth metal ions and a few divalent transition metal ions.
Anantharaman, G.+4 more
core +2 more sources
Innovative Multipodal Ligands Derived from Tröger's Bases for the Sensitization of Lanthanide(III) Luminescence [PDF]
Herein, the synthesis and characterization of the first family of multipodal ligands with a Tröger's base framework designed for the preparation of luminescent lanthanide(III) complexes are reported.
Barja, Beatriz Carmen+6 more
core +2 more sources
Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues [PDF]
The ability to effectively detect bacterial infection in human tissues is important for the timely treatment of the infection. However, traditional techniques fail to visualize bacterial species adhered to host cells in situ in a target-specific manner ...
Chen, Zhao Hong+13 more
core +1 more source
ABSTRACT The ornamental fish trade has facilitated the global dissemination of parasites, posing significant biosecurity risks. This study documents the first detection of the nematode Philometroides sanguineus in farmed goldfish (Carassius auratus) in Emilia‐Romagna, Italy.
Teresa Pirollo+6 more
wiley +1 more source
Percutaneous Delivery of Thalidomide and Its N-Alkyl Analogs [PDF]
Purpose . The purpose of this study was to determine the permeation parameters of thalidomide and three of its N -alkyl analogs and to establish a correlation between the physicochemical properties of these compounds and their percutaneous rates of ...
du Plessis, Jeanetta+4 more
core +1 more source
ABSTRACT Although population genomics approaches have been successful in identifying regions of the genome shaped by natural selection, progress in dissecting the molecular mechanisms of adaptive variants and traits has been slow. By integrating multi‐tissue (gill, spleen, olfactory rosette, whole eye, and liver) transcriptomes from 16 wild Eurasian ...
M. Yu. Ozerov+4 more
wiley +1 more source
Inhibitory effect of oestradiol on the cardiac KV7.1/KCNE1 channel is species dependent
Abstract Oestradiol (17β‐E2) is reported to prolong the cardiac action potential duration and QT interval, in part by affecting cardiac ion channels. Previous studies found inhibiting 17β‐E2 effects on the repolarizating cardiac KV7.1/KCNE1 channel, or its native current, in heterologous expression systems or tissue from animal species.
Veronika A. Linhart+2 more
wiley +1 more source
Homeosteric analogues of folic acid, 8-oxadihydropteridines [PDF]
The introduction of heteroartoms in the pyrazine portion of the pteridine ring has produced compounds which display antifolate activity. The initial objective of this research program was to develop a convenient synthesis of the 8-oxadihydropteridine ...
Dunn, Danny LeRoy
core
New Pyridobenothiazolone Derivatives Display Nanomolar Pan‐Serotype Anti‐Dengue Virus Activity
A ligand‐based strategy is employed, starting from hit compound 2, to develop the C‐2 modified pyridobenzothiazolone 19 as a pan‐serotype nanomolar DENV‐1‐4 inhibitor. Investigations of the mechanism reveal the peculiar ability to abolish the infectivity of virions in a second infection.
Tommaso Felicetti+13 more
wiley +1 more source
Physicochemical Characterization and Solubility Analysis of Thalidomide and Its N-Alkyl Analogs [PDF]
Purpose . The present study was primarily aimed at exploring the feasibility of improving percutaneous delivery via chemical manipulation of the thalidomide molecule to form analogs with improved physicochemical properties.
Flynn, Gordon L.+4 more
core +1 more source