Results 51 to 60 of about 4,314 (255)

Para-Aminobenzoic Acid in Human Leukaemias [PDF]

Nature, 1949
BICHEL1, and later Zarafonetis and co-workers2, recorded interesting data concerning the effect of para-aminobenzoic acid in leukaemias.
M. Tényi, E. Keleman
openaire   +3 more sources

Rescue of loss‐of‐function long QT syndrome‐associated mutations in KV7.1/KCNE1 by the endocannabinoid N‐arachidonoyl‐L‐serine (ARA‐S)

British Journal of Pharmacology, Volume 182, Issue 13, Page 2861-2877, July 2025.
Abstract Background and Purpose Congenital long QT syndrome (LQTS) involves genetic mutations affecting ion channels, leading to a prolonged QT interval and increased risk of potentially lethal ventricular arrhythmias. Mutations in the genes encoding KV7.1/KCNE1 are the most frequent, with channel loss‐of‐function contributing to LQTS.
Irene Hiniesto‐Iñigo, Akshay Sridhar, Julien Louradour, Alicia De la Cruz, Siri Lundholm, Amaia Jauregi‐Miguel, Federica Giannetti, Luca Sala, Katja E. Odening, H. Peter Larsson, Nina E. Ottosson, Sara I. Liin   +11 more
wiley   +1 more source

Effect of Three Heating Guns on the Temperature of Two Bulk‐Fill Resin‐Based Composites

Journal of Esthetic and Restorative Dentistry, Volume 37, Issue 7, Page 1802-1813, July 2025.
ABSTRACT Objective To evaluate the effect of three heating guns—Phasor (Vista Apex, Racine, USA), VisCalor (VOCO, Cuxhaven, Germany), and Compex HD (AdDent Inc. Danbury, USA)—on the temperature changes of two bulk‐fill resin‐based composites (RBCs): VisCalor Bulk (VBF, VOCO) and Filtek One Bulk Fill Restorative (OBF, Solventum, St.
Juliana Anany Gonzales Guarneri, Cristiane Maucoski, Fabrício Mezzomo Collares, Richard Bengt Price, Cesar Augusto Galvão Arrais   +4 more
wiley   +1 more source

Influência da forma farmacêutica (emulsão múltipla A/O/A, emulsão O/A e pomada) sobre a permeação e retenção cutânea da paromomicina [PDF]

, 2004
Pomadas contendo paromomicina (PA) são utilizadas no tratamento tópico da leishmaniose cutânea. Embora a influência do veículo seja crucial para otimização de formulações contendo PA, este aspecto não tem sido investigado experimentalmente. Neste estudo,
Ferreira, Lucas Antônio Miranda, Gomes, Sérgio Fernandes de Oliveira, Nunan, Elzíria de Aguiar   +2 more
core   +4 more sources

First Phosphonic‐Type Inhibitors and Activity‐Based Probes Specific to the O'nyong‐nyong Virus Capsid Protease

ChemMedChem, Volume 20, Issue 12, June 17, 2025.
The serine capsid protease (CP) catalyzes a crucial process of the alphaviral replication cycle; therefore, it constitutes an interesting therapy target. Herein, the O'nyong‐nyong virus CP profile activity with a specific fluorogenic substrate is analyzed and examines the inhibitory activity of a new series of phosphonic analogs of tryptophan and ...
Karolina Torzyk‐Jurowska, Agnieszka Łupicka‐Słowik, Renata Grzywa, Yuliya Chykunova, Krzysztof Pyrć, Marcin Sieńczyk   +5 more
wiley   +1 more source

Improved Chemical Synthesis of Avenanthramides Family and its Analogs by Mixed Anhydride Method

European Journal of Organic Chemistry, Volume 28, Issue 21, June 3, 2025.
Valuable phytochemicals, including avenanthramides A, B, C, E, and some analogs, have been rapidly prepared as carbonate‐protected derivatives in acetone, achieving high yields by crystallization.. This process utilizes the mixed anhydride method with a triethylamine‐isobutyl chloroformate reagent system. The protection can be readily removed on demand
Armando Zarrelli, Luigi Longobardo
wiley   +1 more source

Design and In Vitro Biological Evaluation of a Novel Organotin(IV) Complex with 1-(4-Carboxyphenyl)-3-ethyl-3-methylpyrrolidine-2,5-dione [PDF]

, 2019
A novel triphenyltin(IV) compound with 1-(4-carboxyphenyl)-3-ethyl-3-methylpyrrolidine-2,5-dione was synthesized and characterized by IR, NMR spectroscopy, mass spectrometry, and elemental analysis.
Banjac, Nebojša, Božić, Bojan D., Kaludjerović, Goran N., Pantelić, Nebojša, Stanojković, Tatjana P., Zizak, Zeljko, Zmejkovski, Bojana B.   +6 more
core   +4 more sources

Confinement by Liquid‐Liquid Interface Replicates In Vivo Neutrophil Deformations and Elicits Bleb‐Based Migration

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Leukocytes sense mechanical cues provided by surrounding cells to regulate motility. Replicating the confining pressures applied by soft, elastic tissues in vitro is challenging. Here, the use of liquid‐liquid interfaces is introduced to model forces exerted by surrounding cells. Confining pressures are tunable by controlling interfacial curvature, and
Jonathan H. Schrope, Adam Horn, Kaitlyn Lazorchak, Clyde W. Tinnen, Jack J Stevens, Mehtab Farooqui, Tanner Robertson, Jiayi Li, David Bennin, Terry Juang, Adeel Ahmed, Chao Li, Anna Huttenlocher, David J Beebe   +13 more
wiley   +1 more source

Peyronie's disease - a perspective on the disease and the long-term results of radiotherapy [PDF]

, 2017
From 1966 to 1988, 98 of 108 patients with symptomatic Peyronie's disease received radiotherapy at our institution. In 11 of 61 patients (18%) who attended the clinic regularly for follow-up for longer than a year, new lesions distinct from the original ...
Doman, M. J., Goedhals, L., Viljoen, I. M.   +2 more
core   +1 more source

Synthesis and structural characterization of Dinuclear Cerium(III) and Erbium(III) complexes of Nicotinic acid or 2-Aminobenzoic acid [PDF]

, 2018
A cerium(III) complex, [Ce2(NA)6(H2O)4] (1) and anerbium(III) complex, [Er2(2- AMB)6(H2O)4]∙3H2O (2), where NA = nicotinic acid and 2-AMB =2-aminobenzoic acid, have been prepared and characterized by IR spectroscopy, thermogravimetric analysis and X-ray ...
Islam Ullah Ullah Khan (7162889), Mark Elsegood (1249893), Muhammad Nawaz Tahir (536376), Nadia Jabeen (7162892), Sadaf Mutahir (7162895), Saeed Ahmad (704441), Sajjad Hussain (41458)   +6 more
core   +1 more source