Cocrystallization is a technique to optimize solid forms that shows great potential to improve the solubility of active pharmaceutical ingredients (APIs).
Zi Li, A. Matzger
semanticscholar +1 more source
Coenzyme Q10 deficiencies: pathways in yeast and humans. [PDF]
Coenzyme Q (ubiquinone or CoQ) is an essential lipid that plays a role in mitochondrial respiratory electron transport and serves as an important antioxidant.
Awad, Agape M+5 more
core
Inflammation, DNA-centered radicals, and oxidative genotoxicity: The role of HOCl produced by myeloperoxidase in carcinogenesis [PDF]
Myeloid cells (macrophages and neutrophils) infiltrate and synthesize myeloperoxidase (MPO) in sites of inflammation, producing gentotoxicity. In RAW 264.7 macrophages, bacterial lipopolysaccharide (LPS) induces superoxide radical anion, nuclear ...
Dario C. Ramirez+2 more
core +2 more sources
A novel approach is developed to pancreatic cancer screening by targeting the cyclophili‐B (CypB)protein using a molecularly imprinted polymer with the electrode material containing Pt single‐atom‐doped/SeS2‐Ti3CNTx MXene. The quantification of CypB in pancreatic cancer tissues provide an insight into the association of CypB with pancreatic cancer ...
Sathish Panneer Selvam+3 more
wiley +1 more source
NEXAFS and XPS of p-Aminobenzoic Acid Polymorphs: The Influence of Local Environment [PDF]
Nitrogen K-edge XPS and NEXAFS of the two polymorphic forms of para- aminobenzoic acid (PABA) are significantly different reflecting variation in hydrogen bonding. Alteration in hydrogen bonding at the amino group leads to a shift to high energy for both
A Gainar+6 more
core +1 more source
How Activated Carboxylic Acids Can Drive Dissipative Systems
This concept aims to describe the dissipative chemical systems driven by activated carboxylic acids (ACAs), identifying three different types: systems under dissipative conditions (Type 1), energy ratchets (Type 2), and non‐equilibrium steady states (NESS) systems (Type 3).
Matteo Valentini+2 more
wiley +1 more source
Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate. [PDF]
BACKGROUND: Safe, cheap and effective adjunct therapies preventing the development of, or reducing the mortality from, severe malaria could have considerable and rapid public health impact.
Alexander, Neal D+16 more
core +5 more sources
Examining mixotrophic fermentation in fed‐batch mode for C1‐gas valorization
Abstract BACKGROUND C1‐gases like CO and CO2, significant contributors to climate change, offer the potential for sustainable bioconversion into valuable products. The study explored mixotrophic fermentation using C1‐gases in fed‐batch mode to improve the production of target compounds, focusing on Clostridium aceticum and Clostridium carboxidivorans ...
Marina Fernández‐Delgado+5 more
wiley +1 more source
3-Aminobenzoic acid–1,2-bis(4-pyridyl)ethane (1/1)
The asymmetric unit of the title compound, C12H12N2·C7H7NO2, contains two 3-aminobenzoic acid molecules and two 1,2-bis(4-pyridyl)ethane molecules.
Fwu Ming Shen, Shie Fu Lush
doaj +1 more source
Rational Design of Pore Size and Functionality in a Series of Isoreticular Zwitterionic Metal-Organic Frameworks [PDF]
The isoreticular expansion and functionalization of charged-polarized porosity has been systematically explored by the rational design of 11 isostructural zwitterionic metal-organic frameworks (ZW-MOFs).
Aulakh, D+8 more
core +13 more sources