Results 41 to 50 of about 3,922 (162)

Abunmix enables the simple and robust multiplexed immunofluorescence imaging

open access: yesVIEW, Volume 7, Issue 3, June 2026.
Multiplexed fluorescence imaging is limited by bleed‐through signals arising from the use of antibodies derived from the same host species. Abunmix can separate signals from multiple antibodies generated from the same host species using a signal unmixing algorithm.
Woonggi La   +14 more
wiley   +1 more source

Bacterial Biosensors for in Vivo Spatiotemporal Mapping of Root Secretion1[CC-BY]

open access: yesPlant Physiology, 2017
Development of a suite of rhizobial lux reporters to map in vivo root exudation, spatially and temporally. Plants engineer the rhizosphere to their advantage by secreting various nutrients and secondary metabolites.
F. Pini   +10 more
semanticscholar   +1 more source

Intrapopulation Metabolic Variation Reflects Growth Differences: A Cross‐Sectional Study on Gammarides

open access: yesEcology and Evolution, Volume 16, Issue 5, May 2026.
For the first time in Gammarus insensibilis, a single‐organism 1H NMR metabolomics approach was applied to investigate the intrapopulation variability in growth trajectories showing how divergent size classes, despite being of the same age, reflect alternative resource‐allocation strategies.
Federica De Castro   +5 more
wiley   +1 more source

Blood‐Based Epigenetic Signatures in Brazilian Males With Alcohol Use Disorder

open access: yesAddiction Biology, Volume 31, Issue 5, May 2026.
This study represents the first epigenome‐wide association analysis of Alcohol Use Disorder (AUD) in a genetically and culturally diverse Brazilian cohort. Genome‐wide DNA methylation profiling revealed hypomethylation in genes and pathways related to neuronal development, synaptic organization, intracellular signaling and cellular stress responses in ...
Laís da Silva Pereira‐Rufino   +15 more
wiley   +1 more source

Growth, Photosynthesis and Root Metabolome Responses to Graded Hypoxia in Contrasting Rice Cultivars

open access: yesJournal of Agronomy and Crop Science, Volume 212, Issue 3, May 2026.
ABSTRACT Rice is an economically important crop and a staple food for a large proportion of the world's population. Although rice is generally adapted to flooded soils, cultivars may differ in their responses to reduced oxygen availability. Here, we evaluated growth, physiological performance and organ‐specific metabolic profiles of two rice cultivars ...
Jesimiel da Silva Viana   +5 more
wiley   +1 more source

Transaminase and Norcoclaurine Synthase One‐Pot Cascades Towards (1S)‐Tetrahydroisoquinolines

open access: yesChemBioChem, Volume 27, Issue 6, 27 March 2026.
A TAm‐NCS cascade towards THIQs has been established, starting from amines with the in situ production of aldehydes. The cascade was used with a variety of nonfunctionalized and functionalized amines, and reaction conditions modified to enhance formation of the desired cross‐products.
Jianxiong Zhao   +5 more
wiley   +1 more source

Design of Next Generation Polymyxins with Lower Toxicity: The Discovery of SPR206

open access: yesACS Infectious Diseases, 2019
Polymyxins are an important class of antibiotics for the treatment of bacterial infections due to multi-drug resistant Gram-negative pathogens. However, their clinical utility is limited by nephrotoxicity.
P. Brown   +13 more
semanticscholar   +1 more source

Biosynthesis of the Stress-Protectant and Chemical Chaperon Ectoine: Biochemistry of the Transaminase EctB

open access: yesFrontiers in Microbiology, 2019
Bacteria frequently adapt to high osmolarity surroundings through the accumulation of compatible solutes. Ectoine is a prominent member of these types of stress protectants and is produced via an evolutionarily conserved biosynthetic pathway beginning ...
A. Richter   +8 more
semanticscholar   +1 more source

Enhanced production of gamma-aminobutyrate (GABA) in recombinant Corynebacterium glutamicum by expressing glutamate decarboxylase active in expanded pH range

open access: yesMicrobial Cell Factories, 2015
BackgroundGamma-aminobutylate (GABA) is an important chemical in pharmacetucal field and chemical industry. GABA has mostly been produced in lactic acid bacteria by adding L-glutamate to the culture medium since L-glutamate can be converted into GABA by ...
Jae Woong Choi   +5 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy