Results 11 to 20 of about 374 (149)
Production of nonnatural straight-chain amino acid 6-aminocaproate via an artificial iterative carbon-chain-extension cycle [PDF]
bioRxiv, 2019 Bioplastics produced from microbial source are promising green alternatives to traditional petrochemical-derived plastics. Nonnatural straight-chain amino acids, especially 5-aminovalerate, 6-aminocaproate and 7-aminoheptanoate are potential monomers for
Michael P. Torrens-Spence +1 more
semanticscholar +4 more sources
L-Lysine α-Oxidase: Enzyme with Anticancer Properties
Pharmaceuticals, 2021 L-lysine α-oxidase (LO), one of L-amino acid oxidases, deaminates L-lysine with the yield of H2O2, ammonia, and α-keto-ε-aminocaproate. Multiple in vitro and in vivo studies have reported cytotoxic, antitumor, antimetastatic, and antitumor activity of LO.
E. V. Lukasheva +4 more
semanticscholar +1 more source
Cyclic 68Ga-Labeled Peptides for Specific Detection of Human Angiotensin-Converting Enzyme 2
Journal of Nuclear Medicine, 2021 Visual Abstract In this study, we developed angiotensin-converting enzyme 2 (ACE2)–specific, peptide-derived 68Ga-labeled radiotracers, motivated by the hypotheses that ACE2 is an important determinant of severe acute respiratory syndrome coronavirus 2 ...
Matthew F. L. Parker +5 more
semanticscholar +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 Bioproduction of 5-aminovalerate (5AVA) from renewable feedstock can support a sustainable biorefinery process to produce bioplastics, such as nylon 5 and nylon 56.
Jie Cheng +6 more
semanticscholar +1 more source
Structural basis of strict substrate recognition of l‐lysine α‐oxidase from Trichoderma viride
Protein Science, 2020 l‐Lysine oxidase (LysOX) is a FAD‐dependent homodimeric enzyme that catalyzes the oxidative deamination of l‐lysine to produce α‐keto‐ε‐aminocaproate with ammonia and hydrogen peroxide.
H. Kondo +9 more
semanticscholar +1 more source
Weaving the fabric of science: Dynamic network models of science's unfolding structure [PDF]
, 2015 Science is a complex system. Building on Latour's actor network theory, we model published science as a dynamic hypergraph and explore how this fabric provides a substrate for future scientific discovery. Using millions of abstracts from MEDLINE, we show
Evans, James A. +2 more
core +1 more source
Cyclic gallium-68 labeled peptides for specific detection of human angiotensin-converting enzyme 2
bioRxiv, 2020 In this study, we developed ACE2-specific, peptide-derived 68Ga-labeled radiotracers, motivated by the hypotheses that (1) ACE2 is an important determinant of SARS-CoV-2 susceptibility, and (2) that modulation of ACE2 in COVID-19 drives severe organ ...
Matthew F. L. Parker +5 more
semanticscholar +1 more source
The Journal of Pathology, Volume 229, Issue 3, Page 390-399, February 2013., 2013 Abstract A subgroup of HER2‐overexpressing breast tumours co‐expresses p95$^{{\rm{HER2}}}$, a truncated HER2 receptor that retains a functional HER2 kinase domain but lacks the extracellular domain, thus impairing trastuzumab binding. We evaluated p95$^{{\rm{HER2}}}$ expression in 99 frozen breast carcinoma samples by western blot analysis.
Daniele Recupero +12 more
wiley +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2013, Issue 1, 2013., 2013 Oat, a rich source of soluble fiber, was considered to have a possible preventive effect on the progression of diabetic nephropathy. The present study aimed to assess this preventive activity in a rat model of diabetic nephropathy. Adult Wister rats were injected by streptozotocin (65 mg/kg).
Abdulrahman L. Al-Malki +1 more
wiley +1 more source