Results 11 to 20 of about 374 (134)

Spontaneous and pronase‐induced HER2 truncation increases the trastuzumab binding capacity of breast cancer tissues and cell lines

The Journal of Pathology, Volume 229, Issue 3, Page 390-399, February 2013., 2013
Abstract A subgroup of HER2‐overexpressing breast tumours co‐expresses p95$^{{\rm{HER2}}}$, a truncated HER2 receptor that retains a functional HER2 kinase domain but lacks the extracellular domain, thus impairing trastuzumab binding. We evaluated p95$^{{\rm{HER2}}}$ expression in 99 frozen breast carcinoma samples by western blot analysis.
Daniele Recupero, Lorenzo Daniele, Caterina Marchiò, Luca Molinaro, Isabella Castellano, Paola Cassoni, Alberto Righi, Filippo Montemurro, Piero Sismondi, Nicoletta Biglia, Giuseppe Viale, Mauro Risio, Anna Sapino   +12 more
wiley   +1 more source

Oat Protects against Diabetic Nephropathy in Rats via Attenuating Advanced Glycation End Products and Nuclear Factor Kappa B

Evidence-Based Complementary and Alternative Medicine, Volume 2013, Issue 1, 2013., 2013
Oat, a rich source of soluble fiber, was considered to have a possible preventive effect on the progression of diabetic nephropathy. The present study aimed to assess this preventive activity in a rat model of diabetic nephropathy. Adult Wister rats were injected by streptozotocin (65 mg/kg).
Abdulrahman L. Al-Malki, Ravirajsinh Jadeja   +1 more
wiley   +1 more source

The heterogeneity of combining sites of anti-benzylpenicilloyl antibodies obtained from individual rabbits: changes in combining sites of gammaG and gammaM antibodies during the immune response.

Journal of Immunology, 1968
Nine rabbits were immunized with benzylpenicilloyl-human γG conjugate (BPO-HGG). Radioiodinated γG and γM were prepared from the anti-BPO-HGG sera of individual rabbits collected 10 days and 10 weeks after the first immunization.
T. Atsumi, M. Adachi, Y. Kinoshita, M. Kawasaki, Y. Horiuchi   +4 more
semanticscholar   +1 more source

The binding reactions of antibodies specific for the 2,6-dinitrophenyl group.

Journal of Immunology, 1969
Rabbit and guinea pig antibodies specific for the 2,6-DNP group were isolated from sera by specific precipitation and hapten elution. Anti-2,6-DNP-antibodies formed late in the immune response displayed greater cross-reactivity with 2,4-DNP and 2,4,6 ...
J. R. Little, Wayne A. Border, Ralph B. Freidin   +2 more
semanticscholar   +1 more source

Mechanistic Analysis of Stereodivergent Nitroalkane Cyclopropanation Catalyzed by Nonheme Iron Enzymes. [PDF]

J Am Chem Soc, 2023
Ushimaru R, Cha L, Shimo S, Li X, Paris JC, Mori T, Miyamoto K, Coffer L, Uchiyama M, Guo Y, Chang WC, Abe I.   +11 more
europepmc   +1 more source

Tranexamic versus aminocaproic acids in patients with total hip arthroplasty: a retrospective study. [PDF]

BMC Musculoskelet Disord, 2022
Xie H, Yang YS, Tian SM, Wang BJ, Fu WM, Cheng LL, Jiang NN, Gu G, Zhao DW.   +8 more
europepmc   +1 more source

Surprising combinations of research contents and contexts are related to impact and emerge with scientific outsiders from distant disciplines. [PDF]

Nat Commun, 2023
Shi F, Evans J.
europepmc   +1 more source

Cerium-Containing N-Acetyl-6-Aminohexanoic Acid Formulation Accelerates Wound Reparation in Diabetic Animals. [PDF]

Biomolecules, 2021
Blinova E, Pakhomov D, Shimanovsky D, Kilmyashkina M, Mazov Y, Demura T, Drozdov V, Blinov D, Deryabina O, Samishina E, Butenko A, Skachilova S, Sokolov A, Vasilkina O, Alkhatatneh BA, Vavilova O, Sukhov A, Shmatok D, Sorokvasha I, Tumutolova O, Lobanova E.   +20 more
europepmc   +1 more source

THE MOTOR END-PLATE REACTION WITH NAPHTHOL-AS ε-AMINOCAPROATE [PDF]

, 1964
Väinö K. Hopsu, J. PONTINEN
openalex   +1 more source

Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage. [PDF]

Cochrane Database Syst Rev, 2022
Germans MR, Dronkers WJ, Baharoglu MI, Post R, Verbaan D, Rinkel GJ, Roos YB.   +6 more
europepmc   +1 more source