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Crystallization and 1.6 Å resolution crystal structure of an acylated GLP-1/GIP analogue peptide. [PDF]
Acta Crystallogr F Struct Biol CommunMitchell HM +3 more
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Metabolic Profiling Analysis of Cytochrome B5 Production in E. Coli N4830-1 Using GC-MS
Tengsuttiwat T +5 more
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Transport of ?-aminoisobutyric acid in mammalian pancreatic �-cells
Diabetologia, 1971Transport of α-aminoisobutyric acid (AIB) was studied in microdissected pancreatic islets of obesehyperglycaemic mice. These islets are characterized by an unusually high proportion of insulin-secretingβ-cells. The following main observations were made. 1. The islet cells exhibited a concentrative uptake of AIB, yielding distribution ratios much higher
B Hellman, J Sehlin, I B Täljedal
exaly +3 more sources
β-Aminoisobutyric acid as a marker of thymine catabolism in malignancy
Clinica Chimica Acta, 1987Urine from untreated patients with various tumours and controls has been examined for the excretion of beta-aminoisobutyric acid and uric acid. The patients were classified into four groups: I, beta-aminoisobutyric acid and uric acid both normal; II, beta-aminoisobutyric acid normal, uric acid elevated; III, beta-aminoisobutyric acid elevated, uric ...
Albert H Van Gennip +2 more
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NAP Alpha-Aminoisobutyric Acid (IsoNAP)
Journal of Molecular Neuroscience, 2013We set out to identify NAP (davunetide) analogs, providing neuroprotection and reducing tau pathology, specifically addressing protection against protein misfolding. NAP (NAPVSIPQ, intranasal formulation AL-108) is a drug candidate that (1) had a statistically significant impact on two measures, namely digit span and delayed-match-to-sample, tests of ...
Illana, Gozes +4 more
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The effect of endotoxin on plasma α-aminoisobutyric acid
Experientia, 1980The i.v. injection of bacterial endotoxin into dogs was found to cause a rapid increase in plasma levels of infused alpha-aminoisobutyric acid. The findings suggest that nonmetabolic factors (tissue uptake, fluid shifts) influence amino acid distribution during endotoxemia.
R E, Kuttner, J J, Spitzer
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Some metabolic studies of β-aminoisobutyric acid
Life Sciences, 1967Abstract DL-β-aminoisobutyric acid-β- 14 C was synthesized and administered intraperitoneally to rats. Radioactivity was incorporated into all vascular tissues. Maximum radioactivity was found in rat livers and kidneys within 30 minutes after injection. β-Aminoisobutyric acid-β- 14 C was readily converted to 14 CO 2 .
I K, Mushahwar, A, Alter, A R, Schulz
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Identification of β-aminoisobutyric acid in uremic serum
Clinica Chimica Acta, 1976An unidentified ninhydrin-positive substance found in uremic sera but not found in normal sera was isolated by gel-filtration through Sephadex G-75 followed by high voltage paper electrophoresis (pH 3.5), and identified as beta-aminoisobutyric acid using paper chromatography and automated amino acid analyzer.
F, Gejyo, Y, Kinoshita, T, Ikenaka
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The title acid, 3-amino-2-methylpropanoic acid monohydrate, C4H9NO2.H2O, crystallized in the centrosymmetric space group Pbca in the zwitterionic form. The three H atoms on N, which are involved in hydrogen bonding, are ordered. The three intermolecular N-H...O hydrogen bonds have N...O distances ranging from 2.758 (2) to 2.809 (2) A and N-H...O angles
A J, Dobson, R E, Gerkin
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