Results 121 to 130 of about 8,541,382 (232)

Hepatic 5-aminolevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins

, 2008
Hepatic 5-aminolevulinic acid synthase, the first and normally rate-controlling enzyme of heme biosynthesis, is regulated by heme. One of the known mechanisms whereby increased cellular heme regulates 5-aminolevulinic acid synthase is by decreasing the ...
Pepe, Joyce A., Lambrecht, Richard W., Cable, Edward Earl, Bonkovsky, Herbert L., Gildemeister, Otto S., Donohue, Susan E.   +5 more
core   +1 more source

From Deficiency to Therapy: Systemic Consequences of ALAS1 Disruption and the Protective Role of 5-ALA

Life
Heme, an essential prosthetic group involved in mitochondrial respiration and transcriptional regulation, is synthesized via the rate-limiting enzyme 5-aminolevulinic acid synthase (ALAS).
Koen van Wijk, Osamu Nakajima
doaj   +1 more source

5-aminolevulinic acid-incorporated nanoparticles of methoxy poly(ethylene glycol)-chitosan copolymer for photodynamic therapy

, 2013
Chung-Wook Chung,1,* Kyu-Don Chung,2,* Young-Il Jeong,1 Dae Hwan Kang,1 1National Research and Development Center for Hepatobiliary Disease, Pusan National University Yangsan Hospital, Gyeongnam, Republic of Korea; 2Department of Anesthesiology and Pain ...
Chung CW, Jeong YI, Kang DH, Chung KD
core  

Influence of 5-Aminolevulinic Acid and Red Light on Collagen Metabolism of Human Dermal Fibroblasts

, 2003
Patients with localized scleroderma receiving topical photodynamic therapy with 5-aminolevulinic acid show a reduction in skin tightness, suggesting that this therapy reduces skin sclerosis.
Landthaler, Michael, Karrer, Sigrid, Weiderer, Petra, Szeimies, Rolf-Markus, Bosserhoff, Anja Kathrin   +4 more
core   +1 more source

Comparative Effectiveness of 5-Aminolevulinic Acid Photodynamic Therapy

Comparative Effectiveness of 5-Aminolevulinic Acid Photodynamic Therapy with No Incubation Versus One-Hour Incubation for the Treatment of Actinic Keratosis: A Randomized-Controlled ...
Alam, M
core   +1 more source

La porfiria aguda intermitente y el cirujano: un reto diagnóstico Reporte de un caso y revisión de la literatura Acute intermittent porphyria and the surgeon: a diagnostic challenge. Case report and literature review

Revista Colombiana de Cirugía, 2011
La porfiria intermitente aguda es conocida, en el ámbito de la cirugía, como una de las causas de abdomen agudo no quirúrgico. No obstante, lo que no se menciona con frecuencia es la posibilidad de que cualquier procedimiento quirúrgico precipite un ...
Lilian Torregrosa, Juan Carlos Ayala, Sergio Cervera, Carlos Andrés Villa   +3 more
doaj  

Novel concepts of light application for ALA-PDT of malignant gliomas [PDF]

, 2010
Beck, Tobias
core   +1 more source

5-Aminolevulinic acid-mediated protoporphyrin IX accumulation in the tumor microenvironment of glioma and its implications for 5-aminolevulinic acid-based local tumor therapies: A review of the literature. [PDF]

Neuro Oncol
Özdemir Z, Gallus M, Müther M, Stummer W.   +3 more
europepmc   +1 more source

Radiodynamic Therapy Using Local Administration of 5-Aminolevulinic Acid for <i>In Vivo</i> Osteosarcoma Xenograft Model. [PDF]

In Vivo
Tanemura Y, Nakamura T, Matsuyama Y, Hagi T, Date H, Iino T, Hasegawa M.   +6 more
europepmc   +1 more source

Novel bioconjugates of aminolevulinic acid with vitamins

, 2008
5-Aminolevulinic acid (ALA) and derivs. thereof have been successfully used in photodynamic cancer therapy (PDT). The synthesis of novel bioconjugates combining ALA with two lipophilic and one hydrophilic vitamins is reported. The new bioconjugates allow
Neier, Reinhard, Weber, Joanne, Vallinayagam, Ramakrishnan   +2 more
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