Results 91 to 100 of about 2,267 (195)

Asymmetric Organocatalyzed Synthesis of α‐Aminophosphinates via Thiourea Anion‐Binding Catalysis

European Journal of Organic Chemistry, Volume 27, Issue 11, March 18, 2024.
P‐Stereogenic α‐aminophosphinates were obtained in high enantioselectivity via anion‐binding catalysis with thiourea catalysts, further expanding the range of nucleophiles that can be used in this type of catalysis. Abstract Thioureas catalyze the reaction of phosphonites with in situ‐generated isoquinolinium salts to give C and P‐stereogenic α ...
Cáoimhe J. Niland, Joseph J. Ruddy, Martin P. O'Fearraigh, Eoghan M. McGarrigle   +3 more
wiley   +1 more source

Biological Activity of Late Transition Metal‐Based Compounds: From Computational and Theoretical Studies to Laboratory Exploration and Beyond

Bioinorganic Chemistry and Applications, Volume 2024, Issue 1, 2024.
The use of metal compounds such as cisplatin and its derivatives as therapeutic and diagnostic agents against various diseases is well established. Although metallodrugs have been very successful clinically, low therapeutic selectivity and the potential toxicity of the metal compounds mandate the need for a continuous search for more efficient and ...
Ngonidzashe Ruwizhi, Thishana Singh, Bernard O. Omondi, Muhammad D. Bala, Anastasios Keramidas   +4 more
wiley   +1 more source

New α-Aminophosphonates as Corrosion Inhibitors for Oil and Gas Pipelines Protection [PDF]

, 2019
The problem of corrosion of metal equipment is one of the most actual problems in oil industry. One of the methods to solve this problem is the development of new low-toxic, accessible and effective corrosion inhibitors.
Kazimova, Kamila, Nikitin, Evgeny, Shumatbaev, Georgy, Sinyashin, Kirill, Terenzhev, Dmitriy   +4 more
core   +1 more source

One-Pot Synthesis and Antimicrobial Activity of Novel α-Aminophosphonates Using TMG

E-Journal of Chemistry, 2011
α-Aminophosphonates (4a-j) were synthesized in one-pot simultaneous reaction of 4-bromo-3-methyl benzenamine (1), dimethylphosphite (3) and different aromatic aldehydes (2a-j) by Kabachnik-Fields reaction in the presence of tetramethylguanidine (TMG) (10
B. Siva Kumar, Y. Haranadha Reddy, C. Radha Rani, G. Chnadra Sekhar Reddy   +3 more
doaj   +1 more source

Enantioselective α-Aminophosphonate Functionalization of Indole Ring through an Organocatalyzed Friedel-Crafts Reaction [PDF]

, 2018
Chiral phosphoric acids efficiently catalyze the asymmetric Friedel−Crafts reaction of several indoles with α-iminophosphonates to afford enantioenriched hybrid α-aminophosphonate functionalized indole derivatives.Financial support from the Ministerio
Maestro Burzaco, Aitor, Martínez de Marigorta Izaga, Edorta, Palacios Gambra, Francisco Javier, Vicario Hernando, Javier   +3 more
core   +2 more sources

Synthesis of Two Novel Homologous Polyphosphoesters Containing Aminophosphonate Units and Cytotoxicity of Some Low-Molecular and Polymeric Aminophosphonate Derivatives

Advances in Materials Science and Engineering, 2018
Two novel polyphosphoesters containing anthracene- and furan-derived aminophosphonate moieties, namely, poly[oxyethylene(aminophosphonate-co-H-phosphonate)]s P-12 and P-13, were synthesized through an addition of poly(oxyethylene H-phosphonate) to 9 ...
Ivanka Kraicheva, Georgi Momekov, Rositsa Mihaylova, Margarita Topashka-Ancheva, Ivelina Tsacheva, Ivanka Stoineva, Elitsa Vodenicharova, Paraskev Nedialkov   +7 more
doaj   +1 more source

Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitors [PDF]

, 2014
Plasmodium parasites, the causative agents of malaria, have developed resistance to most of our current antimalarial therapies, including artemisinin combination therapies which are widely described as our last line of defense. Antimalarial agents with a
Abdel-Magid A. F., Adams P. D., Afonine P. V., Alessandro Paiardini, Androulakis S., Babine R. E., Battye T. G., Biffis A., Bramucci E., Brunger A. T., Carroll R. K., CCP4., Changklungmoa N., Chiara Ruggeri, Chouhan G., Chowdhury N., Correa A., Cristau H. J., Deprez-Poulain R., Didier E. S., Dong L., Duffy S., Eswar N., Evans P., Evans P. R., Flipo M., Flipo M., Flipo M., Freedman L. D., Harbut M. B., Hitzerd S. M., Huang Q., Joseph P., Kabsch W., Kannan Sivaraman K., Klemba M., Komagal Kannan Sivaraman, Lee J., Lew V. L., Li F., Li L., Liguori A., Liu J., Marcin Drag, Massaro A., McGowan S., McGowan S., McGowan S., Meyer G. R., Mucha A., Nyssa Drinkwater, Oshovsky G. V., Peter J. Scammells, Poreba M., Riva E., Rosenthal P. J., Sabine Fletcher, Sang Q., Sasdekumar Loganathan, Schüttelkopf A. W., Shailesh N. Mistry, Sheena McGowan, Sivaraman K. K., Skinner-Adams T. S., Sreedhar B., Stack C. M., Swapna K., Taillefer M., Thomsen R., Tubaro C., Tufariello J. J., Uk Son S., Usachova N., Velmourougane G., Vicky M. Avery, Wadhwa K., Wickstrom M., Xu Z.-L., Zmitek J., Zou B.   +79 more
core   +4 more sources

Preparation of New α-Aminophosphonate Derivatives by Kabachnik-Fields Reaction Using a Recyclable Catalyst

Journal of Chemistry, 2013
A convenient and efficient synthetic method for the preparation of some new α-aminophosphonate derivatives via a one-pot three-component system has been achieved using Amberlite IRC-748 as a recyclable catalyst. This method not only provides an excellent
Nellisara D. Shashikumar
doaj   +1 more source

Synthesis and Antiviral Bioactivities of α-Aminophosphonates Containing Alkoxyethyl Moieties

Molecules, 2006
A simple, efficient, and general method has been developed for the synthesis ofvarious α-aminophosphonate derivatives 4a-4l by treatment of substituted benzaldehydes andaniline with bis(2-methoxyethyl)- or bis(2-ethoxyethyl) phosphite under ...
Zhuo Chen, Linhong Jin, Guiping Ouyang, Ping Lu, Deyu Hu, Wei Xue, Song Yang, Gangfang Xu, Baoan Song, Kai Yan, Yingshu Xu   +10 more
doaj   +1 more source

Tetramethylguanidine (TMG)-catalysed Synthesis of α-Aminophosphonates by a One-pot Reaction [PDF]

, 2015
Aldimines (Schiff’s bases) undergo nucleophilic addition with diethyl/dimethyl/diphenylphosphite (Pudovik reaction) in the presence of a catalytic amount of tetramethylguanidine (TMG) at ambient temperature to afford the corresponding α-aminophosphonates
Kumar, BS, Raju, CN, Reddy, CS, Sankar, AUR   +3 more
core   +1 more source