Results 161 to 170 of about 2,267 (195)

Synthesis of Tetrasubstituted α‐Aminophosphonic Acid Derivatives from Trisubstituted α‐Aminophosphonates

European Journal of Organic Chemistry, 2013
AbstractAn efficient method for the preparation of quaternary α‐aminophosphonic acid derivatives is reported. The nucleophilic addition of organometallic reagents to α‐ketiminophosphonates allows the preparation of quaternary α‐aminophosphonates. The diastereoselective synthesis of a quaternary α‐aminophosphonate using a chiral tartaric‐acid‐derived ...
Javier Vicario, Pablo Ortiz, Francisco Palacios   +2 more
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ChemInform Abstract: α‐AMINOPHOSPHONATES. II. ALKYLATION: SYNTHESIS OF α‐AMINOPHOSPHONIC ACIDS

Chemischer Informationsdienst, 1978
AbstractDie Kondensation des Benzylidenaminomethylphosphonats (I) mit reaktionsfähigen Halogeniden liefert die Monoalkylierungsprodukte (II), die durch neue Alkylierungen disubstituierte Verbindungen wie (III) bilden können.
A. DEHNEL, G. LAVIELLE
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Latest achievements in the preparation of fluorinated aminophosphonates and aminophosphonic acids

Phosphorus, Sulfur, and Silicon and the Related Elements, 2017
The goal of this mini review is to describe advances and achievements, particularly the contributions of the recent years, in synthesis and applications of α-monofluoro-, α,α-difluoro- or trifluoro...
Tomasz Cytlak, Marcin Kaźmierczak, Monika Skibińska, Henryk Koroniak   +3 more
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Aminophosphonates and aminophosphonic acids with tetrasubstituted stereogenic center: diastereoselective synthesis from cyclic ketimines

Organic & Biomolecular Chemistry, 2019
Chiral tetrasubstituted aminophosphonic acid derivatives of hexahydroquinoxalin-2(1H)-one were synthesisedviadiastereoselective hydrophosphonylation of corresponding imines with tris(trimethylsilyl)phosphite as phosphorus nucleophile.
Jakub Iwanejko, Anna Brol, Bartłomiej M. Szyja, Marek Daszkiewicz, Elżbieta Wojaczyńska, Tomasz K. Olszewski   +5 more
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Aminophosphonic Acids of Potential Medical Importance

Current Medicinal Chemistry-Anti-Cancer Agents, 2001
Aminophosphonic acids were almost unknown in 1959 but today they are the subject of more than 6000 papers. Their negligible mammalian toxicity, and the fact that they very efficiently mimic aminocarboxylic acids makes them extremely important antimetabolites, which compete with their carboxylic counterparts for the active sites of enzymes and other ...
P, Kafarski, B, Lejczak
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Synthesis of Peptides Contahng Aminophosphonic Acids

Journal of Pharmaceutical Sciences, 1974
Dipeptides containing C-terminal α-aminobenzylphosphonic acid were prepared in both aqueous and nonaqueous media. The synthesis of intermediates necessary for the preparation of peptides containing α-aminophosphonic acids is also discussed.
W F, Gilmore, H A, McBride
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Aminophosphonic acids: Biosynthesis by marine phytoplankton

Comparative Biochemistry and Physiology, 1969
Abstract 1. 1. Aminophosphonic acids were isolated from a planktonic amphipod and from a plankton sample consisting of phytoplankton and microzooplankton (3 per cent of the total phosphorus). 2. 2. Five species of marine phytoplankters in culture synthesized aminophosphonic acids from 32 P-orthophosphate. 3. 3.
J S, Kittredge, M, Horiguchi, P M, Williams   +2 more
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α-AMINOPHOSPHONATE MONOESTERS IN ONE STEP

Phosphorus, Sulfur, and Silicon and the Related Elements, 1996
N-Substituted α-amino-arylmethyl-phosphonate monoesters have been prepared in moderate to good yields and in a high state of purity by a convenient one-step synthesis. New compounds incorporating the pyridin-2-yl group are prepared and fully characterised. The method described here has also been employed to synthesize two known compounds for comparison.
Bligh SWA, McGrath CM, FAILLA, Salvatore, Finocchiaro P.   +3 more
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Synthesis of β‐Aminophosphonates and ‐Phosphinates

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Francisco, Palacios, Concepción, Alonso, Jesús M, de Los Santos   +2 more
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ChemInform Abstract: Synthesis of Tetrasubstituted α‐Aminophosphonic Acid Derivatives from Trisubstituted α‐Aminophosphonates.

ChemInform, 2014
AbstractAddition reaction of organometallic reagents to tertiary α‐iminophosphonates offers an efficient strategy for the preparation of quaternary α‐aminophosphonates.
Javier Vicario, Pablo Ortiz, Francisco Palacios   +2 more
openaire   +1 more source