Results 21 to 30 of about 2,267 (195)

One-Pot Phosphonylation of Heteroaromatic Lithium Reagents: The Scope and Limitations of Its Use for the Synthesis of Heteroaromatic Phosphonates

Molecules, 2023
A one-pot lithiation–phosphonylation procedure was elaborated as a method to prepare heteroaromatic phosphonic acids. It relied on the direct lithiation of heteroaromatics followed by phosphonylation with diethyl chlorophosphite and then oxidation with ...
Ewa Chmielewska, Natalia Miodowska, Błażej Dziuk, Mateusz Psurski, Paweł Kafarski   +4 more
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Highly Diastereoselective Construction of Carbon– Heteroatom Quaternary Stereogenic Centers in the Synthesis of Analogs of Bioactive Compounds: From Monofluorinated Epoxyalkylphosphonates to α-Fluoro-, β-, or γ-Amino Alcohol Derivatives of Alkylphosphonates

Frontiers in Chemistry, 2021
The synthesis of the stable surrogates of an important amino acid (R)-4-amino-3-hydroxybutyric acid (GABOB) such as substituted hydroxy aminophosphonic acids bearing a quaternary stereogenic center is presented.
Magdalena Rapp, Klaudia Margas-Musielak, Patrycja Kaczmarek, Agnieszka Witkowska, Tomasz Cytlak, Tomasz Cytlak, Tomasz Siodła, Henryk Koroniak   +7 more
doaj   +1 more source

Share on vk Share on google_plusone_share Share on twitter Share on email More Sharing Services Synthesis, acid-base, and complexing properties of ethylenediaminetetra(O-alkyl)methylene­phosphonic acids – the closest organophosphorus analogs of ethylenediaminetetraacetic acid

Учёные записки Казанского университета: Серия Естественные науки, 2022
A number of new complexones – ethylenediaminetetra(O-alkyl)methylenephosphonic acids, the structurally related organophosphorus analogs of ethylenediaminetetraacetic acid – were synthesized.
A.R. Garifzyanov, I.D. Shurygin, I.I. Mirzayanov, F.V. Devyatov   +3 more
doaj   +1 more source

Synthesis, Spectral Characterization of Several Novel Pyrene-Derived Aminophosphonates and Their Ecotoxicological Evaluation Using Heterocypris incongruens and Vibrio fisheri Tests

Molecules, 2016
Four diphenyl pyrene-derived aminophosphonates were synthesized. Attempts were made to synthesize diphenyl N-(R)-α-methylbenzylamino(pyren-1-yl)methylphosphonate (3e) in order to obtain the chiral aminophosphonate bearing a pyrene moiety.
Jarosław Lewkowski, Maria Rodriguez Moya, Marta Chmielak, Diana Rogacz, Kamila Lewicka, Piotr Rychter   +5 more
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α-(Imino)pyridyldifluoroethyl Phosphonates: Novel Promising Building Blocks in Synthesis of Biorelevant Aminophosphonic Acids Derivatives

Organics, 2021
A convenient synthetic approach to previously unknown NH-iminophosphonates bearing 2-, 3-, and 4-pyridyldifluoromethyl groups at the imine carbon atom was developed.
Oksana M. Shavrina, Lyudmyla V. Bezgubenko, Andrii V. Bezdudny, Petro P. Onys’ko, Yuliya V. Rassukana   +4 more
doaj   +1 more source

Addition of Di(trimethylsilyl) Phosphite to Schiff Bases of 2,5-Diformylfuran [PDF]

, 2011
A series of 2,5-Furanyl-bis-(aminomethylphosphonic Acids) has been synthesized by the addition of di(trimethylsilyl) phosphite to azomethine bond of achiral Schiff bases derved from 2,5-diformylfuran.
Ciechańska, Magdalena, Dzięgielewski, Marek, Lewkowski, Jarosław, Szcześniak, Aleksandra   +3 more
core   +1 more source

Chelating Tendencies of Bioactive Aminophosphonates

Metal-Based Drugs, 1994
The metal‐binding abilities of a wide variety of bioactive aminophosphonates, from the simple aminoethanephosphonic acids to the rather large macrocyclic polyaza derivatives, are discussed with special emphasis on a comparison of the analogous carboxylic acid and phosphonic acid systems.
Kiss, Tamas, Lázár, István, Kafarski, Pawel   +2 more
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Physiological Activity of Some Aminophosphonates

Zeitschrift für Naturforschung C, 2001
Abstract Influence of some new am inophosphonates on electrolyte leakage from cucumber (Cucu­-mis sativus cv "Wisconsin") cotyledons as well as on the content of chlorophyll and activity of guaiacol and pyrogallol peroxidase were studied.
K, Bielecki, A, Dziamska, J, Sarapuk
openaire   +2 more sources

Cinchona based squaramide catalysed enantioselective Michael addition of a-nitrophosphonates to aryl acrylates: enantioselective synthesis of quaternary a-aminophosphonates [PDF]

, 2013
Several cinchona based squaramide catalysts were applied to the asymmetric Michael addition of α-nitroethylphosphonates to acrylic acid aryl esters, resulting in high yields and enantioselectivities.
Gönczi, Katalin, Hegedűs, László, Jászay, Zsuzsa, Kardos, György, Kubinyi, Miklós, Kállay, Mihály, Petneházy, Imre, Pham, Truong Son, Szabó, Pál, Süle, Krisztina, Tőke, László   +10 more
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Synthesis of Tetrasubstituted Phosphorus Analogs of Aspartic Acid as Antiproliferative Agents [PDF]

, 2022
An efficient general method for the synthesis of a wide family of α-aminophosphonate analogs of aspartic acid bearing tetrasubstituted carbons is reported through an aza-Reformatsky reaction of α-iminophosphonates, generated from α-aminophosphonates, in ...
Del Corte Solaguren-Beascoa, Xabier, López Francés, Adrián, Maestro Burzaco, Aitor, Palacios Gambra, Francisco Javier, Vicario Hernando, Javier   +4 more
core   +3 more sources