Results 131 to 140 of about 9,787 (160)
Some of the next articles are maybe not open access.
American Journal of Medical Genetics, 1990
AbstractWe studied a baby born with physical features suggestive of the aminopterin syndrome, but without exposure of the mother to aminopterin during pregnancy.G‐banded chromosomes from peripheral blood lymphocytes had a normal 46,XX pattern. However, in 50 skin fibroblasts there was a normal female karyotype in 5 cells and 45 cells showed an ...
M F, Chen +5 more
openaire +2 more sources
AbstractWe studied a baby born with physical features suggestive of the aminopterin syndrome, but without exposure of the mother to aminopterin during pregnancy.G‐banded chromosomes from peripheral blood lymphocytes had a normal 46,XX pattern. However, in 50 skin fibroblasts there was a normal female karyotype in 5 cells and 45 cells showed an ...
M F, Chen +5 more
openaire +2 more sources
Fetus with features of Crane-Heise syndrome and aminopterin syndrome sine aminopterin (ASSAS)
Clinical Dysmorphology, 1994A male fetus with multiple congenital abnormalities is reported. The parents of the fetus are consanguineous. There were unusual facial features, digital anomalies, cleft palate, a malformed tongue that prevented swallowing, absent clavicles and genital hypoplasia.
A J, Barnicoat +2 more
openaire +2 more sources
Teratogenic effects of aminopterin in sheep
Teratology, 1968AbstractSheep were given subcutaneous injections of aminopterin at different times and for different intervals during gestation. Congenital malformations occurred after treatment at all periods. The principal malformations observed were rotational and flexing deformities of the appendicular skeleton, kyphosis, scoliosis, torticollis, aplasia of the ...
L F, James, R F, Keeler
openaire +2 more sources
JAMA, 1962
To the Editor:— It was called to our attention ( JAMA 178 :46 [Oct. 21] 1961) that a misstatement had been made in a correction. In this notation Dr. Kushner commented on an article, Treatment of Reticulosis ( JAMA 175 :84 [Jan. 14] 1961), wherein the dosage of aminopterin was incorrectly stated. We concur that this dosage is incorrect. However, Dr.
openaire +1 more source
To the Editor:— It was called to our attention ( JAMA 178 :46 [Oct. 21] 1961) that a misstatement had been made in a correction. In this notation Dr. Kushner commented on an article, Treatment of Reticulosis ( JAMA 175 :84 [Jan. 14] 1961), wherein the dosage of aminopterin was incorrectly stated. We concur that this dosage is incorrect. However, Dr.
openaire +1 more source
Intrathecal Aminopterin Therapy of Meningeal Leukemia
Archives of Internal Medicine, 1963Meningeal leukemia is an important complication of acute leukemia. 3 While chemotherapy has resulted in prolongation of survival, 4 the effective antimetabolites do not reach therapeutic levels in the cerebrospinal fluid. 5,6 As a result, meningeal leukemia has become the major therapeutic problem in patients with acute leukemia in remission, as well ...
R E, RIESELBACH +4 more
openaire +2 more sources
EFFECT OF "AMINOPTERIN" ON EPITHELIAL TISSUES
Archives of Dermatology, 1951The folic acid antagonist, 4-aminopteroyl glutamic acid ("aminopterin"), is a potent inhibitor of growth and of connective tissue proliferation. The present study indicates that the suppressive effects of "aminopterin" on epithelial structures are more striking than on connective tissue, as revealed by observation of interference with wound healing and
openaire +3 more sources
Maternal Aminopterin Ingestion-Reply
Archives of Pediatrics & Adolescent Medicine, 1973The correspondents are correct in doubting my doubts about aminopterin and thalidomide effects on the brain. Aminopterincancause malformations of the brain in human embryos as shown by Thiersch (Acta Endocrinol, suppl 28:37, 1956) and thalidomide has been held responsible for damage to the central nervous system (Horstmann W,Z Kinderheilkd96:291, 1966)
openaire +1 more source