Results 91 to 100 of about 28,342 (216)

Chelate-modified polymers for atmospheric gas chromatography [PDF]

, 1980
Chromatographic materials were developed to serve as the stationary phase of columns used in the separation of atmospheric gases. These materials consist of a crosslinked porous polymer matrix, e.g., a divinylbenzene polymer, into which has been embedded
Christensen, W. W., Mayer, L. A., Woeller, F. H.   +2 more
core   +1 more source

Late expression of FosB transcription factor in 4-aminopyridine-induced seizures in the rat cerebral cortex [PDF]

, 2008
In order to deliver services to citizens, public sector agencies of today offer various types of channels for interaction. In this article we aim to develop an understanding of the reciprocal relation between multi‑channel services and work prac tice. By
Bagosi, Andrea, Fejesné Bakos, Mónika, Krisztin-Péva, Beáta, Mihály, András   +3 more
core   +1 more source

Blebbistatin reduces calcium buffering in cardiomyocytes: Consequences for cellular electrophysiology

The Journal of Physiology, EarlyView.
Abstract figure legend Blebbistatin reduces Ca2+ buffering in induced pluripotent stem cell‐derived atrial cardiomyocytes. Blebbistatin, a widely used excitation–contraction uncoupling agent, decreases calcium (Ca2+) buffer affinity (increased buffer dissociation constant), leading to elevated diastolic Ca2+ levels, increased sarcoplasmic reticulum Ca2+
Izzatullo Sobitov, Katharina Ritzenhoff, Marie Gaulrapp, Lea Becker, Aiste Liutkute, Fitzwilliam Seibertz, Funsho E. Fakuade, Fleur E. Mason, Niels Voigt   +8 more
wiley   +1 more source

Amiodarone reduces depolarization-evoked glutamate release from hippocampual synaptosomes

Journal of Pharmacological Sciences, 2017
Decreased brain glutamate level has emerged as a new therapeutic approach for epilepsy. This study investigated the effect and mechanism of amiodarone, an anti-arrhythmic drug with antiepileptic activity, on glutamate release in the rat hippocampus. In a
Chia Yu Chang, Chi Feng Hung, Shu Kuei Huang, Jinn Rung Kuo, Su Jane Wang   +4 more
doaj   +1 more source

Glutamate-mediated blood-brain barrier opening. implications for neuroprotection and drug delivery [PDF]

, 2016
The blood-brain barrier is a highly selective anatomical and functional interface allowing a unique environment for neuro-glia networks. Blood-brain barrier dysfunction is common in most brain disorders and is associated with disease course and delayed ...
CECCANTI , MARCO, Chassidim, Y, COLONNESE, Claudio, D'ELIA, ALESSANDRO, Fassler, M, Friedman, A., INGHILLERI, Maurizio, Nucciarelli, V, ONESTI, EMANUELA, Pell, Gs, Prager, O, Raccah, R, Roth, Y, SALVATI, Maurizio, SANTORO, Antonio, Shahar, H, Vazana, U, Veksler, R, Zangen, A   +18 more
core   +1 more source

The sympathoregulatory region of the mouse rostral brainstem relies on both GABA and glycine to generate inhibitory currents

The Journal of Physiology, EarlyView.
Abstract figure legend Our study demonstrates that both GABA and glycine mediate inhibitory postsynaptic currents in the ventrolateral/ventromedial medulla (VLM/VMM) and increasing the activity of inhibitory synapses facilitates glycine release. We found that presympathetic VLM/VMM neurons receive glycinergic inputs, which release both glycine and GABA,
Hong Gao, Lucie D. Desmoulins, Adrien J. R. Molinas, Courtney M. Dugas, Andrea Zsombok, Andrei V. Derbenev   +5 more
wiley   +1 more source

Role of K+ Channels in M2 Muscarinic Receptor-Mediated Inhibition of Noradrenaline Release From the Rat Stomach

Journal of Pharmacological Sciences, 2004
Previously we reported the cholinergic M2 muscarinic receptor-mediated inhibition of noradrenaline release from the rat stomach (K. Yokotani, Y. Osumi. J Pharmacol Exp Ther. 1993;264:54–60).
Kumiko Nakamura, Shoshiro Okada, Naoko Yamaguchi, Takahiro Shimizu, Keiko Yokotani, Kunihiko Yokotani   +5 more
doaj   +1 more source

Cellular antiseizure mechanisms of everolimus in pediatric tuberous sclerosis complex, cortical dysplasia, and non-mTOR-mediated etiologies. [PDF]

, 2018
The present study was designed to examine the potential cellular antiseizure mechanisms of everolimus, a mechanistic target of rapamycin (mTOR) pathway blocker, in pediatric epilepsy cases. Cortical tissue samples obtained from pediatric patients (n 
Barry, Joshua, Cepeda, Carlos, Fallah, Aria, Levine, Michael S, Levinson, Simon, Mathern, Gary W, Vinters, Harry V, Wu, Joyce Y, Yazon, Vannah-Wila   +8 more
core   +2 more sources

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source

Octaakis(4-aminopyridine)-1κ4N1,2κ4N1-aqua-2κO-μ-carbonato-1:2κ3O,O′:O′′-dinickel(II) dichloride pentahydrate

Acta Crystallographica Section E, 2008
In the title compound, [Ni2(CO3)(C5H6N2)8(H2O)]Cl2·5H2O, one of the the NiII ions is six-coordinated in a distorted octahedral geometry, with the equatorial plane defined by four pyridine N atoms from four aminopyridine ligands, the axial positions ...
Hoong-Kun Fun, A Sinthiya, Samuel Robinson Jebas, B. Ravindran Durai Nayagam, S. Alfred Cecil Raj   +4 more
doaj   +1 more source