Results 61 to 70 of about 28,342 (216)

The contribution of ionic currents to changes in refractoriness of human atrial myocytes associated with chronic atrial fibrillation [PDF]

open access: yes, 2001
<b>Objective:</b> To investigate changes in human atrial single cell functional electrophysiological properties associated with chronic atrial fibrillation (AF), and the contribution to these of accompanying ion current changes.
Kane, K.A., Rankin, A.C., Workman, A.J.
core   +1 more source

Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo

open access: yesChemistry – A European Journal, EarlyView.
This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova   +2 more
wiley   +1 more source

Diphenyl[2-(2-pyridylaminomethyl)phenyl]phosphine oxide

open access: yesActa Crystallographica Section E, 2010
The title compound, C24H21N2OP, was obtained by reacting 2-aminopyridine and 2-(diphenylphosphinyl)benzaldehyde in ethanol. It crystallizes with two crystallographically independent molecules in the asymmetric unit.
Sim&#243;n Hern&#225;ndez-Ortega   +2 more
doaj   +1 more source

Rapid protium-deuterium exchange of 4-aminopyridines in neutral D2O under microwave irradiation [PDF]

open access: yes, 2016
4-Aminopyridines undergo surprisingly rapid and highly-selective H/D exchange at C-2 and C-6 in neutral D2O upon microwave irradiation at only 190 °C for 2 h in a sealed vessel.
Alnomsy, Ayed   +2 more
core   +1 more source

Behavioral and epileptic phenotypes in a CHD2‐related developmental delay model

open access: yesEpilepsia, EarlyView.
Abstract Objective Heterozygous loss‐of‐function mutations in the CHD2 gene, encoding chromodomain helicase DNA‐binding protein 2, are associated with severe childhood onset epilepsy, global developmental delay, and autistic features. Animal models that accurately recapitulate human phenotypes are crucial for understanding rare neurodevelopmental ...
Anat Mavashov   +10 more
wiley   +1 more source

Synthesis, Characterization and Antibacterial Properties of Complex [Ag(SCN)(2-NH2py)] [PDF]

open access: yesE3S Web of Conferences
The reaction of AgSCN with 2-aminopyridine in ammonia solution produces the colorless crystal of catena-poly [Ag(SCN))(C6H5N2)]n. The crystals were characterized by FTIR analysis and single crystal X-Ray diffraction.
Mariyam Dewi   +3 more
doaj   +1 more source

Human sperm ion channel (dys)function:implications for fertilization [PDF]

open access: yes, 2019
BACKGROUND: Intensive research on sperm ion channels has identified members of several ion channel families in both mouse and human sperm. Gene knock-out studies have unequivocally demonstrated the importance of the calcium and potassium conductances in ...
Barratt, Christopher L. R.   +3 more
core   +4 more sources

Targeting Hsp90 with cemdomespib reduces seizure burden and alters disease course in preclinical epilepsy models

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy is a chronic neurological disorder characterized by recurrent seizures and frequent cognitive and psychiatric comorbidities. Although current antiseizure medications provide symptomatic relief, they fail to prevent or modify epileptogenesis.
Yara Sheeni   +8 more
wiley   +1 more source

Hydrogen bonding patterns in the cocrystals of 5-nitrouracil with several donor and acceptor molecules

open access: yesBeilstein Journal of Organic Chemistry, 2005
Cocrystals of 5-nitrouracil with solvent molecules, dioxane, pyridine, DMSO, formamide and ethanol as well as with piperazine, N, N'-dimethylpiperazine, 3-aminopyridine and diazabicyclo [2.2.2]octane obtained by deliberate inclusion, have been examined ...
Reji Thomas   +3 more
doaj   +1 more source

catena-Poly[[silver(I)-&#956;-4-aminopyridine] perchlorate]: a 1-D staircase coordination polymer

open access: yesActa Crystallographica Section E, 2010
Reaction of 4-aminopyridine with silver(I) perchlorate leads to a one-dimensional coordination polymer, {[Ag(C5H6N2)]ClO4}n, in which the aminopyridine binds through both N atoms.
Peter J. Steel   +3 more
doaj   +1 more source

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