Results 151 to 160 of about 2,316 (194)
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The mechanism of myeloperoxidase-catalysed oxidation of aminopyrine
Xenobiotica, 19901. Myeloperoxidase catalysed the H2O2-supported oxidation of aminopyrine in the presence of Cl-, generating the aminopyrine cation radical (AP+.). The rate of AP+. formation was determined by monitoring the absorbance at 565 nm. The pH optimum of the reaction was around 5.0. The rate of AP+.
H, Sayo, M, Saito
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Kinetics of the nitrosation of aminopyrine to give dimethylnitrosamine
Zeitschrift f�r Krebsforschung und Klinische Onkologie, 1974The initial rate of nitrosation of aminopyrine (AP, Pyramidon) to give dimethyl nitrosamine (DMN) showed maxima at pH 2.0 and 3.1. At pH 2, initial rate was proportional to nitrite concentration squared down to 6 mM, below which it decreased rapidly.
S S, Mirvish +3 more
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Acute Renal Failure Caused by Aminopyrine
JAMA, 1964AMINOPYRINE is one of the more potent of the nonnarcotic analgesics and antipyretics.1Its once extensive use has diminished markedly because of its toxic effects on the bone marrow which produce leukopenia, neutropenia, and agranulocytosis, and sometimes result in death.2In a special report of the Council on Pharmacy and Chemistry of the American ...
G, EKNOYAN, J L, MATSON
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Determinants of hepatic aminopyrine demethylase activity
Biochemical Pharmacology, 1969Abstract A study has been made of age and maturational determinants as well as of the incubation conditions which effect aminopyrine demethylase activity of rat liver. The specific activity of N -demethylation in vitro by the 9000 g supernatant fraction increased about 3-fold in the first 30 days after birth.
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[Mechanism of the action aminopyrine].
Farmakologiia i toksikologiia, 1976In acute experiments on unanesthetized cats with a single and paired stimulation the effect of aminopyrine (5-30 mg/kg, intravenously) on bioelectric reactions in the conduction system of afferent impulsation at the thalamo-cortical level was studied. Aminopyrine is shown to highten the amplitude of an evoked potential of the somato-sensory cortex and ...
M V, Komendantova, G M, Aleksandrova
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The Determination of Aminopyrine and Dipyrone Metabolites
Therapeutic Drug Monitoring, 1996E, Zylber-Katz, M, Levy
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Aminopyrine and blood dyscrasias
Pharmacoepidemiology and Drug Safety, 1997David W. Kaufman, Surapol Issaragrisil
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