Results 51 to 60 of about 15,403 (210)

Lupus-Like Syndrome Caused by 5-Aminosalicylic Acid in Patients with Inflammatory Bowel Disease

open access: yesCanadian Journal of Gastroenterology, 1999
BACKGROUND: Although 5-aminosalicylic acid (5-ASA) preparations used to treat inflammatory bowel disease are reported to have fewer side effects than sulphasalazine, increased clinical use of these compounds has resulted in increased reports of ...
Andrew W Kirkpatrick   +2 more
doaj   +1 more source

Asian Pacific Association of Gastroenterology (APAGE) Clinical Practice Guidelines on the Use of Small Molecules and IL‐23 p19 Inhibitors in Ulcerative Colitis and Crohn's Disease

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Ulcerative colitis (UC) and Crohn's disease (CD) are increasingly prevalent in the Asia Pacific region, necessitating updated, region‐specific guidance on advanced therapies. Targeted small molecule agents, such as filgotinib, tofacitinib, upadacitinib, etrasimod, and ozanimod; and the IL‐23 p19 inhibitors (guselkumab, mirikizumab ...
Choon Jin Ooi   +34 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Preparation and evaluation of magnetic microspheres of mesalamine (5-aminosalicylic acid) for colon drug delivery

open access: yesJournal of Acute Disease, 2013
Objective: To study magnetic microspheres of mesalamine (5-aminosalicylic acid) for colon drug delivery. Methods: Magnetic microspheres were prepared by solvent evaporation technique for use in the application of magnetic carrier technology.
Satinder Kakar   +2 more
doaj   +1 more source

Development of a 3D‐Printed Electrochemical Platform With Dual Working Electrodes for Mesalamine Detection

open access: yesAnalysis &Sensing, Volume 6, Issue 4, July 2026.
This work presents a fully 3D‐printed, low‐cost multiplexed electrochemical platform with dual working electrodes for mesalamine detection. Chemical/electrochemical activation enhances electrode performance, enabling sensitive and reproducible quantification in biological matrices.
Mariana A. de Jesus   +8 more
wiley   +1 more source

Crystal structures and hydrogen bonding in the co-crystalline adducts of 3,5-dinitrobenzoic acid with 4-aminosalicylic acid and 2-hydroxy-3-(1H-indol-3-yl)propenoic acid

open access: yes, 2014
The structures of the co-crystalline adducts of 3,5-dinitrobenzoic acid (3,5-DNBA) with 4-aminosalicylic acid (PASA), the 1:1 partial hydrate, C7H4N2O6·C7H7NO3·0.2H2O, (I), and with 2-hydroxy-3-(1H-indol-3-yl)propenoic acid (HIPA), the 1:1:1 d6-dimethyl ...
Daniel E. Lynch   +3 more
core   +1 more source

Risk factors for adverse events in patients with multidrug-resistant tuberculosis, HIV-infection and viral hepatitis C

open access: yesТерапевтический архив
Aim. To identify risk factors for adverse drug reactions (ADRs) in patients co-infected with multidrug-resistant tuberculosis (MDR-TB), HIV and viral hepatitis C (HCV). Materials and methods.
Anastasiia V. Kukurika
doaj   +1 more source

Scutellarein Alleviates Ulcerative Colitis by Reshaping Gut Microbiota and Regulating the PRMT1‐Mediated Th17/Treg Balance

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Scutellarein alleviates ulcerative colitis by reinforcing the intestinal barrier via the microbiota‐metabolite axis and suppressing PRMT1‐STAT3‐mediated inflammatory immune responses. ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colonic mucosa with an increasing global burden and limited therapeutic efficacy.
Yefan Zhou   +12 more
wiley   +1 more source

The culprit of mesalamine intolerance: case series and literature review

open access: yesBMC Gastroenterology, 2019
Background Mesalamine is a first-line drug in the treatment of inflammatory bowel diseases, while its intolerance occasionally occurs in clinical practice.
Cheng Xie   +5 more
doaj   +1 more source

Apple Pomace Pectin for Gastroprotective Nutraceutical Delivery: Structure–Function Relationships and Nano/Microencapsulation Strategies for Gastric Ulcer Management

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman   +6 more
wiley   +1 more source

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