Results 91 to 100 of about 44,264 (223)

Mechanistic insights into sex differences in atrial electrophysiology and arrhythmia vulnerability through sex‐specific computational models

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sex‐specific models of the human atrial myocyte in normal sinus rhythm (nSR) and chronic atrial fibrillation (cAF) revealed increased alternans susceptibility in cAF males and DADs in females, driven primarily by ICaL and ryanodine receptor remodelling.
Nathaniel T. Herrera   +6 more
wiley   +1 more source

Machine learning methods for predicting adverse drug events: A systematic review

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 422-444, February 2026.
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo   +8 more
wiley   +1 more source

Drug‐Induced QT Prolongation: Associations Between Risk Classifications in a Swedish Clinical Decision Support System and Clinical Outcomes

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 503-513, February 2026.
Potential adverse drug events can be signaled in Clinical Decision Support Systems (CDSSs). This study validated a Swedish CDSS (Janusmed Risk Profile) by investigating associations between calculated risk classifications of drugs with QT‐prolonging potential and registered related clinical outcomes.
Ola Nordqvist   +6 more
wiley   +1 more source

Perioperative Intravenous Amiodarone Does Not Reduce the Burden of Atrial Fibrillation in Patients Undergoing Cardiac Valvular Surgery [PDF]

open access: bronze, 2009
Yanick Beaulieu   +10 more
openalex   +1 more source

A retrospective study on laboratory‐confirmed acute Chinese medicine poisoning involving aconite in Hong Kong from 2008 to 2020

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 1, February 2026.
Abstract Background Territory‐wide epidemiological studies of acute Chinese medicine poisoning involving aconite after 2010 are lacking. Objectives To characterise the latest trends, presumed causes, clinical presentations, healthcare utilisation and patient outcomes of such poisoning cases in Hong Kong.
Rex Pui Kin Lam   +9 more
wiley   +1 more source

Amiodarone exacerbates brain injuries after hypoxic–ischemic insult in mice

open access: yesBMC Neuroscience, 2019
Background Sodium ion transportation plays a crucial role in the pathogenesis of hypoxic–ischemic brain injury. Amiodarone, a Vaughan-Williams class III antiarrhythmic drug, has been widely used to treat life-threatening arrhythmia and cardiac arrest ...
Masakazu Kotoda   +4 more
doaj   +1 more source

AMIODARONE HYDROCHLORIDE [PDF]

open access: yesAustralian and New Zealand Journal of Ophthalmology, 1986
G M, Eckert, R F, Taylor, M D, Steiner
openaire   +2 more sources

Current Trends in Duchenne Muscular Dystrophy Research and Therapy: 3D Cardiac Modelling

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, presents a multifaceted challenge that affects both skeletal muscle function and cardiomyocyte homeostasis, causing progressive degeneration and life‐threatening cardiac complications by adolescence.
Marta Przymuszała   +3 more
wiley   +1 more source

High concentration Amiodarone continuous infusion induced Phlebitis: A Case Report

open access: diamond, 2023
Madhusoodan M Gonenavar   +4 more
openalex   +2 more sources

Safety and Efficacy of Pulsed Field Ablation for Atrial Fibrillation in Elderly Patients

open access: yesJournal of Arrhythmia, Volume 42, Issue 1, February 2026.
Pulsed‐field ablation (PFA) was evaluated in 479 patients with atrial fibrillation (AF), 52% paroxysmal. Among 104 patients > 75 years, complication rates and 6‐ and 12‐month arrhythmia‐free survival were not significantly different from younger patients. Age did not predict recurrence. PFA appears safe and effective in elderly AF patients.
Federico Follesa   +8 more
wiley   +1 more source

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