Results 71 to 80 of about 42,119 (250)

Host-directed therapy with amiodarone in preclinical models restricts mycobacterial infection and enhances autophagy

Microbiology Spectrum
Mycobacterium tuberculosis (Mtb) as well as nontuberculous mycobacteria are intracellular pathogens whose treatment is extensive and increasingly impaired due to the rise of mycobacterial drug resistance.
Gül Kilinç, Ralf Boland, Matthias T. Heemskerk, Herman P. Spaink, Mariëlle C. Haks, Michiel van der Vaart, Tom H. M. Ottenhoff, Annemarie H. Meijer, Anno Saris   +8 more
doaj   +1 more source

Subacute Thyroiditis in Denmark: A Nationwide Study of 1763 Cases

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Subacute thyroiditis (SAT) is a differential diagnosis in the clinical care of hypo‐ and hyperthyroid patients, but large‐scale population data on the incidence, patient characteristics, and outcome are limited. Thus, the aim was to determine the incidence of SAT in the Danish population and to characterise patient demographics and ...
Marco Juul Thomsen, Niels Henrik Bruun, Nanna Maria Uldall Torp, Jesper Karmisholt, Stig Andersen, Stine Linding Andersen   +5 more
wiley   +1 more source

Amiodarone pulmonary toxicity: a report on two cases

Southwest Respiratory and Critical Care Chronicles, 2015
Amiodarone is an iodine-containing antiarrhythmic drug commonly used for the treatment of ventricular and supraventricular arrhythmias. Amiodarone toxicity has several clinical presentations and affects multiple organs. One well-known serious side effect
Ahmed Zedan, Osama Mukarram, Charles E. Burns, Yasir Ahmed   +3 more
doaj  

Inhibition of ATP-Sensitive K+ Channels and L-Type Ca2+ Channels by Amiodarone Elicits Contradictory Effect on Insulin Secretion in MIN6 Cells

Journal of Pharmacological Sciences, 2011
.: Some class I antiarrhythmic drugs induce a sporadic hypoglycemia by producing insulin secretion via inhibition of ATP-sensitive K+ (KATP) channels of pancreatic β-cells.
Atsushi Nishida, Taichi Takizawa, Akio Matsumoto, Takashi Miki, Susumu Seino, Haruaki Nakaya   +5 more
doaj   +1 more source

Diagnostic Options in Graves' or Non‐Graves' Thyrotoxicosis: A Review for Clinical Practice

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Distinguishing Graves' disease (GD) from the other causes of thyrotoxicosis is essential for appropriate management. The clinical phenotype of GD has evolved over time and is currently more heterogenous and milder than in the past. Consequently, the differential diagnosis of thyrotoxicosis is often challenging.
Lorenzo Scappaticcio, Pierpaolo Trimboli, Paola Caruso, Chiara Porcellini, Daniela Forestiere, Maria Ida Maiorino, Katherine Esposito, Giuseppe Bellastella   +7 more
wiley   +1 more source

Mental Health Disorders in End‐Stage Kidney Disease: A Narrative Review of Clinical Considerations for Integrated Management

Hemodialysis International, EarlyView.
ABSTRACT Introduction End stage kidney disease (ESKD) is associated with a high prevalence of depression and anxiety, arising from both biological factors and the psychosocial burden of chronic dialysis care. Approximately 25%–30% of dialysis patients experience clinically significant depressive symptoms when assessed by structured clinical interview ...
Kunal Malhotra, Jordan Fangue‐Nelon, Garima Singh   +2 more
wiley   +1 more source

The distance between hospitals

Journal of Hospital Medicine, EarlyView.
Carrie A. Sailer
wiley   +1 more source

Single‐Cell Transcriptomics and Mendelian Randomization Analysis Reveal Key Genes in Atrial Fibrillation

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Atrial fibrillation (AF) is one of the most common cardiac arrhythmias. It reduces quality of life and increases the risk of complications such as stroke. Although progress has been made in understanding its pathogenesis, the key cellular subtypes and therapeutic targets remain unclear. Methods We applied single‐cell transcriptomics
Xiangpeng Chen, Hongquan Chen, Shiguang Xu, Shumin Wang, Huishan Wang, Hao Meng   +5 more
wiley   +1 more source

Subclinical Hypothyroidism after a Three-Month Course of Low-Dose Amiodarone. [PDF]

This case report describes a 64-year-old male who developed subclinical hypothyroidism after three months of low-dose amiodarone (100 mg/day). Routine monitoring showed a TSH increase to 44.40 mU/L with normal FT4 and FT3 levels.
Aidana Butabayeva, Nauryzbay Bekishuly, Aya Aitpayeva, Rano Kirkimbayeva, Olzhas Yesseneyev, Zhansaya Yerkhanova, Assel Chinybayeva, Ayan Abdrakhmanov, Bakyt Iskakova, Galiya Smailova, Diana Aibulova, Telman Seisembekov   +11 more
core   +2 more sources

Intravenous Amiodarone

Journal of the American College of Cardiology, 1997
Intravenous amiodarone was approved in 1995 for the treatment of malignant and resistant ventricular arrhythmia. Although it is an "old drug," much has been learned recently about this complex drug and its application in a variety of cardiac arrhythmias.
Kowey, Peter R, Marinchak, Roger A, Rials, Seth J, Filart, Roland A   +3 more
openaire   +2 more sources