Results 61 to 70 of about 59,816 (256)

Fetal tachycardia: A role for amiodarone as first- or second-line therapy? [PDF]

, 2008
SummaryBackgroundFetal tachycardias result in serious prenatal and postnatal morbidity and mortality. Intrauterine treatment can improve prognosis dramatically and the therapeutic protocol is well defined.
Pézard, Philippe Georges, Boussion, Françoise, Sentilhes, Loïc, Lépinard, Catherine, Couvreur, Marie-Hélène, Victor, Jacques, Geslin, Philippe, Descamps, Philippe   +7 more
core   +4 more sources

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

Interaction between warfarin and short-term intravenous amiodarone in intensive care unit patients after cardiac surgery

Journal of Pharmaceutical Health Care and Sciences, 2018
Background Amiodarone and warfarin are sometimes administered immediately after cardiac surgery. Although the interaction between long-term oral amiodarone and warfarin has been reported, the interaction between warfarin and short-term intravenous ...
Tomoki Takase, Hiroaki Ikesue, Makiko Tohi, Hiroshi Ueta, Hiroyuki Mima, Tadaaki Koyama, Tohru Hashida   +6 more
doaj   +1 more source

The interplay between molecular architecture, pharmacology, and suspected adverse drug reactions associated with nonsteroidal androgen antagonists in the United Kingdom

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to correlate potential links between the suspected adverse drug reaction (ADR) profile of licensed nonsteroidal androgen receptor antagonists (NSARA) with their unique chemical properties and known off‐target polypharmacology. Methods Physicochemical and polypharmacology data were curated from the Electronic Medicines Compendium ...
Simrit Dhillon, Albert A. Antolin, Alan M. Jones   +2 more
wiley   +1 more source

Amiodarone‐Induced Pulmonary Toxicity With Confirmed Elevated Plasma Mono‐Desethyl‐Amiodarone Levels

Respirology Case Reports
Amiodarone hydrochloride is an effective antiarrhythmic drug that can cause serious adverse effects, including amiodarone‐induced pulmonary toxicity (APT).
Munechika Hara, Miki Kato, Fumika Sugiyama, Ryo Ichikawa, Tsutomu Hachiya   +4 more
doaj   +1 more source

Amiodarone-Induced Pulmonary Toxicity in a Patient With Paroxysmal Atrial Fibrillation and Recurrence of Pulmonary Toxicity

Van Tıp Dergisi, 2022
Amiodarone is an effective anti-arrhythmic agent widely used for management of supraventricular and ventricular arrhythmias. Amiodarone-induced pulmonary toxicity is one of the most serious side effects of amiodarone therapy.
Nuri Köse, Tarık Yıldırım
doaj   +1 more source

A fatal case of recurrent amiodarone-induced thyrotoxicosis after percutaneous tracheotomy: a case report [PDF]

, 2007
Background Amiodarone is a widely used antiarrythmic drug, which may produce secondary effects on the thyroid. In 14–18% of amiodarone-treated patients, there is overt thyroid dysfunction, usually in the form of amiodarone-induced thyrotoxicosis, which ...
Vasilios Papaioannou, Irene Terzi, Christos Dragoumanis, Dimitrios Konstantonis, Vassiliki Theodorou, Ioannis Pneumatikos, SB Seminara, D Conen, E Martino, DW Holt, A Burger, L Bartalena, C Iudica-Souza, S Brogioni, SEM Eaton, L Bartalena, AP Farwell, F Bogazzi, E Hamoir, J Gough, F Osman, P Weiner, J Hansen-Flaschen, P Camus, GR Bernard, AJ O'Sullivan, C Panzer   +26 more
core   +1 more source

Optimal model‐based design of experiments for parameter precision: Supercritical extraction case

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract This study investigates the process of chamomile oil extraction from flowers. A parameter‐distributed model consisting of a set of partial differential equations is used to describe the governing mass transfer phenomena in a cylindrical packed bed with solid chamomile particles under supercritical conditions using carbon dioxide as a solvent ...
Oliwer Sliczniuk, Pekka Oinas
wiley   +1 more source

Neuroprotective effects of amiodarone in a mouse model of ischemic stroke

BMC Anesthesiology, 2017
Background Ion channels play a crucial role in the development of ischemic brain injury. Recent studies have reported that the blockade of various types of ion channels improves outcomes in experimental stroke models.
Masakazu Kotoda, Tadahiko Ishiyama, Kazuha Mitsui, Sohei Hishiyama, Takashi Matsukawa   +4 more
doaj   +1 more source

Drug Critical Limits for Urgent Physician Notification

Clinical Pharmacology &Therapeutics, EarlyView.
Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang, Yasmeen Ibrahim, Kyle Cheng, Gerald J. Kost   +3 more
wiley   +1 more source