Results 31 to 40 of about 44,264 (223)

Antiarrhythmic Properties of a Prior Oral Loading of Amiodarone in In Vivo Canine Coronary Ligation/Reperfusion-Induced Arrhythmia Model: Comparison With Other Class III Antiarrhythmic Drugs

Journal of Pharmacological Sciences, 2005
Amiodarone, which is generally classified as class III antiarrhythmic drug in the Vaughan Williams classification, is widely used for the treatments of refractory arrhythmias.
Yoshinobu Nagasawa, Jianguang Chen, Keitaro Hashimoto   +2 more
doaj   +1 more source

aMplitude spectral area of ventricular fibrillation and amiOdarone Study in patients with out-of-hospital cArdIaC arrest. The MOSAIC study

Frontiers in Cardiovascular Medicine, 2023
ObjectiveAntiarrhythmic drugs are recommended for out of hospital cardiac arrest (OHCA) with shock-refractory ventricular fibrillation (VF). Amplitude Spectral Area (AMSA) of VF is a quantitative waveform measure that describes the amplitude-weighted ...
Francesca Romana Gentile, Francesca Romana Gentile, Lars Wik, Lars Wik, Elisabete Aramendi, Enrico Baldi, Iraia Isasi, Jon Erik Steen-Hansen, Sara Compagnoni, Sara Compagnoni, Alessandro Fasolino, Alessandro Fasolino, Enrico Contri, Alessandra Palo, Roberto Primi, Sara Bendotti, Alessia Currao, Simone Savastano   +17 more
doaj   +1 more source

Amiodarone photoreactions

Acta Dermato-Venereologica, 1987
Four patients with photoreactions after Amiodarone therapy are described. The action spectrum for photosensitivity was found in the UVA region. Pigmentation seems to be due to wavelengths below 360 nm.
G, Roupe, O, Larkö, S B, Olsson
openaire   +2 more sources

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Too Little, Too Late: A Case of a Swift Fatal Culmination of Amiodarone Induced Pulmonary Toxicity in an Adult Male

International Medical Case Reports Journal, 2023
Clement Tan, Pranav Kumar Department of Respiratory Medicine, Mackay Base Hospital, Mackay, Queensland, AustraliaCorrespondence: Clement Tan; Pranav Kumar, Email Clement.Tan@health.qld.gov.au; Pranav.Kumar@health.qld.gov.auAbstract: Amiodarone is a ...
Tan C, Kumar P
doaj  

Continuous electrocardiogram monitoring in porcine model of myocardial ischemia reperfusion

Animal Models and Experimental Medicine, EarlyView.
Wearable technology for continuous electrocardiogram monitoring can be utilized in porcine models of disease. Abstract As cardiovascular disease is the leading cause of global mortality, innovative animal models are vital to demonstrating the translational value of experimental discoveries. Investigations focused on myocardial remodeling after ischemia
Nathaniel Hyams, Roxanne Swagel, Sharon Thomas, Rupak Mukherjee, Alicia Braxton Hickman, Daniel Eldridge, Kristine Helke, Ying Mei, Jean Marie Ruddy   +8 more
wiley   +1 more source

Amiodarone as an Antiarrhythmia Therapy can Induce Acute Renal Failure in Patiens with SupraventricularTachycardia (SVT): A Rare Case Report

Jurnal Kesehatan Andalas
Amiodarone is classified as a class III antiarrhythmic agent that primarily inhibits adrenergic stimulation by blocking alpha and beta-adrenergic receptors.
Melany Nurjanah, Haryadi Haryadi
doaj   +1 more source

Neuroprotective effects of amiodarone in a mouse model of ischemic stroke

BMC Anesthesiology, 2017
Background Ion channels play a crucial role in the development of ischemic brain injury. Recent studies have reported that the blockade of various types of ion channels improves outcomes in experimental stroke models.
Masakazu Kotoda, Tadahiko Ishiyama, Kazuha Mitsui, Sohei Hishiyama, Takashi Matsukawa   +4 more
doaj   +1 more source

Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation using antiarrhythmic drugs: An international cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Our international cohort study assessed the comparative effectiveness and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) among patients with non‐valvular atrial fibrillation (NVAF) using antiarrhythmic drugs. Methods Using the United Kingdom's (UK's) Clinical Practice Research Datalink Aurum and Québec claims data, we
Fabian Maximilian Meinert, Jenny Dimakos, Ying Cui, Kristian B. Filion, Christel Renoux, Antonios Douros   +5 more
wiley   +1 more source

L-Carnitine Ameliorates Amiodarone-Mediated Alveolar Damage: Oxidative Stress Parameters, Inflammatory Markers, Histological and Ultrastructural Insights

Pharmaceuticals
The aim of this study was to assess L-carnitine’s effects on adult male rats’ lung damage brought on by amiodarone, which is a potent antiarrhythmic with limited clinical efficacy due to potentially life-threatening amiodarone-induced lung damage ...
Samy A. Dawood, Ali Alsuheel Asseri, Ayed A. Shati, Refaat A. Eid, Basiouny El-Gamal, Mohamed Samir A. Zaki   +5 more
doaj   +1 more source