Results 91 to 100 of about 27,203 (239)

Efficacy of a Transdiagnostic Sleep and Circadian Intervention for Outpatients With Sleep Problems and Depression, Attention Deficit Disorder, or Bipolar Disorder: A Randomised Controlled Trial

open access: yesJournal of Sleep Research, Volume 35, Issue 1, February 2026.
ABSTRACT This study aimed to investigate the efficacy of a Danish adaption of a transdiagnostic sleep and circadian intervention, combining cognitive behavioural therapy for insomnia with chronotherapy. A randomised controlled trial enrolling 88 outpatients with depression, attention deficit disorder, or bipolar disorder suffering from insomnia or ...
Mette Kragh   +5 more
wiley   +1 more source

Treatment Preferences in Patients With Insomnia and Medical Comorbidity: Associated Factors and Impact on Treatment‐Outcome

open access: yesJournal of Sleep Research, Volume 35, Issue 1, February 2026.
ABSTRACT Insomnia is common in patients with medical comorbidity. First‐line treatment for insomnia is cognitive behavioural therapy for insomnia (CBT‐I). However, some patients with medical comorbidities prefer pharmacological treatment. This study aimed to (1) identify factors influencing treatment preference in these patients, and (2) assess how ...
Nynke Rauwerda   +7 more
wiley   +1 more source

Deconstructing lipid emulsion binding of amitriptyline: potential significance for phospholipid emulsifier

open access: yesToxicology Communications
Background Lipid emulsion (LE) consists of soybean or other oil emulsified with phospholipid. We explored relative binding effects of LE, phospholipid liposomes (PLL), and soy oil (Soy).Methods We added 4 micrograms of amitriptyline to seven different 10 
Grant Cave   +4 more
doaj   +1 more source

MXene‐Enhanced Electromembrane Systems for Advanced Water Applications: A Review

open access: yesAdvanced Energy and Sustainability Research, Volume 7, Issue 1, January 2026.
MXenes, synthesized via etching, intercalation, and delamination, exhibit hydrophilicity, conductivity, tunability, and strength, enabling roles as membranes, electrodes, and hybrids in electrical‐driven membrane technologies. These systems leverage adsorption, catalysis, separation, and self‐cleaning but face challenges in stability, scalability ...
Zainab Alansari   +2 more
wiley   +1 more source

Effects of antidepressants on parameters, melondiadehyde, and diphenyl-2-picryl-hydrazyl levels in mice spermatozoa

open access: yesInternational Journal of Reproductive BioMedicine, 2018
Background: Prescribing antidepressant drugs is becoming common. These drugs are known to affect sexual functions. Objective: The study is aimed to assess the effects of amitriptyline and venlafaxine on sperm parameters and evaluate Malondialdehyde (MDA)
Ladan Bandegi   +5 more
doaj  

Beyond Oral Pain: A Unique Case of Burning Mouth Syndrome With Coexisting Vulvodynia and Cognitive Impairment in a Postmenopausal Woman

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Burning mouth syndrome (BMS) is a chronic pain condition characterized by persistent intraoral burning without an identifiable cause, predominantly affecting postmenopausal women. We present a unique case of a 63‐year‐old Ethiopian woman exhibiting a distinctive triad of BMS, vulvodynia, and progressive cognitive decline, an association not ...
Rachel Annam   +2 more
wiley   +1 more source

Insights Into Patient‐Level Exposure to Actionable Pharmacogenomic Medications in Australia Using a New National Pharmacogenomic Guideline

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 89-100, January 2026.
This study assessed the use of 35 pharmacogenomic (PGx) medications listed in the Royal College of Pathologists of Australasia (RCPA) guideline, estimated the potential costs of subsidizing PGx testing in Australia, and predicted related prescribing changes.
Bella D. Ianni   +3 more
wiley   +1 more source

Rules of Thumb for Estimating Drug Levels in Breast Milk: How Well Do They Work?

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 101-108, January 2026.
The American Academy of Pediatrics and the World Health Organization recommend exclusive breastfeeding for the first 6 months of life due to extensive benefits for the maternal–infant dyad. While over 90% of mothers initiate breastfeeding, continuation drops to 35% by 6 months, often due to concerns about medication safety.
Juliya Gasparyan   +3 more
wiley   +1 more source

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