Results 91 to 100 of about 29,828 (259)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux   +26 more
wiley   +1 more source

Long-Term Pulmonal Therapy of Cystic Fibrosis-Patients with Amitriptyline

open access: yesCellular Physiology and Biochemistry, 2016
Background/Aims: Several recent clinical studies revealed an accumulation of ceramide in bronchial epithelial cells of patients with cystic fibrosis (CF).
Constantin Adams   +8 more
doaj   +1 more source

The effect of amitriptyline treatment on the growth hormone response to apomorphine.

open access: yes, 2016
The growth hormone response to subcutaneous administration of the dopamine agonist apomorphine (0.005 mg/kg) was assessed in six normal male subjects before and at the end of a course of amitriptyline.

core   +1 more source

Depressive and Anxiety Symptoms in Vestibular Migraine and Probable Vestibular Migraine

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Introduction It has been previously reported that patients with vestibular migraine (VM) are more prone to anxiety and depressive symptoms. However, the association between the pathophysiology of VM and anxiety and depressive symptoms is still unclear.
Chisato Fujimoto   +6 more
wiley   +1 more source

Amitriptyline

open access: yesReactions Weekly
Thour A, Alag P, Patel P, Marwaha R.
europepmc   +3 more sources

Amitriptyline influences the mechanical withdrawal threshold in bone cancer pain rats by regulating glutamate transporter GLAST

open access: yesMolecular Pain, 2019
Patients with cancer, especially breast, prostate, and lung cancer, commonly experience bone metastases that are difficult to manage and are associated with bone cancer pain. Amitriptyline is often used to treat chronic pain, such as neuropathic pain. In
Simeng Ma   +7 more
doaj   +1 more source

Antidepressant behavioral effects of duloxetine and amitriptyline in the rat forced swimming test Efeitos antidepressivos da duloxetina e da amitriptilina no teste do nado forçado em ratos

open access: yesActa Cirúrgica Brasileira, 2008
PURPOSE: To compare the effects of the antidepressant drugs duloxetine and amitriptyline on depressive behaviors in rats. METHODS: Fifteen male Wistar rats were given systemic injections of duloxetine, amitriptyline or saline prior to a Forced Swimming ...
Honório Sampaio Menezes   +7 more
doaj   +1 more source

Therapeutic plasma exchange in amitriptyline intoxication: Case report and review of the literature

open access: yes, 2011
Severe amitriptyline poisoning results in cardiac and neurological toxicity and continues to be a leading cause of significant morbidity and mortality both in children and adults.
Keskin, Ali   +15 more
core   +1 more source

Neuropathic pain in cerebral palsy and related genetic conditions: A scoping review of prevalence, characteristics, and management

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To map existing evidence on neuropathic pain in cerebral palsy (CP) and related genetic conditions, including prevalence, descriptors, assessment methods, and management. Method Following prospective registration, five databases (Ovid MEDLINE, Embase, CINAHL, Web of Science, Google Scholar) were searched in June 2025.
Aayushi Khillan   +8 more
wiley   +1 more source

Topical amitriptyline in healthy volunteers [PDF]

open access: yes, 2003
Background and Objectives: The antidepressant amitriptyline is used as an adjuvant in the treatment of a variety of chronic pain conditions. This drug interacts with many receptors and ion channels, such as Na ϩ channels. In a randomized, double-blinded,
B A   +5 more
core  

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