Results 101 to 110 of about 47,538 (286)

Correlates of Positive Response to Therapeutic Hydrodistension in Interstitial Cystitis/Bladder Pain Syndrome

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims The objective of this study was to assess the duration and clinical correlates of positive response in interstitial cystitis/bladder pain syndrome patients undergoing therapeutic bladder hydrodistension (HOD) or HOD with electrofulguration (for those with Hunner lesions).
Dylan T. Wolff, Carl D. Langefeld, Julie T. Call, Gopal Badlani, Robert J. Evans, Stephen J. Walker   +5 more
wiley   +1 more source

Long-Term Pulmonal Therapy of Cystic Fibrosis-Patients with Amitriptyline

Cellular Physiology and Biochemistry, 2016
Background/Aims: Several recent clinical studies revealed an accumulation of ceramide in bronchial epithelial cells of patients with cystic fibrosis (CF).
Constantin Adams, Vanya Icheva, Caroline Deppisch, Josefine Lauer, Gloria Herrmann, Ute Graepler-Mainka, Susanne Heyder, Erich Gulbins, Joachim Riethmueller   +8 more
doaj   +1 more source

Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update [PDF]

, 2017
CYP2D6 and CYP2C19 polymorphisms affect the exposure, efficacy and safety of tricyclic antidepressants (TCAs), with some drugs being affected by CYP2D6 only (e.g., nortriptyline and desipramine) and others by both polymorphic enzymes (e.g., amitriptyline,
Bishop, Jeffrey R., Caudle, Kelly E., Dunnenberger, Henry M., Ellingrod, Vicki L., Gaedigk, Andrea, Hicks, J. Kevin, Kharasch, Evan D., Klein, Teri E., Müller, Daniel J., Sangkuhl, Katrin, Shimoda, Kazutaka, Skaar, Todd C., Stingl, Julia C., Swen, Jesse J.   +13 more
core   +1 more source

‘I Wish I Fought for Myself More Instead of Just Letting Doctors Dismiss Me’: A Combined Qualitative Analysis of Four Cohorts of Aotearoa New Zealand Endometriosis Patients

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Endometriosis is a chronic condition that affects around 10% of New Zealand women and people presumed female at birth, however, limitations in diagnosis and management mean patients wait a decade on average from symptom onset to diagnosis.
Katherine Ellis, Rachael Wood
wiley   +1 more source

Antidepressant behavioral effects of duloxetine and amitriptyline in the rat forced swimming test Efeitos antidepressivos da duloxetina e da amitriptilina no teste do nado forçado em ratos

Acta Cirúrgica Brasileira, 2008
PURPOSE: To compare the effects of the antidepressant drugs duloxetine and amitriptyline on depressive behaviors in rats. METHODS: Fifteen male Wistar rats were given systemic injections of duloxetine, amitriptyline or saline prior to a Forced Swimming ...
Honório Sampaio Menezes, Bárbara Beatriz Moreira Bueno, Leandro Ciulla, Alexandre Schuh, Fernanda de Freitas Luz, Rafael José Vargas Alves, Milena Pacheco Abegg, Sílvia Letícia Merceo Bacchi Cirino   +7 more
doaj   +1 more source

Antidepressants in the Management of Chronic Pain Syndromes [PDF]

, 1990
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90213/1/j.1875-9114.1990.tb02582.x ...
Chaffee, Betty J., Egbunike, Ifeanyi G.
core   +1 more source

Organ Donation After Medical Aid in Dying: An Ethical Overview

Bioethics, EarlyView.
ABSTRACT Organ Donation after Medical Aid in Dying (OD‐MAiD) is currently practised in four countries: Belgium, Canada, the Netherlands, and Spain. While OD‐MAiD shares some similarities with MAiD (absent the possibility of organ donation) and with standard organ donation protocols, the combination of OD and MAiD involves unique circumstances that ...
David Rodríguez‐Arias, María Victoria Martínez‐López, Luis Espericueta, Gonzalo Díaz‐Cobacho, Jed Adam Gross, Janet Delgado   +5 more
wiley   +1 more source

Investigating the protective role of the natural hormone Melatonin, in reducing drug-induced cardiotoxicity in the therapy of chronic diseases [PDF]

, 2019
Heart failure (HF) is a highly complex disorder and a major end-point of cardiovascular diseases (CVD). The pathogenesis of HF is mostly unresolved but involves interplay between cardiac structural and electrical remodelling, metabolic alterations, cell ...
Kasi Ganeshan, T., Kasi Ganeshan, T.
core  

A single dose of hypnotic corrects sleep and EEG abnormalities in symptomatic Huntington's disease mice. [PDF]

, 2016
Sleep and electroencephalogram abnormalities are prominent early features of Huntington's disease (HD) that typically appear before the onset of characteristic motor symptoms.
Kantor, Sandor, Morton, A Jennifer, Varga, Janos   +2 more
core   +2 more sources

Urologic chronic pelvic pain syndrome 3‐year symptom trajectories: the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Symptom Patterns Study

BJU International, EarlyView.
Objectives To characterise 3‐year pelvic pain and urinary symptom trajectories and to identify baseline factors associated with urologic chronic pelvic pain syndrome (UCPPS) improvement. Patients and Methods The Trans‐Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Symptom Patterns Study was a multicentre, prospective cohort study
Catherine S. Bradley, Mengying You, Wensheng Guo, Niloofar Afari, Priyanka Gupta, Karl J. Kreder, John N. Krieger, H. Henry Lai, Susan K. Lutgendorf, Bruce D. Naliboff, Siobhan Sutcliffe, Frank Tu, David A. Williams, Tara McWilliams, Larissa Rodriguez, J. Richard Landis, for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network   +16 more
wiley   +1 more source