Results 101 to 110 of about 42,887 (227)

Antidepressant behavioral effects of duloxetine and amitriptyline in the rat forced swimming test Efeitos antidepressivos da duloxetina e da amitriptilina no teste do nado forçado em ratos

open access: yesActa Cirúrgica Brasileira, 2008
PURPOSE: To compare the effects of the antidepressant drugs duloxetine and amitriptyline on depressive behaviors in rats. METHODS: Fifteen male Wistar rats were given systemic injections of duloxetine, amitriptyline or saline prior to a Forced Swimming ...
Honório Sampaio Menezes   +7 more
doaj   +1 more source

New players in the preventive treatment of migraine. [PDF]

open access: yes, 2015
Migraine is a common, chronic disorder of the brain causing much disability, as well as personal, familial and societal impact. Several oral preventive agents are available in different countries for the prevention of migraine, but none have performed ...
Mitsikostas, Dimos D, Rapoport, Alan M
core   +3 more sources

Migraine and Restless Legs Syndrome: A Meta‐Analysis

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Restless legs syndrome is a sensorimotor disorder of sleep/wake regulation that frequently coexists with migraine, affecting patients' quality of life. This study aimed to estimate the prevalence of restless legs syndrome in individuals with migraine and to explore the associated clinical, demographic and behavioural aspects.
Florindo d'Onofrio   +8 more
wiley   +1 more source

Antidepressants in the Management of Chronic Pain Syndromes [PDF]

open access: yes, 1990
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90213/1/j.1875-9114.1990.tb02582.x ...
Chaffee, Betty J., Egbunike, Ifeanyi G.
core   +1 more source

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

open access: yesPhotochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio   +4 more
wiley   +1 more source

A Case of Aseptic Meningitis Presenting With Widespread Non-Dermatomal Neuropathic Pain. [PDF]

open access: yesJ Gen Fam Med
ABSTRACT Aseptic meningitis occasionally causes neuropathic pain in a dermatomal distribution, but widespread non‐dermatomal pain is extremely rare. We report a case of a 62‐year‐old man with ulcerative colitis who developed neuropathic pain involving the head, trunk, and limbs.
Komoda J.
europepmc   +2 more sources

Investigating the protective role of the natural hormone Melatonin, in reducing drug-induced cardiotoxicity in the therapy of chronic diseases [PDF]

open access: yes, 2019
Heart failure (HF) is a highly complex disorder and a major end-point of cardiovascular diseases (CVD). The pathogenesis of HF is mostly unresolved but involves interplay between cardiac structural and electrical remodelling, metabolic alterations, cell ...
Kasi Ganeshan, T., Kasi Ganeshan, T.
core  

Possible involvement of keratinocyte‐derived microvesicle particles in human photosensitivity disorders

open access: yesPhotochemistry and Photobiology, EarlyView.
In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju   +13 more
wiley   +1 more source

Impacts of compound properties and sediment characteristics on the sorption behaviour of pharmaceuticals in aquatic systems [PDF]

open access: yes, 2016
Sorption is a key factor in determining the persistence, attenuation and bioavailability of sediment-associated contaminants. However, our understanding of the sorption behaviour of pharmaceuticals in sediments is poor. In this study, we investigated the
Al-Khazrajy, Omar S A   +1 more
core   +1 more source

Orthodontic treatment in periodontitis patients

open access: yesPeriodontology 2000, EarlyView.
Abstract This paper examines the complex interplay between orthodontic intervention and periodontal conditions in individuals with periodontitis. It outlines diagnostic and treatment approaches for adolescents and adults, considering their distinct periodontal, dental, and behavioral needs.
Tali Chackartchi   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy