Results 111 to 120 of about 47,538 (286)

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Cognitive function and lifetime features of depression and bipolar disorder in a large population sample: Cross-sectional study of 143,828 UK Biobank participants [PDF]

, 1996
Background: This study investigated differences in cognitive performance between middle-aged adults with and without a lifetime history of mood disorder features, adjusting for a range of potential confounders.
Cullen, B., Deary, I..J., Evans, J.J., Gallacher, J., Mackay, D.F., Martin, D., McIntosh, A., Nicholl, B.I., Pell, J.P., Smith, D.J., Ul-Haq, Z.   +10 more
core   +2 more sources

Opsoclonus‐Myoclonus: Not Always Paraneoplastic

Movement Disorders Clinical Practice, EarlyView.
Fernanda Lustosa Cabral Gomez, Luiz José Malta Gaia Ferreira Júnior, Sofia Mônaco Gama, Fabiano Moulin de Moraes, Flávio Moura Rezende Filho   +4 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Sleep quality and its correlates in people with epilepsy: A multicenter cross‐sectional study in Germany

Epilepsia, EarlyView.
Abstract Objective Sleep disturbances and epilepsy are closely interrelated. This study aimed to examine associations between sleep quality, affective symptoms, and quality of life (QoL) in people with epilepsy (PWE), and to identify clinical and sociodemographic factors linked to impaired sleep. Methods We conducted a multicenter cross‐sectional study
Johann Philipp Zöllner, Catrin Mann, Laurent Willems, Felix von Podewils, Lisa Langenbruch, Laura Bierhansl, Susanne Knake, Katja Menzler, Juliane Schulz, Bernadette Gaida, Felix Rosenow, Adam Strzelczyk   +11 more
wiley   +1 more source

Persistent postural‐perceptual dizziness versus vestibular migraine: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This article reviews the differences and similarities between persistent postural‐perceptual dizziness (PPPD) and vestibular migraine. Background PPPD is considered a chronic functional vestibular disorder characterized by persistent dizziness, unsteadiness, nonspinning vertigo, and often exacerbated by upright posture, movement, or ...
David Moreno‐Ajona
wiley   +1 more source

Effects of Desipramine, Amitriptyline, and Fluoxetine on Pain in Diabetic Neuropathy [PDF]

, 1992
Mitchell B. Max, Sue Lynch, Joanne Muir, Susan E. Shoaf, Bruce M Smoller, Ronald Dubner   +5 more
openalex   +1 more source

Some t-tests for N-of-1 trials with serial correlation

, 2019
N-of-1 trials allow inference between two treatments given to a single individual. Most often, clinical investigators analyze an individual's N-of-1 trial data with usual t-tests or simple nonparametric methods.
Landes, Reid D., Tang, Jillian
core   +1 more source

Do patients with migraine and obesity receive different treatments? Insights from real‐world data

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Patients with obesity often experience stigma in healthcare, which may lead to underdiagnosis or undertreatment. In the context of pain management, and migraine specifically, patients with obesity are more likely to receive both opioid and non‐opioid analgesics.
Keshet Pardo, Maor Mermelstein, Gal Tsur, Shlomit Yust‐Katz   +3 more
wiley   +1 more source

Antidepressant amitriptyline‐induced matrix metalloproteinase‐9 activation is mediated by Src family tyrosine kinase, which leads to glial cell line‐derived neurotrophic factor mRNA expression in rat astroglial cells

Neuropsychopharmacology Reports, 2019
Background Astrocytes have been implicated in the pathophysiology of mood disorders and in the mechanism of the pharmacological effects of antidepressant drugs by the production of neurotrophic/growth factors.
Hiromi Abe, Naoto Kajitani, Mami Okada‐Tsuchioka, Wataru Omori, Masahide Yatsumoto, Minoru Takebayashi   +5 more
doaj   +1 more source