Results 151 to 160 of about 47,538 (286)

Hyperfiltration and Metabolism Before and After a Low‐Calorie, Pre‐Gastric Bypass Surgery Diet: Significance for Concentrations of Hydrophilic and Lipophilic Drugs

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 1, January 2026.
ABSTRACT Psychotropic drug concentrations increase/decrease with hydrophilicity/lipophilicity after a low‐calorie pre‐bariatric surgery diet. To investigate underlying mechanisms, body weight and serum creatinine/cystatin C changes over the diet period were characterized and suggested to reflect changes in glomerular filtration and metabolic capacity ...
Magnus A. B. Axelsson   +1 more
wiley   +1 more source

Reducing Anticholinergic Burden in Hospitalised Older Adults: Analysis From the INFAR Study

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 1, January 2026.
ABSTRACT This study aimed to evaluate the effectiveness of pharmacist‐led medication reviews in reducing the anticholinergic burden of hospitalised patients with cardiovascular diseases (CVDs), to identify which anticholinergic medications were most frequently prescribed or discontinued during hospitalisation and to investigate factors associated with ...
Romana Santos Gama   +4 more
wiley   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, Volume 36, Issue 1, January 2026.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

Amitriptyline modifies the visceral hypersensitivity response to acute stress in the irritable bowel syndrome [PDF]

open access: bronze, 2008
Nora Thoua   +6 more
openalex   +1 more source

Consider melatonin for migraine prevention [PDF]

open access: yes, 2017
An effective migraine prevention alternative with minimal adverse effects Melatonin is an accessible and affordable option for preventing migraine headaches in chronic ...
Langner, Shannon   +2 more
core  

Exploring Nasal Structural‐Microbial Interactions in Multiple Sclerosis‐Associated Olfactory Impairment

open access: yesAnnals of Clinical and Translational Neurology, Volume 12, Issue 12, Page 2546-2557, December 2025.
ABSTRACT Background Olfactory dysfunction is frequently observed in patients with multiple sclerosis (MS); however, its underlying mechanisms remain poorly understood. To date, no studies have directly examined the nasal mucosal microbiota in MS. This study aimed to explore potential relationships among olfactory function, nasal microbiota composition,
Zidan Gao   +5 more
wiley   +1 more source

Amitriptyline increases survival rate and neurite outgrowth of spiral ganglion Neurons

open access: hybrid, 2018
Jennis Gabrielpillai   +3 more
openalex   +1 more source

Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022: A repeated cross‐sectional study

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 12, Page 3432-3444, December 2025.
Aims Analgesic medicines are an important component of pain management, with different medicines carrying different risks and benefits. The aim of this study was to examine trends in analgesic prescribing in Ireland and England between 2014 and 2022. Methods Monthly data on medicines prescribed and dispensed in primary care were used. For Ireland, data
Molly Mattsson   +8 more
wiley   +1 more source

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