Results 131 to 140 of about 70,737 (298)

Effect of Amlodipine on The Concentration of Carotid Tissue Endothelin in High Cholesterol Fed Rabbits

open access: yesپزشکی بالینی ابن سینا, 2008
Introduction & Objective: Endothelin-1 is involved in induction and progression of atherosclerosis. Since several changes with abnormality in transferring of calcium ions have been seen in atherosclerotic vessels, it is supposed that calcium channel ...
Mostafa Mohammadi   +2 more
doaj  

The Immune Microenvironment in Liver Cancer: From Analysis to Targeting

open access: yesAdvanced Science, Volume 12, Issue 47, December 18, 2025.
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan   +5 more
wiley   +1 more source

K022: Effect of combination therapy (ANG II antagonist, valsartan and a calcium channel blocker) in a hypertensive model of diabetic nephropathy [PDF]

open access: yes, 2017
Recently, it has been suggested that in the context of diabetes and hypertension, more aggressive blood pressure targets should be considered. To achieve these levels of blood pressure control, it is likely that combination therapy will need to be used ...
Allen, T.J.   +3 more
core  

Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers. [PDF]

open access: yes, 2018
Background Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to evaluate the association between different classes of antihypertensive agents with nonrenal outcomes, especially in advanced ...
Johansen, Kirsten L   +4 more
core  

VEXAS Syndrome Presenting With Pleuritis

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
Chest CT showing pleural effusion and pleural thickening in a patient with recurrent pleuritis (A), and bone marrow smear demonstrating vacuolated myeloid precursors characteristic of VEXAS syndrome (B). ABSTRACT Elderly men with pleuritis, systemic inflammation, cytopenias, and bone‐marrow vacuolization may have VEXAS due to somatic UBA1 mutations ...
Makoto Ito   +4 more
wiley   +1 more source

Myasthenia Gravis in a Child With Schimke Immuno‐Osseous Dysplasia: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT We report a rare association between Schimke immune‐osseous dysplasia and myasthenia gravis. Clinicians should be aware of potential autoimmune neuromuscular complications in SIOD, as early recognition and tailored immunosuppression may improve prognosis.
Mohamed S. Al Riyami   +7 more
wiley   +1 more source

Comparisons of the pharmacokinetics and tolerability of fixed-dose combinations of amlodipine besylate/losartan and amlodipine camsylate/losartan in healthy subjects: a randomized, open-label, single-dose, two-period, two-sequence crossover study

open access: yesDrug Design, Development and Therapy, 2016
YoonJung Choi,1 SeungHwan Lee,2 Sang-Min Cho,3 Won-Ho Kang,3 Kyu-Yeol Nam,4 In-Jin Jang,1 Kyung-Sang Yu1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine, 2Clinical Trials Center, Seoul National ...
Choi Y   +6 more
doaj  

Amlodipine in patients with arterial hypertension and hypertensive nephropathy [PDF]

open access: yes, 2012
Scientific supervisor: Y.O. AtamanIt is well known that prolonged increasing of blood pressure accompanied by the affection of many internal organs, particularly kidneys.
Pryvalova, A.O.
core  

A Case of Recurrent Painful Ophthalmoplegia Following COVID‐19: Evolution From Optic Neuritis to Tolosa–Hunt Syndrome

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Tolosa–Hunt syndrome could be considered in patients with painful ophthalmoplegia following COVID‐19 infection, but caution should be exercised in attributing causality. Careful exclusion of alternative diagnoses is essential. Corticosteroids usually produce quick clinical relief.
Sanjiv Poudel   +5 more
wiley   +1 more source

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