Introduction & Objective: Endothelin-1 is involved in induction and progression of atherosclerosis. Since several changes with abnormality in transferring of calcium ions have been seen in atherosclerotic vessels, it is supposed that calcium channel ...
Mostafa Mohammadi +2 more
doaj
The Immune Microenvironment in Liver Cancer: From Analysis to Targeting
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan +5 more
wiley +1 more source
K022: Effect of combination therapy (ANG II antagonist, valsartan and a calcium channel blocker) in a hypertensive model of diabetic nephropathy [PDF]
Recently, it has been suggested that in the context of diabetes and hypertension, more aggressive blood pressure targets should be considered. To achieve these levels of blood pressure control, it is likely that combination therapy will need to be used ...
Allen, T.J. +3 more
core
Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers. [PDF]
Background Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to evaluate the association between different classes of antihypertensive agents with nonrenal outcomes, especially in advanced ...
Johansen, Kirsten L +4 more
core
Simultaneous Estimation of Aliskiren and Amlodipine in Combined Tablet Formulation by Simultaneous Equation and First Derivative Spectroscopic Methods [PDF]
Neelam Yadav
openalex +1 more source
VEXAS Syndrome Presenting With Pleuritis
Chest CT showing pleural effusion and pleural thickening in a patient with recurrent pleuritis (A), and bone marrow smear demonstrating vacuolated myeloid precursors characteristic of VEXAS syndrome (B). ABSTRACT Elderly men with pleuritis, systemic inflammation, cytopenias, and bone‐marrow vacuolization may have VEXAS due to somatic UBA1 mutations ...
Makoto Ito +4 more
wiley +1 more source
Myasthenia Gravis in a Child With Schimke Immuno‐Osseous Dysplasia: A Case Report
ABSTRACT We report a rare association between Schimke immune‐osseous dysplasia and myasthenia gravis. Clinicians should be aware of potential autoimmune neuromuscular complications in SIOD, as early recognition and tailored immunosuppression may improve prognosis.
Mohamed S. Al Riyami +7 more
wiley +1 more source
YoonJung Choi,1 SeungHwan Lee,2 Sang-Min Cho,3 Won-Ho Kang,3 Kyu-Yeol Nam,4 In-Jin Jang,1 Kyung-Sang Yu1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine, 2Clinical Trials Center, Seoul National ...
Choi Y +6 more
doaj
Amlodipine in patients with arterial hypertension and hypertensive nephropathy [PDF]
Scientific supervisor: Y.O. AtamanIt is well known that prolonged increasing of blood pressure accompanied by the affection of many internal organs, particularly kidneys.
Pryvalova, A.O.
core
ABSTRACT Tolosa–Hunt syndrome could be considered in patients with painful ophthalmoplegia following COVID‐19 infection, but caution should be exercised in attributing causality. Careful exclusion of alternative diagnoses is essential. Corticosteroids usually produce quick clinical relief.
Sanjiv Poudel +5 more
wiley +1 more source

