Results 31 to 40 of about 70,737 (298)

Olmesartan-based monotherapy vs combination therapy in hypertension: A meta-analysis based on age and chronic kidney disease status. [PDF]

, 2017
Antihypertensive monotherapy is often insufficient to control blood pressure (BP). Several recent guidelines advocate for initial combination drug therapy in many patients. This meta-analysis of seven randomized, double-blind studies (N = 5888) evaluated
Bakris, George, Deedwania, Prakash, Reimitz, Paul-Egbert, Weber, Michael   +3 more
core   +1 more source

Nifedipine and Amlodipine Are Associated With Improved Mortality and Decreased Risk for Intubation and Mechanical Ventilation in Elderly Patients Hospitalized for COVID-19

Cureus, 2020
Dihydropyridine calcium channel blockers (CCB) are typically used agents in the clinical management of hypertension. Yet, they have also been utilized in the treatment of various pulmonary disorders with vasoconstriction.
I. Solaimanzadeh
semanticscholar   +1 more source

The Method of Forecasting of the Indicators for Drug Reimbursement to Patients with Cardiovascular Diseases in Ukraine [PDF]

, 2019
The aim of the study is to develop a method for forecasting the indicators for drug reimbursement to patients with cardiovascular diseases (CVD) in Ukraine within the framework of the government program “Available medicines”.Materials and methods ...
Kurylenko, Y. (Yuliia), Nazarkina, V. (Viktoriya), Nemchenko, A. (Alla)   +2 more
core   +3 more sources

Improvement of In Vitro Dissolution of the Poor Water-Soluble Amlodipine Drug by Solid Dispersion with Irradiated Polyvinylpyrrolidone

ACS Omega, 2020
The aim of this study was to increase both the rates of dissolution and bioavailability of the amlodipine (Amlo) drug. Due to the low cost, high solubility, and amorphous state, polyvinylpyrrolidone (PVP) has been used as a drug carrier in the solid ...
M. Ghobashy, D. Alshangiti, S. Alkhursani, S. A. Al-Gahtany, F. Shokr, M. Madani   +5 more
semanticscholar   +1 more source

Bioequivalence study of fixed-dose combination Losartan + amlodipine + rosuvastatin Sanofi in comparison with coadministered fixed- dose combination Lozap® AM and monocomponent drug Crestor® in healthy subjects

Фармакокинетика и Фармакодинамика, 2022
Introduction. The advantages of fixed-dose combination losartan + amlodipine + rosuvastatin compared to mono-drugs and two-component combinations are to increase the therapeutic efficacy, to reduce the cost of the product and to make the drug easier to ...
A. L. Khokhlov, D. Yu. Grebenkin, E. K. Faeva, V. I. Kazey, A. A. Khokhlov, A. E. Miroshnikov, O. V. Lebedeva   +6 more
doaj   +1 more source

Systemic hypertension in cats with acute kidney injury [PDF]

, 2017
Retrospective study of cats presenting to the Queen Mother Hospital for Animals, Royal Veterinary College with acute kidney injury between 2007 and 2015.
Acierno, Basile, Behrend, Belew, Bijsmans, Braun, Brown, Campese, Chertow, Chetboul, Geigy, Harison, Hoste, Hoste, Jacob, Jepson, Jepson, Klag, Kletzmayr, Lee, Maggio, Monaghan, Pouchelon, Ravera, Segev, Stiles, Syme, Uchino, Wehner   +28 more
core   +1 more source

COMPARATIVE STUDY OF EFFICIENCY AND SAFETY OF THE NEW DRUG OF AMLODOPINE – S-AMLODOPINE IN PATIENTS WITH ARTERIAL HYPERTENSION OF I-II DEGREE

Рациональная фармакотерапия в кардиологии, 2016
Aim. To evaluate efficacy and safety of a new drug of amlodipine – S-amlodipine (Azomex, Emcur, India) compared to original drug of racemic amlodipine (Norvasc, Pfizer, USA) in patients with arterial hypertension (HT) of I-II grade.Material and methods ...
M. A. Maksimova, Y. V. Lukina, S. N. Tolpygina, E. V. Shilova, N. A. Dmitrieva, S. Y. Martsevich   +5 more
doaj   +1 more source

Development and Validation of an HPLC Method Using an Experimental Design for Analysis of Amlodipine Besylate and Enalapril Maleate in a Fixed-dose Combination

Turkish Journal of Pharmaceutical Sciences, 2020
Objectives The aim of this study was to develop and optimize a simple, cost-effective, and robust high-performance liquid chromatography (HPLC) method by taking an experimental design approach to the assay and dissolution analysis of amlodipine besylate ...
Diren Sarısaltık Yaşın, Alev Arslantürk Bingül, Alptuğ Karaküçük, Z. Teksin   +3 more
semanticscholar   +1 more source

18F‐Radiopharmaceutical Diversification Enabled by Deaminative Cross‐Electrophile Couplings

Angewandte Chemie, EarlyView.
A general Ni‐mediated (C)sp2–(C)sp3 cross‐coupling expedites access to 18F‐radiopharmaceuticals, essential for positron emission tomography imaging and drug discovery. This late‐stage diversification approach was implemented across three user‐friendly automated protocols affording 18F‐radiotracers in sufficient quantities for imaging.
Isabella F. Ogilvy, Joseph Ford, Sebastiano Ortalli, Evelien Renders, Thomas R. Hayes, Shuanglong Liu, Inne Mortiers, Anastasia Nikolopoulou, Alexandre M. Sorlin, Andrés A. Trabanco, Matthew Tredwell, Peter J. J. A. Buijnsters, Rhys Salter, Véronique Gouverneur   +13 more
wiley   +2 more sources

Synergism of amlodipine and telmisartan or candesartan on blood pressure reduction by using SynergyFinder 3.0 and probability sum test in vivo

Pharmacology Research & Perspectives, 2023
This study was designed to evaluate the synergism of two couples of antihypertensive drugs (amlodipine + telmisartan and amlodipine + candesartan) on blood pressure reduction in vivo by both SynergyFinder 3.0 and probability sum test.
Tian Xia, Lu‐Lu Xu, Peng‐Yue Guo, Wan‐Ting Shi, Yan‐Qiong Cheng, Ai‐Jun Liu   +5 more
doaj   +1 more source