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Sodium Amytal – No Longer Prescribed, but Still Relevant (And Dangerous!) [PDF]

open access: yesBJPsych Open
Aims: Sodium amytal is a barbiturate medication, first synthesised in Germany in the 1920s to treat anxiety and sleep disorders; as well as being used as an anaesthetic.
Conor Brown
doaj   +2 more sources

Preoperative embolization of feeding arteries in glioblastoma: Technical strategies and clinical utility [PDF]

open access: yesActa Neurochirurgica
Background Maximal safe resection—balancing aggressive tumor removal with neurological preservation—is essential in glioblastoma surgery. Cerebral angiography enables identification of the dominant hemisphere, feeding arteries, and vessels crossing ...
Masashi Uchida   +11 more
doaj   +2 more sources

Discordant Wada and fMRI language lateralization: a case report [PDF]

open access: yesJournal of International Medical Research
Functional MRI (fMRI) is gaining importance in the preoperative assessment of language for presurgical planning. However, inconsistencies with the Wada test might arise.
Yu Peng, Jiwen Xu, Zhaoxin Wang
doaj   +2 more sources

Concordance between Wada, Transcranial Magnetic Stimulation, and Magnetoencephalography for Determining Hemispheric Dominance for Language: A Retrospective Study [PDF]

open access: yesBrain Sciences
Determination of language hemispheric dominance (HD) in patients undergoing evaluation for epilepsy surgery has traditionally relied on the sodium amobarbital (Wada) test.
Negar Noorizadeh   +8 more
doaj   +2 more sources

Bilateral Wada test: Amobarbital or propofol? [PDF]

open access: yesSeizure: the Journal of the British Epilepsy Association, 2014
The Wada test is still the gold standard procedure to predict language and memory deficits before temporal lobe epilepsy surgery. As amobarbital was no longer available, our aim was to validate propofol as an alternative.We retrospectively studied 47 patients who underwent a bilateral intracarotid procedure, performed with amobarbital (18), or propofol
Gladys Barragan-Jason, L Valton
exaly   +4 more sources

Repeated Intracarotid Amobarbital Tests

open access: yesEpilepsia, 2007
Summary:  Rationale: Our goal was to determine the frequency of repeated intracarotid amobarbital test (IAT) at our center and to estimate the retest reliability of the IAT for both language and memory lateralization. Methods: A total of 1,249 consecutive IATs on 1,190 patients were retrospectively reviewed for repeat tests. Results: In 4% of patients
Tobias Loddenkemper   +2 more
exaly   +5 more sources

A STUDY OF THE INCLUSION COMPLEX OF AMOBARBITAL WITH HEPTAKIS (2,6-DI-O-METHYL)--CYCLODEXTRIN [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1991
The inclusion complex of amobarbital, a hypnotic and sedative agent, with heptakis (2,6-di-o-methyl)-b-cyclodextrin (DMCD) in aqueous solution and in the solid phase was studied by the solubility method, UV spectroscopy, infrared spectroscopy (IR ...
H. Mohamed, M. Abd El-Mohsen
doaj   +1 more source

Reversible blockade of complex I or inhibition of PKCβ reduces activation and mitochondria translocation of p66Shc to preserve cardiac function after ischemia. [PDF]

open access: yesPLoS ONE, 2014
Excess mitochondrial reactive oxygen species (mROS) play a vital role in cardiac ischemia reperfusion (IR) injury. P66Shc, a splice variant of the ShcA adaptor protein family, enhances mROS production by oxidizing reduced cytochrome c to yield H2O2 ...
Meiying Yang   +4 more
doaj   +1 more source

Evaluation of the density spectral array in the Wada test: report of six cases

open access: yesBrazilian Journal of Anesthesiology, 2021
Wada test is an invasive procedure used in the preoperative evaluation for epilepsy surgery to determine language lateralization, postoperative risk of amnesia syndrome, and to assess the risk of memory deficits. It involves injection of amobarbital into
Susana Pacreu   +4 more
doaj   +1 more source

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