Results 11 to 20 of about 2,396 (188)

Amobarbital effects on the posterior hippocampus during the intracarotid amobarbital test

Neurology, 1999
To relate functional effects on the hippocampus during the intracarotid amobarbital test (IAT) to its direct perfusion with amobarbital.In 17 patients with intractable temporal lobe epilepsy, 28 hemispheres were perfused with 2.3 mL of 10% solution of 200 mg amobarbital and 37 MBq 99mTc-hexamethylpropylene amine oxime (HMPAO).
H, Urbach, M, Kurthen, E, Klemm, T, Grunwald, D, Van Roost, D B, Linke, H J, Biersack, J, Schramm, C E, Elger   +8 more
openaire   +3 more sources

Discordant Wada and fMRI language lateralization: a case report [PDF]

Journal of International Medical Research
Functional MRI (fMRI) is gaining importance in the preoperative assessment of language for presurgical planning. However, inconsistencies with the Wada test might arise.
Yu Peng, Jiwen Xu, Zhaoxin Wang
doaj   +2 more sources

A critical review of high-frequency activity for functional mapping in SEEG. [PDF]

Epilepsia
Abstract Mapping functional brain networks is a critical component of stereo–electroencephalography (SEEG) evaluations. Although direct cortical stimulation (DCS) is the clinical gold standard, it has important limitations—particularly in mapping distributed, complex functions such as language and memory, where deficits may still occur despite ...
Sagar P, Hudson M, Rayner G, O'Brien TJ, Laing J, Neal A.   +5 more
europepmc   +2 more sources

Individual-specific resting-state networks predict language dominance in drug-resistant epilepsy. [PDF]

Epilepsia
Abstract Objective This study was undertaken to reliably estimate individual‐specific resting‐state cortical networks and determine whether language network topography can predict task‐based language dominance in drug‐resistant epilepsy. Methods We utilized a multisession hierarchical Bayesian model (MS‐HBM) trained on drug‐resistant epilepsy patients ...
Lim MJR, Zhang S, Pande S, Xue A, Kong R, Zaghloul K, Inati S, Yeo BTT.   +7 more
europepmc   +2 more sources

Alternatives to Sodium Amobarbital in the Wada Test

Annals of Pharmacotherapy, 2011
Objective: To review the literature and identify alternatives to sodium amobarbital for use in the Wada test. Data Sources: A search of PubMed (1960-October 2010) was performed using the following key words alone or in combination: Wada test ...
Cindy Wordell, Akta Patel, Dorata Szarlej   +2 more
exaly   +2 more sources

Characteristics and long-term outcomes of children with confirmed focal cortical dysplasia type 1 after epilepsy surgery: A population-based study. [PDF]

Epilepsia Open
Abstract Objective Focal cortical dysplasia type 1 (FCD1) is a rare and heterogeneous cause of drug‐resistant epilepsy (DRE) in children. Its clinical characteristics remain poorly understood, and surgical outcomes may be less favorable than in FCD2. We conducted a population‐based study to characterize the clinical presentation and long‐term seizure ...
Zheng V, Koroknay-Pál P, Lehtinen H, Gaily E, Karppinen A, Paetau A, Tynninen O, Leinonen H, Laakso A, Metsähonkala EL.   +9 more
europepmc   +2 more sources

Selective Amobarbital Test for the Determination of Language Function in Patients with Epilepsy with Frontal and Posterior Temporal Brain Lesions

Epilepsia, 1998
PURPOSE Selective amobarbital tests with selective temporary inactivation of the left frontal operculum and/or the left parietotemporal cortex were performed in 5 patients with left-hemispheric epileptogenic lesions in or adjacent to classical Broca's ...
Wieser HG, Valavanis A, Buck A, Yonekawa Y, Schiess R, Hajek M   +5 more
exaly   +2 more sources

National Prescribing Trends and Cost Analysis of Antidepressants, Anxiolytics, and Hypnotics in England, 2010-2023. [PDF]

Hum Psychopharmacol
ABSTRACT Introduction We describe prescribing of anxiolytics/hypnotics/antidepressants at an all‐England level between 2010 and 2023, taking account of the influence of the COVID‐19 pandemic‐period. Methods All Primary Care Prescribing data for England for anxiolytics/hypnotics/antidepressant agents taken as tablets or capsules from 1 January 2010 to ...
Stedman M, Davies M, Levy JW, Ingram J, Taylor D, Heald A.   +5 more
europepmc   +2 more sources

Concordance between Wada, Transcranial Magnetic Stimulation, and Magnetoencephalography for Determining Hemispheric Dominance for Language: A Retrospective Study [PDF]

Brain Sciences
Determination of language hemispheric dominance (HD) in patients undergoing evaluation for epilepsy surgery has traditionally relied on the sodium amobarbital (Wada) test.
Negar Noorizadeh, Roozbeh Rezaie, Jackie A. Varner, James W. Wheless, Stephen P. Fulton, Basanagoud D. Mudigoudar, Leigh Nevill, Christen M. Holder, Shalini Narayana   +8 more
doaj   +2 more sources

The intracarotid amobarbital or Wada test: unilateral or bilateral?

Acta Neurologica Scandinavica, 2009
In the Netherlands, presurgical screening for temporal lobe epilepsy (TLE) includes the intracarotid amobarbital procedure (IAP), consisting of two consecutive injections of amobarbital, ipsilateral and contralateral to the epileptic focus. We studied whether a bilateral IAP has added value to a unilateral, ipsilateral IAP.This population-based study ...
Uijl, S G, Leijten, F S S, Arends, J B A M, Parra, J, van Huffelen, A C, van Rijen, P C, Moons, K G M   +6 more
openaire   +3 more sources